Check out our most popular compounded medications! Get Started
Dashboard
Formulas

Diphenhydramine HCl 1.25 mg/mL/Hydrocortisone 0.5 mg/mL/Nystatin 20000 Units/mL/Tetracycline 12.5 mg/mL Oral Suspension

FDA-approved generic
Dose form
Suspension
Active ingredients
Diphenhydramine Hydrochloride
Hydrocortisone
Nystatin
Tetracycline Hydrochloride

This oral suspension is a liquid dosage form in which Diphenhydramine HCl, Hydrocortisone, Nystatin, and Tetracycline are uniformly dispersed throughout a liquid medium, ensuring a homogeneous mixture for administration. It is specifically formulated to treat inflammatory and allergic conditions, fungal infections, and bacterial infections in the oral cavity.

View more
For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Get started as a patient
Get Started
This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
Check if we ship to your state
No prescription yet?

Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Diphenhydramine Hydrochloride
Hydrocortisone
Nystatin
Tetracycline Hydrochloride
Suspension
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

Check your state

Available in

Tap a state to check it.

Our current service area

Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

Select a state on the map or use the checker.

Formula Information

A small arrow pointing down

This compounded oral suspension combines Diphenhydramine HCl 1.25 mg/mL, Hydrocortisone 0.5 mg/mL, Nystatin 20,000 Units/mL, and Tetracycline 12.5 mg/mL in a homogeneous liquid dosage form designed for oral administration. The suspension ensures that each active ingredient is uniformly dispersed throughout the liquid medium.

Diphenhydramine HCl acts as an antihistamine, providing relief from discomfort caused by allergic reactions in the oral cavity. It helps reduce symptoms such as itching, swelling, and pain. Hydrocortisone, a corticosteroid, works by reducing inflammation and suppressing immune responses, which can alleviate inflammation and irritation in the mouth.

Tetracycline, a broad-spectrum antibiotic, inhibits bacterial protein synthesis, helping to combat a variety of bacterial infections that may be present in the oral mucosa.

The combination of these ingredients addresses multiple potential causes of oral discomfort and lesions, including bacterial infections, fungal infections, inflammatory responses, and allergic reactions. This makes the formulation particularly useful for patients experiencing complex oral conditions where multiple therapeutic actions are beneficial.

Patients are advised to use this oral suspension as directed by their healthcare provider. The liquid form allows for easy administration and ensures direct contact of the medication with the affected areas in the mouth, enhancing the therapeutic effects. It's important to shake the bottle well before each use to ensure the proper distribution of the active ingredients.

Prescribers may consider this formulation for patients requiring a comprehensive treatment approach to oral mucosal conditions. The suspension can be tailored to meet specific patient needs, and dosing can be adjusted based on the severity of symptoms and response to therapy.

If you have any questions, reach out to us.

Drug Interactions

A small arrow pointing down

This compounded oral suspension contains Diphenhydramine HCl, Hydrocortisone, Nystatin, and Tetracycline, each of which can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions. It is crucial for both patients and prescribers to be aware of these interactions to ensure safe and appropriate use of this formulation.

Diphenhydramine HCl, an antihistamine, can cause sedation and may enhance the sedative effects of other central nervous system depressants, such as alcohol, benzodiazepines, opioids, and certain antidepressants. Patients should be advised to avoid or limit the use of these substances while taking this medication. Additionally, diphenhydramine may interact with monoamine oxidase inhibitors (MAOIs), potentially leading to increased anticholinergic effects, such as dry mouth, constipation, and urinary retention.

Hydrocortisone, a corticosteroid, can interact with a variety of medications. It may increase blood glucose levels, potentially reducing the efficacy of antidiabetic drugs. Patients with diabetes should monitor their blood sugar levels closely. Concurrent use with nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of gastrointestinal bleeding. Hydrocortisone can also affect the metabolism of certain drugs, such as warfarin, leading to altered anticoagulant effects. Regular monitoring of INR levels is recommended for patients on warfarin therapy.

Nystatin, an antifungal agent, is generally well-tolerated and has minimal systemic absorption when used orally. However, it is important to note that nystatin may interact with other antifungal medications, potentially leading to reduced efficacy. Patients should inform their healthcare provider of all antifungal treatments they are currently using to avoid potential interactions.

Tetracycline, an antibiotic, can interact with various medications and supplements. It may bind to calcium, magnesium, aluminum, and iron, reducing its absorption and effectiveness. Patients should avoid taking tetracycline with dairy products, antacids, or iron supplements. Additionally, tetracycline can decrease the effectiveness of oral contraceptives, so alternative or additional contraceptive measures should be considered. It may also interact with anticoagulants, potentially enhancing their effects and increasing the risk of bleeding.

Patients and prescribers should be vigilant about potential drug interactions when using this compounded oral suspension. A comprehensive review of the patient's current medication regimen, including over-the-counter drugs and supplements, is essential to minimize the risk of adverse interactions. If you have any questions or concerns about drug interactions with this formulation, please reach out to us for further assistance.

How Does it Work

A small arrow pointing down

This compounded oral suspension is a carefully formulated medication designed to deliver a combination of active ingredients, each serving a specific therapeutic purpose. The liquid dosage form ensures that the ingredients are uniformly dispersed throughout the medium, providing a homogeneous mixture that facilitates accurate dosing and ease of administration. This formulation is particularly beneficial for patients who may have difficulty swallowing tablets or capsules, such as children or the elderly, and allows for flexible dosing adjustments as needed.

Diphenhydramine HCl, an antihistamine, works by blocking the action of histamine, a substance in the body that causes allergic symptoms. By inhibiting histamine receptors, diphenhydramine helps alleviate symptoms such as itching, swelling, and rashes. Its sedative properties can also provide relief from discomfort and promote rest, which is beneficial in managing symptoms that may disrupt sleep.

Hydrocortisone, a corticosteroid, functions by reducing inflammation and suppressing the immune response. By modulating the body's immune response, hydrocortisone aids in the management of conditions that involve excessive inflammation, providing relief from discomfort and promoting healing.

Nystatin is an antifungal agent that targets fungal infections, particularly those caused by Candida species. It works by binding to the sterols in the fungal cell membrane, creating pores that lead to the leakage of essential cellular components, ultimately causing cell death.

Tetracycline, a broad-spectrum antibiotic, inhibits bacterial protein synthesis by binding to the 30S ribosomal subunit, preventing the addition of amino acids to the growing peptide chain. This action effectively halts bacterial growth and replication, making tetracycline useful in treating a variety of bacterial infections. Its inclusion in this formulation helps address bacterial components of mixed infections, ensuring comprehensive antimicrobial coverage.

The combination of these active ingredients in a single oral suspension allows for a multifaceted approach to treatment, addressing allergic, inflammatory, fungal, and bacterial components of disease states. This synergistic effect can enhance therapeutic outcomes, providing comprehensive relief and promoting recovery. If you have any questions or require further information, please reach out to us at Bayview Pharmacy.

Frequently Asked Questions

A small arrow pointing down

What is the purpose of this compounded oral suspension?

This compounded oral suspension is formulated to provide relief from symptoms such as inflammation, itching, and infection. It combines Diphenhydramine HCl for its antihistamine properties, Hydrocortisone for its anti-inflammatory effects, Nystatin for its antifungal action, and Tetracycline for its antibiotic properties.

How should I store this oral suspension?

Store the oral suspension in a cool, dry place away from direct sunlight. It is important to keep it out of reach of children and pets. Follow any specific storage instructions provided by your pharmacist or healthcare provider.

How do I properly administer this oral suspension?

Shake the bottle well before each use to ensure the ingredients are evenly distributed. Use a proper measuring device, such as an oral syringe or dosing cup, to ensure accurate dosing. Follow the dosage instructions provided by your healthcare provider.

Can I use this oral suspension for children?

This formulation may be used for children if prescribed by a healthcare provider. It is important to follow the specific dosing instructions provided for pediatric patients, as they may differ from adult dosages.

Are there any potential side effects of this oral suspension?

Possible side effects may include drowsiness, dizziness, upset stomach, or allergic reactions. If you experience any severe or concerning symptoms, contact your healthcare provider immediately.

Can I take this oral suspension with other medications?

Before taking this oral suspension with other medications, consult your healthcare provider or pharmacist. They can help determine if there are any potential interactions with your current medications.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How long should I continue using this oral suspension?

Use the oral suspension for the duration prescribed by your healthcare provider. Do not stop using it prematurely, even if symptoms improve, unless advised by your healthcare provider.

Is it safe to use this oral suspension during pregnancy or breastfeeding?

If you are pregnant or breastfeeding, consult your healthcare provider before using this oral suspension. They can assess the potential risks and benefits based on your specific situation.

What should I do if I experience an allergic reaction?

If you experience signs of an allergic reaction, such as rash, itching, swelling, severe dizziness, or difficulty breathing, seek immediate medical attention. Discontinue use of the oral suspension and inform your healthcare provider.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Diphenhydramine HCl 1.25 mg/mL/Hydrocortisone 0.5 mg/mL/Nystatin 20000 Units/mL/Tetracycline 12.5 mg/mL Oral Suspension
Suspension
30 mL
controlled

Take orally

Four times daily