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Formulas

Diphenhydramine HCl 1 mg/mL/Doxycycline Hyclate 2 mg/mL/Hydrocortisone 1.0 mg/mL Oral Suspension

FDA-approved generic
Dose form
Suspension
Active ingredients
Diphenhydramine Hydrochloride
Doxycycline Hyclate
Hydrocortisone

This oral suspension is a liquid dosage form where Diphenhydramine HCl, Doxycycline Hyclate, and Hydrocortisone are uniformly dispersed in a liquid medium, ensuring a homogeneous mixture for effective administration.

Formulated to treat allergic reactions, bacterial infections, and inflammatory conditions, this suspension combines the antihistamine properties of Diphenhydramine HCl, the antibiotic effects of Doxycycline Hyclate, and the anti-inflammatory benefits of Hydrocortisone.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Diphenhydramine Hydrochloride
Doxycycline Hyclate
Hydrocortisone
Suspension
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This compounded oral suspension contains Diphenhydramine HCl at a concentration of 1 mg/mL, Doxycycline Hyclate at 2 mg/mL, and Hydrocortisone at 1.0 mg/mL. These active ingredients are uniformly dispersed in a liquid medium to provide a homogeneous mixture for administration. This formulation is designed to deliver the antihistaminic, antibacterial, and anti-inflammatory effects of its constituents in a single, convenient dosage form.

Diphenhydramine HCl is an antihistamine that works by blocking histamine receptors, thereby reducing allergic symptoms such as itching, sneezing, and runny nose. It is commonly used to relieve symptoms associated with allergies, hay fever, and the common cold. By reducing histamine-mediated effects, it helps alleviate discomfort caused by allergic reactions.

Doxycycline Hyclate is a broad-spectrum tetracycline antibiotic that inhibits bacterial protein synthesis, effectively stopping the growth of bacteria. It is used to treat a variety of bacterial infections, including respiratory tract infections, skin infections, and certain types of infections that are resistant to other antibiotics. Its inclusion in this suspension allows for the treatment of bacterial infections that may be associated with inflammatory conditions.

Hydrocortisone is a corticosteroid that reduces inflammation by suppressing the immune response and decreasing the formation of substances that cause inflammation. It helps alleviate symptoms such as swelling, redness, and pain. The anti-inflammatory properties of hydrocortisone complement the effects of the other ingredients, providing comprehensive relief from both the cause and symptoms of certain conditions.

This compounded formulation may be particularly beneficial for patients who require simultaneous management of allergic reactions, bacterial infections, and inflammation. Combining these medications into a single oral suspension enhances patient compliance, especially for those who have difficulty swallowing pills, such as children or the elderly. It also allows for tailored dosing to meet specific patient needs.

Patients should take this medication exactly as prescribed by their healthcare provider. The dosage and duration of treatment depend on the medical condition and response

Drug Interactions

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This compounded oral suspension contains Diphenhydramine HCl, Doxycycline Hyclate, and Hydrocortisone, each of which can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions. It is crucial for both patients and prescribers to be aware of these interactions to ensure safe and appropriate use of this formulation.

Diphenhydramine HCl, an antihistamine, can cause sedation and drowsiness. When taken with other central nervous system depressants such as alcohol, benzodiazepines, opioids, or other sedating antihistamines, there is an increased risk of enhanced sedation and respiratory depression. Patients should be advised to avoid or limit the use of these substances while taking this formulation. Additionally, diphenhydramine may interact with monoamine oxidase inhibitors (MAOIs), potentially leading to increased anticholinergic effects such as dry mouth, urinary retention, and constipation.

Doxycycline Hyclate, a tetracycline antibiotic, can interact with antacids and supplements containing calcium, magnesium, aluminum, or iron, as these can bind to doxycycline and reduce its absorption and effectiveness. Patients should be instructed to take doxycycline at least 1-2 hours before or after consuming these products. Doxycycline may also enhance the effects of anticoagulants like warfarin, increasing the risk of bleeding. Regular monitoring of coagulation parameters is recommended when these drugs are used concurrently. Additionally, doxycycline can reduce the efficacy of oral contraceptives, so alternative or additional contraceptive measures should be considered.

Hydrocortisone, a corticosteroid, can interact with nonsteroidal anti-inflammatory drugs (NSAIDs) and increase the risk of gastrointestinal bleeding. Patients should be advised to use caution when taking NSAIDs concurrently. Hydrocortisone may also interact with certain antidiabetic medications, potentially leading to altered blood glucose levels. Patients with diabetes should monitor their blood sugar levels closely and consult their healthcare provider for any necessary adjustments to their diabetes medication regimen. Furthermore, hydrocortisone can interact with other immunosuppressive agents, potentially increasing the risk of infections.

It is important for prescribers to review the patient's current medication list for potential interactions and adjust therapy as needed. Patients should be encouraged to report any unusual symptoms or side effects to their healthcare provider promptly. If you have any questions or need further information, please reach out to us at Bayview Pharmacy.

How Does it Work

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This compounded oral suspension combines Diphenhydramine HCl, Doxycycline Hyclate, and Hydrocortisone in a liquid dosage form, ensuring a homogeneous mixture for effective administration. Each component plays a distinct role in addressing various disease states, providing a multifaceted approach to treatment.

Diphenhydramine HCl, at a concentration of 1 mg/mL, is an antihistamine that works by blocking the action of histamine, a substance in the body that causes allergic symptoms. By inhibiting histamine receptors, Diphenhydramine helps alleviate symptoms such as itching, swelling, and rashes. Its sedative properties also contribute to reducing discomfort and promoting rest, which can be beneficial in managing symptoms that disrupt sleep.

Doxycycline Hyclate, present at 2 mg/mL, is a broad-spectrum antibiotic belonging to the tetracycline class. It functions by inhibiting protein synthesis in bacteria, thereby preventing their growth and proliferation. By addressing the bacterial component of infections, Doxycycline helps reduce inflammation and prevent the spread of infection, contributing to faster recovery and symptom relief.

Hydrocortisone, included at 1.0 mg/mL, is a corticosteroid that exerts anti-inflammatory and immunosuppressive effects. It works by reducing the production of substances in the body that cause inflammation, thereby alleviating symptoms such as redness, swelling, and pain. Its inclusion in the formulation helps to quickly reduce inflammation and improve patient comfort.

The combination of these three active ingredients in a liquid suspension allows for precise dosing and easy administration, particularly beneficial for patients who may have difficulty swallowing tablets or capsules. The uniform dispersion of the ingredients ensures consistent therapeutic effects with each dose, enhancing the overall efficacy of the treatment regimen.

This formulation is designed to provide comprehensive relief by addressing multiple pathways involved in allergic reactions, bacterial infections, and inflammatory conditions. Patients and prescribers can expect a synergistic effect from the combined action of Diphenhydramine, Doxycycline, and Hydrocortisone, leading to improved outcomes and patient satisfaction. If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is the purpose of this compounded formulation?

This compounded formulation combines Diphenhydramine HCl, Doxycycline Hyclate, and Hydrocortisone to provide a multi-faceted treatment approach. Diphenhydramine HCl is an antihistamine, Doxycycline Hyclate is an antibiotic, and Hydrocortisone is a corticosteroid, which together can help manage symptoms such as allergies, infections, and inflammation.

How should I store this oral suspension?

This oral suspension should be stored in a cool, dry place away from direct sunlight. It is important to keep it at room temperature unless otherwise directed by your pharmacist or healthcare provider. Always keep the bottle tightly closed when not in use.

How do I properly administer this oral suspension?

Shake the bottle well before each use to ensure the ingredients are evenly distributed. Use a proper measuring device, such as an oral syringe or dosing cup, to ensure accurate dosing. Follow the dosage instructions provided by your healthcare provider.

Can this formulation be used for children?

The use of this formulation in children should be determined by a healthcare provider. Dosage and safety can vary based on the child's age, weight, and medical condition, so it is important to consult a healthcare professional before administering it to children.

Are there any potential side effects of this formulation?

As with any medication, there may be potential side effects. Common side effects can include drowsiness, dizziness, upset stomach, or dry mouth. If you experience severe side effects or an allergic reaction, seek medical attention immediately.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.

Can I take this formulation with other medications?

Before taking this formulation with other medications, consult your healthcare provider or pharmacist. There may be potential interactions with other drugs, which could affect the efficacy or increase the risk of side effects.

How long can I use this oral suspension?

The duration of use should be determined by your healthcare provider based on your specific condition and response to treatment. Do not use this medication for longer than prescribed without consulting your healthcare provider.

What should I do if I experience an allergic reaction?

If you experience symptoms of an allergic reaction, such as rash, itching, swelling, severe dizziness, or trouble breathing, seek immediate medical attention. Discontinue use of the medication and inform your healthcare provider.

Is it safe to use this formulation during pregnancy or breastfeeding?

The safety of this formulation during pregnancy or breastfeeding should be discussed with your healthcare provider. They will weigh the potential benefits and risks before recommending its use in these situations.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Diphenhydramine HCl 1 mg/mL/Doxycycline Hyclate 2 mg/mL/Hydrocortisone 1.0 mg/mL Oral Suspension
Suspension
30 mL
controlled

Take orally

Four times daily