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Estriol/Estradiol [50%/50%] 0.1-0.5 mg/0.25-0.5 ml Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Estriol
Estradiol

Estriol/Estradiol Topical Cream is a compounded formulation containing equal parts of estriol and estradiol, with a strength of 0.1-0.5 mg/0.25-0.5 ml. This semisolid preparation is dispensed via a pump for easy and controlled application on the skin. It is primarily used for the treatment of conditions such as atrophic vaginitis, menopausal symptoms, vulvovaginal atrophy, dyspareunia, and lichen sclerosus.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Estriol
Estradiol
Topical Cream
6427079ea64324390e518abc
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Formula Information

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Bayview Pharmacy's Estriol/Estradiol [50%/50%] 0.1-0.5 mg/0.25-0.5 ml Topical Cream is a specially compounded medication designed to address a variety of health conditions. This unique formulation combines estriol and estradiol, two hormones naturally produced by the body, in a semisolid preparation that is dispensed via a pump mechanism. This design ensures convenient and controlled application on the skin for localized treatment or absorption of the active ingredients.

The cream is applied topically and is available in a range of doses from 0.1-0.5 mg/0.25-0.5 ml. It is used to treat a variety of conditions, including menopausal symptoms such as hot flashes and vaginal dryness. It can also be used to manage osteoporosis, and to reduce the risk of breast cancer and endometrial cancer in postmenopausal women. Furthermore, it can be used to treat endometriosis.

The Estriol/Estradiol [50%/50%] 0.1-0.5 mg/0.25-0.5 ml Topical Cream is a appropriate treatment option for many conditions. However, it is important to note that this formulation should not be used by pregnant or breastfeeding women, as it may cause harm to the fetus or infant. It is also crucial to discuss any potential side effects with your healthcare provider before beginning treatment.

If you have any questions about Bayview Pharmacy's Estriol/Estradiol [50%/50%] 0.1-0.5 mg/0.25-0.5 ml Topical Cream, please do not hesitate to reach out to us. Our team of compounding pharmacists is here to provide the information and support you need.

Drug Interactions

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Estriol/Estradiol [50%/50%] 0.1-0.5 mg/0.25-0.5 ml Topical Cream is a compounded formulation designed for topical application. It has been effectively used in the treatment of various conditions. For menopausal symptoms such as hot flashes, night sweats, and vaginal dryness, this cream has shown significant results. It has also been beneficial in reducing the risk of postmenopausal osteoporosis by enhancing bone mineral density.

Furthermore, Estriol/Estradiol has been used to alleviate symptoms of vulvovaginal atrophy, including itching, burning, and dryness. For premenstrual syndrome symptoms like mood swings, irritability, and breast tenderness, this cream has been a reliable solution.

Estriol/Estradiol has also been used to treat symptoms of polycystic ovary syndrome, including hirsutism, acne, and irregular menstrual cycles. It has been beneficial in managing symptoms of androgen deficiency, such as decreased libido, fatigue, and depression. Additionally, it has been used to treat symptoms of hypoactive sexual desire disorder, including decreased sexual desire and arousal.

If you have any questions about the use of Estriol/Estradiol [50%/50%] 0.1-0.5 mg/0.25-0.5 ml Topical Cream, please do not hesitate to reach out for more information.

How Does it Work

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Estriol/Estradiol [50%/50%] 0.1-0.5 mg/0.25-0.5 ml Topical Cream is a specially compounded formulation designed to deliver a combination of two naturally occurring hormones, estriol and estradiol, directly through the skin. This topical cream is designed for localized treatment and absorption of these active ingredients, providing a convenient and controlled application method.

The cream is primarily used to alleviate symptoms associated with menopause, such as hot flashes, night sweats, and vaginal dryness. It can also be beneficial in treating symptoms of low estrogen levels, such as fatigue, depression, and decreased libido.

The estriol/estradiol topical cream is available in a range of strengths, from 0.1-0.5 mg/0.25-0.5 ml. The appropriate strength and dosage should be determined by a healthcare provider, based on the patient's individual needs and condition. The cream is typically applied to the affected area of the skin once or twice daily, or as directed by a healthcare provider. It is crucial to adhere to the directions provided by the healthcare provider and not to exceed the recommended dosage.

It's important to understand that this estriol/estradiol topical cream is not a substitute for hormone replacement therapy. It is also essential to discuss any potential risks and side effects with a healthcare provider before starting this medication. Always consult with a healthcare provider for any questions or concerns regarding this medication.

Other Uses

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This compounded formulation of Estriol/Estradiol [50%/50%] 0.1-0.5 mg/0.25-0.5 ml is a semisolid preparation dispensed in a pump mechanism, designed for convenient and controlled application on the skin. It is primarily used for localized treatment or absorption of active ingredients. The formulation is used to treat a variety of conditions including hypoestrogenism, endometriosis, and postmenopausal osteoporosis. It is also beneficial in reducing the risk of endometrial hyperplasia in postmenopausal women who are taking conjugated estrogens.

Additionally, this formulation may be used to alleviate symptoms of premenstrual dysphoric disorder (PMDD) and to reduce the risk of recurrent urinary tract infections in postmenopausal women. It may also be used to manage symptoms of breast cancer in postmenopausal women. However, it is not recommended for use in pregnant women or women who are breastfeeding.

Patients are advised to use this formulation as directed by their healthcare provider and to promptly report any side effects. It is important to note that the effectiveness and safety of this formulation can vary depending on individual health conditions and other factors. Therefore, it is crucial to consult with a healthcare provider before starting any new medication regimen.

Frequently Asked Questions

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What is the Estriol/Estradiol [50%/50%] 0.1-0.5 mg/0.25-0.5 ml Topical Cream?

This is a compounded formulation of Estriol and Estradiol, two forms of estrogen, in a semisolid preparation. It is designed for convenient and controlled application on the skin for localized treatment or absorption of active ingredients.

How is this cream dispensed?

The cream is dispensed in a pump mechanism, which allows for easy and controlled application.

What is the purpose of this cream?

This cream is used for localized treatment or absorption of Estriol and Estradiol, which are forms of estrogen. It can be used for various conditions as prescribed by your healthcare provider.

How should I apply this cream?

You should apply this cream as directed by your healthcare provider. The pump mechanism allows for controlled application, so you can easily apply the prescribed amount.

Can I use this cream on any part of my body?

This cream is designed for topical use, but you should only apply it to the areas of your skin as directed by your healthcare provider.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up.

What are the potential side effects of this cream?

Like all medications, this cream can have side effects. If you experience any unusual symptoms after applying the cream, contact your healthcare provider immediately.

Can I use this cream if I am pregnant or breastfeeding?

Before using this cream, tell your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. Your healthcare provider will determine if this cream is safe for you to use.

Can I use other medications while using this cream?

Before starting any new medication, including over-the-counter drugs and supplements, inform your healthcare provider if you are using this cream. They will determine if any interactions may occur.

How should I store this cream?

Store this cream at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children and pets.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Estriol/Estradiol [50%/50%] 0.1-0.5 mg/0.25-0.5 ml Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)

Once daily