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The Glycolic Acid 2%/Salicylic Acid 5%/Tretinoin 0.1% Topical Cream is a specially compounded semisolid preparation, which is dispensed through a pump mechanism to ensure convenient and controlled application. This formulation is designed to deliver a combination of active ingredients directly to the skin for localized treatment. Glycolic acid serves as an exfoliant, helping to remove dead skin cells and promote a more youthful appearance. Salicylic acid is a beta hydroxy acid that works to combat acne by exfoliating the skin and reducing inflammation. Tretinoin, a potent derivative of vitamin A, is known for its ability to treat acne and photoaging by promoting skin cell turnover and collagen production.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Glycolic Acid 2%/Salicylic Acid 5%/Tretinoin 0.1% Topical Cream is a specially compounded formulation designed to address a variety of dermatological conditions. This cream combines the exfoliating and keratolytic properties of glycolic acid and salicylic acid with the retinoid activity of tretinoin. Glycolic acid, an alpha hydroxy acid (AHA), helps to gently exfoliate the outer layer of the skin, promoting cell turnover and improving skin texture. Salicylic acid, a beta hydroxy acid (BHA), penetrates into the pores to dissolve sebum and dead skin cells, reducing the occurrence of clogged pores and breakouts.
The cream is formulated as a semisolid preparation and is dispensed in a pump mechanism container. This delivery system ensures a convenient, hygienic, and controlled application, minimizing waste and oxidation of the active ingredients. The pump mechanism also helps to maintain the stability of tretinoin, which can be sensitive to light and air. Patients are advised to apply the cream as directed by their healthcare provider, typically once daily in the evening, to clean, dry skin. It is important to use sunscreen during the day while using this product, as the ingredients can increase the skin's sensitivity to sunlight.
For prescribers, it is crucial to consider the patient's skin type and any pre-existing conditions before recommending this formulation. The combination of active ingredients can be potent, and some patients may experience initial irritation, redness, or peeling. These reactions are typically temporary and may subside as the skin adjusts to the treatment. Prescribers should monitor patient progress and adjust the treatment regimen as necessary to ensure optimal results and minimize potential side effects.
Bayview Pharmacy's team of compounding pharmacists is dedicated to providing high-quality, customized medications to meet the specific needs of patients. If you have any questions about this formulation or would like to discuss individual patient requirements, please do not hesitate to reach out to us. We are here to support both patients and healthcare providers in achieving the best possible therapeutic outcomes.
The topical cream formulation containing Glycolic Acid 2%, Salicylic Acid 5%, and Tretinoin 0.1% is a potent combination used for the treatment of various skin conditions such as acne, hyperpigmentation, and photoaging. When using this formulation, it is important to consider potential drug interactions that may affect the efficacy of the treatment or cause adverse effects.
Glycolic acid is an alpha hydroxy acid (AHA) that may enhance the penetration of other substances into the skin. When used with other topical agents, there is a potential for increased absorption of those agents, which could lead to irritation or other side effects. Salicylic acid is a beta hydroxy acid (BHA) that can also increase skin penetration and has similar interaction risks. Tretinoin, a retinoid, is known to be sensitive to ultraviolet (UV) light and may degrade if used with products containing benzoyl peroxide or other oxidizing agents. Concurrent use of these agents should be avoided or spaced out in application timing.
Patients should be cautious when using other topical products, such as medicated cleansers, astringents, or peeling agents, as these may increase the risk of skin irritation. Additionally, products containing alcohol or lime should be avoided as they can cause excessive dryness or irritation when used with this formulation. The use of abrasive soaps and cleansers, as well as cosmetic products with a strong drying effect, should also be limited.
Systemic interactions are less likely with topical applications; however, caution is advised when using other systemic medications that may increase sensitivity to sunlight, such as tetracyclines or thiazide diuretics, as there is an increased risk of phototoxic reactions. Patients should be advised to use sun protection and avoid unnecessary sun exposure while using this formulation.
It is important to note that the use of this formulation should be monitored by a healthcare provider, especially in patients who are pregnant, planning to become pregnant, or breastfeeding, due to the presence of tretinoin, which is a known teratogen. Patients should inform their healthcare provider of all medications they are taking, including over-the-counter drugs and herbal products, to avoid potential interactions.
For any questions or concerns regarding the use of this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is available to provide guidance and support to ensure appropriate treatment.
The Glycolic Acid 2%/Salicylic Acid 5%/Tretinoin 0.1% Topical Cream is a specially compounded formulation that combines the therapeutic effects of three active ingredients, each with a distinct mechanism of action, to treat a variety of dermatological conditions, including acne, hyperpigmentation, and photoaging. This cream is designed to be dispensed in a pump mechanism, which allows for a hygienic, convenient, and controlled application, ensuring that the correct dose is delivered with each use.
Glycolic acid, a type of alpha-hydroxy acid (AHA), works by exfoliating the skin, helping to remove dead skin cells from the surface layer. This action not only improves skin texture and tone but also promotes the regeneration of new skin cells. By increasing cell turnover, glycolic acid can also enhance the penetration of other active ingredients in the formulation.
Salicylic acid, a beta-hydroxy acid (BHA), is known for its ability to penetrate into the pores of the skin. At a 5% concentration, it acts as a keratolytic agent, breaking down the bonds between dead skin cells, and has comedolytic properties, meaning it helps to prevent and treat comedones (blackheads and whiteheads).
Tretinoin, a derivative of vitamin A, is included in this formulation at a 0.1% concentration. It is a potent retinoid that works by modulating gene expression and promoting the differentiation and proliferation of keratinocytes. This results in an increase in epidermal turnover, leading to the expulsion of mature comedones and a reduction in the formation of new acne lesions. Tretinoin also stimulates collagen production, which can help reduce the appearance of fine lines and wrinkles, making it a valuable ingredient for anti-aging treatments.
When combined, these three ingredients provide a comprehensive approach to treating acne by targeting different aspects of its pathogenesis: abnormal desquamation, sebum production, bacterial growth, and inflammation. Additionally, the formulation can help in the management of other skin conditions characterized by hyperkeratinization, such as keratosis pilaris, and in the improvement of skin texture and pigmentation issues.
Patients should be advised to apply the cream as directed by their healthcare provider, typically starting with a small amount applied to the affected area once daily at night, and to use sunscreen during the day due to increased photosensitivity. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy.
This topical cream is designed to treat a variety of skin conditions, such as acne, hyperpigmentation, and textural irregularities. The combination of glycolic acid, salicylic acid, and tretinoin works to exfoliate the skin, clear pores, promote skin cell turnover, and improve the appearance of the skin over time.
The cream should be applied once a day or as directed by your healthcare provider. Ensure your skin is clean and dry before application. Use the pump to dispense a small amount onto your fingertips and gently apply a thin layer to the affected areas, avoiding sensitive areas like the eyes, nostrils, and mouth.
Possible side effects include redness, peeling, dryness, burning, and increased sensitivity to sunlight. If you experience severe discomfort or signs of an allergic reaction, discontinue use immediately and seek medical advice.
Yes, the use of sunscreen is highly recommended. Tretinoin and hydroxy acids increase the skin's sensitivity to sunlight, thereby necessitating the use of a broad-spectrum sunscreen during the day to protect the skin from harmful UV rays.
Pregnant or breastfeeding women should not use this cream without consulting a healthcare provider as tretinoin is known to potentially cause harm to the fetus or nursing infant.
Results vary based on individual skin types and conditions; however, some users may see improvements within a few weeks, while for others it may take several months of consistent use to notice significant changes.
It is best to consult with a healthcare provider before combining this cream with other skincare products, as there may be interactions or increased skin irritation with combined use.
The cream should be stored at room temperature, away from direct sunlight and heat. The pump mechanism ensures the product remains uncontaminated by external factors, but it should still be stored properly to maintain its efficacy.
If you miss an application, apply the cream as soon as you remember. However, if it is almost time for your next scheduled application, skip the missed dose to avoid excessive application. Do not double up on applications to make up for the missed one.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
