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The Guaifenesin 10%/Ketoprofen 10%/Lidocaine 5% Transdermal Gel is a specialized semisolid formulation designed for targeted delivery of active ingredients through the skin. This unique compound combines the expectorant properties of Guaifenesin, the anti-inflammatory and analgesic effects of Ketoprofen, and the local anesthetic benefits of Lidocaine. The gel is dispensed through a pump mechanism, which ensures easy and precise application to the affected area, providing a consistent dose with each use.
This transdermal gel is primarily used to treat musculoskeletal pain and inflammation, such as that associated with arthritis, strains, and sprains. The inclusion of Guaifenesin may also aid in the management of chest congestion by facilitating mucous clearance. The Lidocaine component offers immediate topical pain relief.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Guaifenesin 10%/Ketoprofen 10%/Lidocaine 5% Transdermal Gel is a specialized medication compounded to provide symptomatic relief in various conditions. Guaifenesin, a well-known expectorant, is included in this formulation for its potential to enhance the delivery of other medications through its muscle relaxing properties when applied topically. Although traditionally used to aid in the clearance of mucus from the airways, in a transdermal application, it may assist in easing muscle tension and facilitating the deeper penetration of the other active ingredients.
Ketoprofen, a potent nonsteroidal anti-inflammatory drug (NSAID), provides the anti-inflammatory and analgesic effects necessary for the treatment of conditions such as arthritis, bursitis, and other musculoskeletal pains. By incorporating Ketoprofen into this transdermal gel, the medication can be directly applied to the site of pain or inflammation, potentially reducing systemic side effects and improving local relief.
Lidocaine, a local anesthetic, is included at a 5% concentration to provide immediate and localized pain relief by numbing the affected area. This can be particularly beneficial for patients experiencing sharp, shooting pains or those requiring a rapid onset of analgesia. The inclusion of Lidocaine also helps to improve patient comfort during the application of the gel.
The semisolid formulation is designed to be dispensed through a pump mechanism, which allows for easy and precise dosing. This delivery system ensures that the medication is applied consistently and accurately to the area of discomfort. The gel base facilitates the transdermal absorption of the active ingredients and provides a convenient, non-greasy application that can be smoothly integrated into a patient's daily routine.
This compounded medication is intended for patients who require a multimodal approach to pain management, particularly when oral medications are not suitable or have not provided adequate relief. It may also be beneficial for individuals seeking a targeted therapy with a potentially lower risk of systemic side effects. As with any medication, it is essential that it is used under the guidance of a healthcare professional who can evaluate the appropriateness of this formulation for a patient's specific condition.
For patients and prescribers interested in utilizing this Guaifenesin/Ketoprofen/Lidocaine Transdermal Gel, it is important to consider the individual components' mechanisms of action, potential side effects, and the synergistic benefits they may offer when combined in this unique formulation. If you have any questions or require further information about this compounded medication, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is committed to providing the highest level of care and support to our patients and healthcare providers.
The transdermal gel formulation containing Guaifenesin 10%, Ketoprofen 10%, and Lidocaine 5% is designed for topical application and may offer symptomatic relief for various conditions such as musculoskeletal pain, neuropathic pain, and chest congestion. Guaifenesin is an expectorant that helps loosen phlegm in the lungs and facilitate its removal, which can be beneficial in respiratory conditions with mucus buildup. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can reduce inflammation and pain in tissues. Lidocaine is a local anesthetic that provides temporary relief of pain by blocking nerve signals in the body.
When using this transdermal gel, it is important to consider potential drug interactions. Guaifenesin has a relatively low potential for significant drug interactions; however, it may interact with some drugs that affect the secretion of stomach acid, such as proton pump inhibitors or H2 antagonists, potentially altering the absorption of guaifenesin. Ketoprofen, like other NSAIDs, can interact with anticoagulants (e.g., warfarin), antiplatelet agents (e.g., aspirin), selective serotonin reuptake inhibitors (SSRIs), and other medications that increase the risk of bleeding. It may also interact with other NSAIDs, leading to an increased risk of gastrointestinal ulceration or kidney damage. Concurrent use with angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) can reduce their antihypertensive effects and increase the risk of renal impairment. Lidocaine, when applied topically, has a low risk of systemic interactions; however, caution should be exercised when used with other local anesthetics or medications that affect cardiac conduction, as there is a potential for additive effects on the heart.
Patients should be advised to inform their healthcare provider of all medications they are currently taking, including over-the-counter drugs, supplements, and herbal products, to assess for potential interactions. It is also important to use this medication as directed and to avoid applying it to broken or irritated skin, which could increase systemic absorption of the active ingredients and the risk of adverse effects. If there are any questions or concerns regarding the use of this transdermal gel or potential drug interactions, please reach out to us at Bayview Pharmacy for further assistance.
The Guaifenesin 10%/Ketoprofen 10%/Lidocaine 5% Transdermal Gel is a specially compounded medication designed to deliver active ingredients directly through the skin to the targeted area. This semisolid formulation is dispensed through a pump mechanism, which allows for easy and precise application. The gel-like consistency ensures that the medication stays where it is applied and facilitates the absorption of the active ingredients.
Guaifenesin is an expectorant commonly used to help clear mucus from the airways. However, when included in a transdermal gel, it is thought to serve a different purpose. It may help to enhance the penetration of the other active ingredients through the skin, although its exact mechanism of action in this formulation is not fully understood. This could potentially improve the overall effectiveness of the gel in treating localized musculoskeletal conditions.
Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. When applied topically, ketoprofen can provide localized relief from pain and inflammation without the systemic side effects often associated with oral NSAIDs. This makes it particularly useful for treating conditions such as arthritis, tendonitis, or other musculoskeletal pain.
Lidocaine is a local anesthetic that provides temporary relief of pain by blocking nerve signals in the body. In a transdermal gel, lidocaine can numb the targeted area, providing relief from pain associated with conditions like neuropathic pain, post-herpetic neuralgia, or other localized pain syndromes. The inclusion of lidocaine in the formulation can help to reduce discomfort upon application and improve patient compliance.
The combination of these three active ingredients in a transdermal gel allows for a multimodal approach to pain management. The gel can be applied directly to the site of pain, reducing systemic exposure and potential side effects. This formulation is particularly useful for patients who may have difficulty taking oral medications or those who prefer a targeted approach to pain management.
It is important for both patients and prescribers to understand that this compounded medication should be used as directed by a healthcare professional. The specific concentration of each ingredient has been chosen to maximize therapeutic effects while minimizing potential side effects. Patients should apply the gel as prescribed, and not exceed the recommended dose or frequency of application. If there are any questions or concerns about the use of this medication, please reach out to us at Bayview Pharmacy for further assistance.
This transdermal gel is designed to deliver active ingredients through the skin to target specific areas of the body. It can help to relieve pain, inflammation, and congestion in the tissues beneath the skin where it is applied.
Apply the gel as directed by your healthcare provider. Use the pump to dispense the medication onto your skin and gently spread it over the affected area. Wash your hands after application unless your hands are the area being treated.
The frequency of application will depend on your specific condition and the instructions provided by your healthcare provider. Do not exceed the recommended dosage.
You may cover the area with a breathable cloth if desired, but avoid using occlusive dressings unless advised by your healthcare provider.
This medication should be used in children only if prescribed by a healthcare provider. Always consult a physician before using the gel on children.
Possible side effects may include skin irritation, redness, itching, or rash at the site of application. If you experience any severe side effects or signs of an allergic reaction, contact your healthcare provider immediately.
No, do not apply the gel to open wounds, cuts, or any areas of infected, broken, or damaged skin. The gel is intended for intact skin only.
Store the gel at room temperature, away from heat and direct sunlight. Make sure the cap on the pump is securely closed to prevent the medication from drying out.
If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply double the amount to catch up.
Always inform your healthcare provider of all other medications you are taking, as there may be potential interactions. Do not use other topical preparations on the same area without medical advice.
Lidocaine, one of the active ingredients, could cause temporary numbness or other sensations that might affect your ability to perform tasks that require full sensory function. Use caution when driving or operating machinery until you know how the gel affects you.
The safety of this medication during pregnancy or breastfeeding has not been fully established. Always consult your healthcare provider before using this gel if you are pregnant, planning to become pregnant, or are breastfeeding.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
