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The Hydrocortisone 2.5%/Lidocaine 2%/Pramoxine HCL 2% Rectal Cream is a specially compounded semisolid preparation that combines the anti-inflammatory properties of hydrocortisone with the anesthetic effects of lidocaine and pramoxine HCL. This cream is designed to be dispensed from a pump mechanism, which allows for convenient and controlled application to the affected rectal area. The formulation is intended for the localized treatment of inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, including anal fissures, hemorrhoids, and other anal-rectal conditions. The combination of active ingredients works synergistically to reduce swelling, alleviate pain, and soothe itching, providing relief from discomfort associated with these disease states.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
The Hydrocortisone 2.5%/Lidocaine 2%/Pramoxine HCL 2% Rectal Cream is a compounded medication specifically formulated to provide symptomatic relief from various anorectal disorders. This cream combines the anti-inflammatory properties of hydrocortisone with the anesthetic effects of lidocaine and pramoxine HCL to alleviate discomfort, itching, swelling, and pain. Hydrocortisone, a corticosteroid, works by reducing inflammation and the immune response in the affected area. Lidocaine, a local anesthetic, numbs the site of application, providing immediate relief from pain and discomfort. Pramoxine HCL is another local anesthetic that works by blocking nerve signals in the body, further contributing to pain relief.
The semisolid preparation is designed for rectal application and is dispensed in a pump mechanism that ensures a convenient, hygienic, and controlled delivery of the medication. This dosage form is particularly beneficial for patients who require consistent and precise dosing with each application. The cream is intended for localized treatment, and the active ingredients are absorbed through the skin to exert their therapeutic effects directly at the site of discomfort.
This compounded formulation is commonly used to treat anorectal conditions such as hemorrhoids, anal fissures, and proctitis. By reducing inflammation and providing local anesthesia, it can significantly improve the quality of life for patients suffering from these conditions. The combination of active ingredients in this cream offers a multifaceted approach to treatment, addressing both the inflammation and the pain associated with anorectal disorders.
Patients and prescribers considering the use of this formulation should be aware of the potential side effects, which may include local irritation, skin atrophy with long-term use, and systemic effects if absorbed in significant amounts. It is important to follow the prescribed dosing regimen and to use the medication only as directed. As with any medication, it is crucial to discuss individual health conditions, potential drug interactions, and allergies with a healthcare provider before starting treatment.
For further information, guidance on usage, or to address any concerns regarding this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing personalized care and support to ensure the safe and appropriate use of our compounded medications.
The Hydrocortisone 2.5%/Lidocaine 2%/Pramoxine HCL 2% Rectal Cream is a compounded medication designed for the treatment of various anorectal disorders, such as hemorrhoids, anal fissures, and pruritus ani. The combination of these active ingredients provides both anti-inflammatory and anesthetic effects, which can help to reduce swelling, itching, and pain. However, it is important to consider potential drug interactions when using this formulation.
Hydrocortisone is a corticosteroid that may interact with other steroid medications, potentially increasing the risk of systemic side effects such as adrenal suppression, especially with prolonged use or application over large surface areas. Patients should inform their healthcare provider if they are taking oral corticosteroids or other topical steroids. Additionally, the use of hydrocortisone with drugs that suppress the immune system may increase the risk of infections.
Lidocaine is a local anesthetic that can interact with other local anesthetics or medications that affect cardiac conduction, such as antiarrhythmic drugs. Caution is advised when using this medication in conjunction with other drugs that can cause methemoglobinemia, a condition where the blood is unable to carry oxygen effectively. Examples include nitrates, sulfonamides, and certain antimalarials.
Pramoxine HCL is another local anesthetic that has a low risk of systemic absorption and minimal interactions. However, it should be used with caution in patients who are sensitive to local anesthetics of the amide or ester type.
It is also important to note that the absorption of topical medications can be increased if the skin barrier is compromised or when applied to mucous membranes, potentially leading to increased systemic exposure and risk of adverse effects. Patients should avoid applying other topical medications to the affected area without consulting a healthcare provider to prevent potential additive systemic absorption.
Patients should be advised to inform their healthcare providers of all medications they are currently taking, including over-the-counter drugs, herbal supplements, and vitamins, to ensure that there are no potential interactions with this rectal cream. Additionally, patients should be aware of signs and symptoms of systemic side effects, such as fatigue, weight gain, or irregular heartbeats, and seek medical attention if they occur.
For prescribers, it is crucial to review the patient's medication history for potential interactions and to monitor for any adverse effects during treatment with this formulation. If you have any questions or require further information regarding this compounded medication, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is available to provide the necessary support and guidance.
The Hydrocortisone 2.5%/Lidocaine 2%/Pramoxine HCL 2% Rectal Cream is a specially compounded formulation designed to provide symptomatic relief from various anorectal disorders. This cream combines the anti-inflammatory properties of hydrocortisone with the local anesthetic effects of lidocaine and pramoxine HCL to reduce swelling, itching, and pain.
Hydrocortisone is a corticosteroid that works by suppressing the immune response in the skin, leading to decreased inflammation and relief of itching and redness. In the context of anorectal disorders, hydrocortisone helps to reduce the swelling and inflammation of hemorrhoids and other inflammatory conditions of the anal and rectal areas.
Lidocaine is a local anesthetic that provides rapid relief from pain by blocking the transmission of pain signals along the nerves. It numbs the affected area, offering immediate comfort from painful symptoms associated with anorectal disorders such as fissures, hemorrhoids, and anal itching. Lidocaine's fast-acting nature makes it a valuable component of this rectal cream.
Pramoxine HCL is another local anesthetic that works similarly to lidocaine but has the added benefit of a longer duration of action. It helps to alleviate discomfort by numbing the skin and mucous membranes, making bowel movements less painful and reducing the urge to scratch affected areas.
The combination of these three active ingredients in a rectal cream formulation allows for a multi-faceted approach to treating anorectal disorders. The semisolid preparation is dispensed in a pump mechanism, which ensures a convenient and controlled application. This delivery system allows patients to apply the cream directly to the affected area with minimal discomfort and mess, ensuring that the active ingredients are localized to the site of inflammation and pain for maximum therapeutic effect.
This compounded rectal cream is particularly suited for patients experiencing anorectal conditions such as hemorrhoids, anal fissures, and pruritus ani. By reducing inflammation, numbing the affected area, and providing a barrier to further irritation, this cream helps to promote healing and comfort.
For optimal results, the cream should be applied as directed by a healthcare provider, usually several times a day, especially after bowel movements. It is important to follow the specific instructions provided by the prescriber to ensure safe and appropriate use of the medication. If you have any questions or require further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with your healthcare needs.
This compounded cream serves as a treatment for various rectal conditions by providing a combination of anti-inflammatory, anesthetic, and analgesic effects. It aims to reduce inflammation, alleviate pain, and soothe itching or irritation in the rectal area.
Use the cream as directed by your healthcare provider. Typically, it is applied to the affected area around the rectum up to several times a day, depending on the severity of the symptoms and medical advice. Read the instructions provided and use the pump mechanism to dispense the cream, applying a thin layer to the affected area.
Yes, it is formulated for the treatment of both external and internal hemorrhoids. However, when treating internal conditions, it is important to follow your healthcare provider's instructions regarding proper application.
Before using this medication, pregnant or breastfeeding women should consult with their healthcare provider, as the active ingredients can have potential effects on the fetus or be passed through breast milk.
As with any medication, there may be potential side effects. Common ones may include local irritation, burning sensation, or itching at the site of application. If you experience severe or persistent side effects, contact your healthcare provider immediately.
Some medications may interact with the active ingredients of this cream. It is important to discuss with your healthcare provider about any other drugs you are taking, including over-the-counter medications, to avoid potential interactions.
Store the cream at room temperature away from moisture and heat. Do not freeze the cream, and keep it out of reach of children.
If you miss a dose, apply the cream as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply double the amount to catch up.
The pump mechanism is designed to dispense a controlled amount of cream with each use, ensuring consistent application. To dispense, gently press down on the pump, and it will release a measured dose of the cream.
Although allergic reactions are rare, they can occur. Ingredients in the cream such as hydrocortisone, lidocaine, or pramoxine may cause an allergic reaction in some individuals. Signs of an allergic reaction may include hives, difficulty breathing, or swelling of the face, lips, tongue, or throat. If you experience these symptoms, seek immediate medical attention.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
