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Formulas

Ibuprofen 10% Transdermal Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Ibuprofen

The Ibuprofen 10% Transdermal Gel is a semisolid formulation designed for targeted delivery of ibuprofen through the skin. This gel is dispensed from a convenient pump mechanism, ensuring easy and precise application. The consistency of the gel allows for the ibuprofen to be absorbed at the site of application, providing localized relief from pain and inflammation. This formulation is commonly used to treat disease states such as arthritis, tendinitis, and other musculoskeletal conditions characterized by pain and swelling. It offers an alternative to oral administration of ibuprofen, potentially reducing systemic side effects and focusing therapy on the affected area.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Ibuprofen
Topical Gel
65aecdca0ef8a1b4899da571
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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The Ibuprofen 10% Transdermal Gel is a specialized medication designed for targeted delivery of ibuprofen through the skin. This semisolid formulation is dispensed from a pump mechanism, which ensures that patients can apply a consistent and precise dose to the affected area. The gel base provides a convenient medium for the ibuprofen to be absorbed transdermally, offering an alternative to oral administration for those who may experience gastrointestinal side effects or have difficulty swallowing pills.

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, substances in the body that mediate inflammation and pain. By applying the gel topically, the drug can act directly at the site of inflammation or pain. This localized approach can lead to reduced systemic exposure and potentially fewer side effects compared to oral ibuprofen. The 10% concentration allows for sufficient drug delivery to the affected tissues for the relief of symptoms associated with conditions such as osteoarthritis, rheumatoid arthritis, mild to moderate musculoskeletal pain, and sports-related injuries.

Patients should be advised to apply the gel as directed by their healthcare provider, typically to clean, intact skin over the affected area. It is important to avoid contact with eyes, mucous membranes, and open wounds. The use of the pump dispenser facilitates easy application and minimizes the risk of contamination. Prescribers should consider the patient's overall medication profile to avoid potential drug interactions, particularly with other NSAIDs or anticoagulants. Monitoring for local skin reactions or systemic side effects is recommended, although the risk is generally lower with topical versus systemic administration.

For patients and prescribers interested in using this Ibuprofen 10% Transdermal Gel formulation, Bayview Pharmacy's team of compounding pharmacists can provide additional information and guidance tailored to individual needs. We are committed to ensuring the safe and appropriate use of this medication. If you have any questions or require further assistance, please do not hesitate to reach out to us.

Drug Interactions

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Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. When formulated as a 10% transdermal gel, it is designed for topical application and can be used to treat localized conditions such as muscle pain, arthritis, and other inflammatory disorders. However, even though the systemic absorption of ibuprofen through the skin is lower compared to oral administration, there is still potential for drug interactions, particularly with other NSAIDs, anticoagulants, antiplatelet agents, and certain antihypertensives.

Patients using ibuprofen transdermal gel should be cautious if they are also taking oral NSAIDs (like aspirin, naproxen, or other over-the-counter pain relievers) as the combined effect can increase the risk of gastrointestinal bleeding and ulceration. Concurrent use with anticoagulants (such as warfarin) or antiplatelet agents (like clopidogrel) may also enhance the risk of bleeding. It is important to monitor for signs of bleeding and consult a healthcare provider if such symptoms occur.

Additionally, ibuprofen can attenuate the antihypertensive effects of drugs like ACE inhibitors, angiotensin receptor blockers (ARBs), beta-blockers, and diuretics. Patients on such medications should be monitored for changes in blood pressure and kidney function. Ibuprofen may also interact with selective serotonin reuptake inhibitors (SSRIs), increasing the risk of gastrointestinal bleeding. Patients should be advised to watch for signs of bleeding, including in the stool or vomit, and report any unusual symptoms to their healthcare provider.

Patients with a history of heart disease or stroke should use ibuprofen with caution, as NSAIDs can increase the risk of heart attack or stroke. This is particularly important for those taking low-dose aspirin for cardioprotection, as ibuprofen can interfere with aspirin's beneficial effects when they are used concomitantly.

It is also important to consider the potential for skin reactions. Although rare, NSAIDs can cause serious skin adverse reactions such as exfoliative dermatitis, Stevens-Johnson Syndrome (SJS), and toxic epidermal necrolysis (TEN), which can be fatal. Patients should be informed about the signs of serious skin reactions, and use of the product should be discontinued at the first appearance of skin rash or any other sign of hypersensitivity.

Lastly, patients with renal impairment should use ibuprofen with caution, as NSAIDs can worsen renal function. Regular monitoring of renal function is recommended for these patients.

As with any medication, it is crucial to use ibuprofen transdermal gel as directed and to consult with a healthcare provider before starting any new medications, including over-the-counter drugs or herbal supplements. If you have any questions or concerns about using this formulation or potential drug interactions, please reach out to us at Bayview Pharmacy for personalized advice and support.

How Does it Work

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The Ibuprofen 10% Transdermal Gel is a specially designed medication that delivers the active ingredient, ibuprofen, directly through the skin to the site of pain or inflammation. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the production of prostaglandins, which are chemicals that promote inflammation, pain, and fever. When applied topically, the ibuprofen in the gel is absorbed through the skin, where it then enters the underlying tissues to exert its anti-inflammatory and analgesic effects locally.

This transdermal delivery system offers several advantages. Firstly, it minimizes systemic absorption, which can reduce the risk of systemic side effects commonly associated with oral NSAIDs, such as gastrointestinal irritation or cardiovascular risks. Thirdly, the gel formulation is designed to enhance the penetration of ibuprofen through the skin barrier, ensuring that an adequate amount of the drug reaches the affected tissues.

The semisolid formulation of the Ibuprofen 10% Transdermal Gel is dispensed through a pump mechanism, which allows for easy and precise dosing. Patients can apply the gel directly to the affected area, ensuring targeted treatment. The gel-like consistency provides a cooling sensation upon application and is designed to be non-greasy and quick-absorbing, offering convenience and comfort to the patient.

This formulation is particularly useful for treating localized musculoskeletal conditions such as arthritis, sprains, strains, and other soft tissue injuries. By applying the gel to the affected area, patients can experience relief from pain and reduction in swelling and inflammation.

For patients and prescribers considering the use of Ibuprofen 10% Transdermal Gel, it is essential to understand the proper application technique, dosing frequency, and duration of treatment to achieve optimal results. Additionally, patients should be advised to avoid applying the gel to broken or irritated skin, and to wash their hands thoroughly after application to prevent accidental transfer of ibuprofen to the eyes or mucous membranes.

If you have any questions about the Ibuprofen 10% Transdermal Gel or its suitability for treating specific conditions, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and guidance you need to ensure appropriate treatment for your patients.

Frequently Asked Questions

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What is Ibuprofen 10% Transdermal Gel?

Ibuprofen 10% Transdermal Gel is a topical medication designed for pain relief. It consists of a 10% concentration of ibuprofen, an anti-inflammatory drug, which is delivered through the skin to target specific areas of pain or inflammation.

How do I use the Ibuprofen Transdermal Gel?

To use the gel, apply a small amount to the affected area using the pump mechanism provided. The gel should be spread evenly and gently massaged into the skin over the area of pain or inflammation.

Is Ibuprofen 10% Transdermal Gel suitable for everyone?

People with a history of allergies to ibuprofen or other NSAIDs, as well as pregnant women, especially in their third trimester, should avoid using this product. Always consult with a healthcare provider before starting any new medication.

How often can I apply the Ibuprofen Transdermal Gel?

The recommended frequency of application will be provided by your healthcare provider, but it is generally used up to four times a day. Do not exceed the recommended dose without consulting a healthcare professional.

Can I use Ibuprofen Transdermal Gel with other medications?

Care should be taken when using this gel with other medications, especially other NSAIDs or blood thinners. Always inform your healthcare provider of all medications you are currently taking to avoid potential drug interactions.

Does the Ibuprofen Transdermal Gel have any side effects?

Some common side effects include skin irritation or a burning sensation at the application site. If you experience any severe side effects or signs of an allergic reaction, such as difficulty breathing or facial swelling, seek immediate medical attention.

How should I store the Ibuprofen Transdermal Gel?

Store the gel at room temperature, away from direct sunlight and heat sources. Keep the cap tightly closed when not in use. Make sure it is out of reach of children and pets.

What should I do if I miss a dose?

If you forget to apply a dose, apply it as soon as you remember. However, if it is close to the time for your next application, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

Can I cover the area with a bandage after applying the Ibuprofen Transdermal Gel?

It is generally recommended not to cover the treated area with airtight dressings such as bandages unless advised by a healthcare provider, as this could potentially increase the absorption of ibuprofen through the skin.

What should I do if I accidentally ingest the Ibuprofen Transdermal Gel?

Although this medication is intended for external use only, if swallowed, seek immediate medical attention or contact a Poison Control Center. It is important to keep this and all medications out of the reach of children to prevent accidental ingestion.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Ibuprofen 10% Transdermal Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily