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The Lidocaine HCl 2%/Metronidazole 2%/Misoprostol 0.0024% Topical Ointment is a specialized semi-solid formulation designed for external application to the skin. This ointment is dispensed in a tube and provides a greasy or oily base, which facilitates the localized delivery of its active ingredients. Lidocaine HCl acts as a local anesthetic, providing temporary relief from pain and discomfort. Misoprostol is included for its ability to promote healing, particularly in wound care. This combination makes the ointment suitable for the treatment of various disease states, including skin inflammation, infections, and aiding in the healing of wounds.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Lidocaine HCl 2%/Metronidazole 2%/Misoprostol 0.0024% Topical Ointment is a compounded medication specifically designed for external application to the skin. This semi-solid formulation is dispensed in a tube and provides a greasy or oily base, which not only facilitates the application but also enhances the delivery and absorption of the active ingredients into the localized area of treatment. The ointment is intended for use in various dermatological conditions that may benefit from the combined effects of its active components.
Lidocaine HCl, a local anesthetic, is included at a 2% concentration to provide temporary relief of pain and discomfort by numbing the affected area. It is particularly useful in conditions where pain is a significant symptom, such as in skin inflammations or after minor surgical procedures. Metronidazole, also at a 2% concentration, is an antibiotic and antiprotozoal medication that helps to treat and prevent bacterial infections on the skin.
Misoprostol, present at a 0.0024% concentration, is a synthetic prostaglandin E1 analog. Although it is commonly known for its gastrointestinal protective properties and use in the prevention of nonsteroidal anti-inflammatory drug (NSAID)-induced ulcers, in this topical formulation, it may aid in the healing of wounds and promote tissue repair by its action on local blood flow and inflammation. The inclusion of misoprostol in this ointment could be particularly beneficial in wound healing processes, potentially reducing the time required for skin recovery.
This combination ointment is tailored for patients who require a multifaceted approach to skin care, addressing pain, infection, and promoting healing simultaneously. It is important for prescribers to consider the individual components and their actions when recommending this formulation, ensuring it aligns with the patient's specific condition and treatment goals. As with any compounded medication, it is essential to use this ointment under the guidance of a healthcare professional, and it should be applied as directed to the affected area.
Patients should be advised of the potential side effects of each active ingredient, such as local skin reactions to lidocaine or metronidazole, and systemic absorption, although minimal, should be considered, especially in the case of misoprostol. It is also important to discuss any known allergies to the active ingredients or the ointment base, as well as any other medications the patient is currently taking that may interact with the topical treatment.
For more detailed information or if you have any questions regarding this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is committed to providing personalized care and is available to assist with any inquiries or concerns you may have about this specialized medication.
The Lidocaine HCl 2%/Metronidazole 2%/Misoprostol 0.0024% Topical Ointment is a unique compound that combines the local anesthetic effects of lidocaine, the antimicrobial properties of metronidazole, and the tissue-protective effects of misoprostol. While this formulation is designed for topical application and is expected to have minimal systemic absorption, it is important to consider potential drug interactions, especially in patients who may be using other medications or have underlying health conditions.
Lidocaine, as a local anesthetic, may interact with other local anesthetics or medications that affect cardiac conduction. Caution should be exercised when using this medication in conjunction with antiarrhythmic drugs such as amiodarone or sotalol. Additionally, lidocaine metabolism may be affected by CYP3A4 inhibitors such as ketoconazole or macrolide antibiotics, potentially increasing the risk of systemic lidocaine toxicity.
Metronidazole, an antibiotic and antiprotozoal, can interact with alcohol, leading to a disulfiram-like reaction characterized by nausea, vomiting, and flushing. Patients should be advised to avoid alcohol during treatment and for at least 48 hours after the last application. Metronidazole may also potentiate the effects of anticoagulants like warfarin, increasing the risk of bleeding. Monitoring of prothrombin time or INR is recommended in patients taking warfarin concurrently.
Misoprostol is a prostaglandin analogue that may interact with other prostaglandins or prostaglandin inhibitors. Caution is advised when using this medication alongside nonsteroidal anti-inflammatory drugs (NSAIDs), as NSAIDs can reduce the efficacy of misoprostol. Additionally, misoprostol should be used with caution in pregnant women due to its potential to induce uterine contractions and cause miscarriage.
It is important to note that while systemic absorption of these agents is expected to be low when applied topically, the possibility of systemic effects cannot be entirely ruled out, especially in cases of overuse or application to large surface areas of the skin. Patients should be instructed to use the ointment as directed and report any adverse effects or unusual symptoms to their healthcare provider.
This formulation is used for the localized treatment of various skin conditions. Lidocaine provides symptomatic relief from pain by blocking nerve signals in the area where it is applied. Misoprostol helps to protect the skin and mucous membrane tissue, promoting healing and preventing ulcer formation.
Patients and prescribers should be aware of the potential for drug interactions with this compound and consider the patient's overall medication regimen and health status when prescribing or using this ointment. If you have any questions or require further information regarding this formulation and its use, please reach out to us at Bayview Pharmacy for assistance.
The Lidocaine HCl 2%/Metronidazole 2%/Misoprostol 0.0024% Topical Ointment is a specially compounded medication designed to provide targeted relief and treatment for various skin conditions. This semi-solid formulation is dispensed in a tube and is intended for external application to the skin. The ointment base is greasy or oily, which not only facilitates the delivery of the active ingredients to the affected area but also provides a protective barrier that can aid in the healing process.
Lidocaine HCl, or Lidocaine Hydrochloride, is a local anesthetic that works by blocking nerve signals in the body. When applied topically, it helps to numb the skin and surrounding tissue, providing relief from pain and discomfort. This can be particularly beneficial in conditions where skin inflammation or wounds cause pain.
In this topical formulation, Metronidazole helps to treat skin infections by disrupting the DNA and inhibiting the nucleic acid synthesis of the bacteria, leading to their death. This can help to reduce infection and inflammation, promoting a healthier healing environment for the skin.
Misoprostol is a medication that is commonly used to prevent stomach ulcers, but it also has properties that can aid in wound healing. When included in a topical ointment, Misoprostol can help to increase blood flow to the area, promoting the healing process. Additionally, it has anti-inflammatory effects that can further aid in reducing swelling and discomfort at the site of application.
The combination of these three active ingredients in the Lidocaine HCl 2%/Metronidazole 2%/Misoprostol 0.0024% Topical Ointment provides a multi-faceted approach to treating skin conditions. The Lidocaine offers pain relief, the Metronidazole addresses bacterial infections, and the Misoprostol promotes healing and reduces inflammation. This makes the ointment particularly suitable for treating conditions such as skin infections, inflammatory skin disorders, and wounds that require a conducive environment for healing.
It is important for patients and prescribers to understand that this formulation should be used as directed by a healthcare professional, and it is essential to follow the specific instructions for application and duration of treatment. If you have any questions or require further information about this compounded medication, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you with your healthcare needs.
This compounded ointment is typically used for the localized treatment of skin conditions where both pain relief and healing are desired. It may be used for skin inflammation, infections, or aiding wound healing due to the combined effects of the active ingredients.
Apply a thin layer to the affected area as directed by your healthcare provider. Ensure that the skin is clean before application. Do not cover with a bandage unless advised by your physician.
No, this compounded ointment is meant for external use only. Do not apply internally or ingest.
As with any medication, side effects are possible. Common side effects may include local irritation, itching, or redness at the application site. If you experience any severe side effects or signs of an allergic reaction, contact your healthcare provider immediately.
The frequency of application will be determined by your healthcare provider based on your specific condition. Follow their instructions closely and do not apply more often than recommended.
If you miss a dose, apply the ointment as soon as you remember. If it is close to the time of your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to catch up.
Always consult with your healthcare provider before combining medications. They will advise whether it is safe to use this ointment with other topical products.
Store the ointment at room temperature away from light and moisture. Keep the tube tightly closed when not in use. Do not store in the bathroom and keep all medications out of reach of children and pets.
The active ingredients in the ointment are Lidocaine HCl, a local anesthetic that provides pain relief; Metronidazole, an antibiotic that treats bacterial infections; and Misoprostol, which promotes healing and helps prevent ulcers.
The safety of this ointment during pregnancy has not been established. It is essential to consult with your healthcare provider to weigh the potential benefits and risks before using this medication.
Before applying the ointment on broken or severely irritated skin, it is crucial to consult with your healthcare provider as they may need to assess the condition of your skin to determine if this medication is appropriate for use.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
