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Metronidazole 10% Zinc Oxide 2% Topical Gel is a semisolid formulation designed for easy and precise application on the skin, utilizing a convenient pump mechanism. This gel-like consistency ensures targeted treatment and effective absorption of active ingredients.
This formulation is primarily used to treat skin conditions such as rosacea, acne, and other inflammatory dermatoses. The combination of metronidazole, an antimicrobial agent, and zinc oxide, known for its soothing and protective properties, helps reduce inflammation, redness, and irritation associated with these conditions.
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
Metronidazole 10% Zinc Oxide 2% Topical Gel is a compounded formulation designed for targeted application on the skin, utilizing a pump mechanism for precise dosing. This formulation is primarily used for the treatment of dermatological conditions such as rosacea, acne, and other inflammatory skin disorders. Metronidazole, an antibiotic and antiprotozoal agent, works by reducing inflammation and bacterial growth on the skin, while zinc oxide acts as a skin protectant and anti-inflammatory agent, providing a soothing effect and promoting healing.
When considering drug interactions for this topical formulation, it is important to note that systemic absorption of metronidazole from topical application is generally low. However, caution should be exercised when using this gel in conjunction with other topical or systemic medications. Patients and prescribers should be aware of the potential for interactions with other topical agents that may alter the skin's barrier function, such as exfoliants or other medicated creams, which could potentially increase the absorption of metronidazole.
Systemic interactions are less likely but should not be entirely disregarded. Metronidazole, when absorbed systemically, can interact with alcohol, leading to a disulfiram-like reaction characterized by flushing, nausea, and vomiting. Although the risk is minimal with topical use, patients should be advised to avoid alcohol consumption during treatment. Additionally, metronidazole may potentiate the anticoagulant effect of warfarin and other coumarin anticoagulants, increasing the risk of bleeding. Patients on anticoagulant therapy should be monitored closely if using this topical gel.
There is also a potential interaction with lithium, as metronidazole can increase lithium levels, leading to toxicity. Patients on lithium therapy should have their serum lithium levels monitored if they are using this topical formulation. Furthermore, caution is advised when using this gel in combination with other medications that may cause photosensitivity, as zinc oxide can enhance the skin's sensitivity to sunlight, potentially increasing the risk of sunburn.
For prescribers, it is crucial to review the patient's current medication regimen, including over-the-counter products and supplements, to identify any potential interactions. Patients should be instructed to report any unusual skin reactions or systemic symptoms promptly. If you have any questions or require further information regarding this formulation and its potential interactions, please reach out to us at Bayview Pharmacy. We are here to assist you in ensuring appropriate treatment for your patients.
The Metronidazole 10% Zinc Oxide 2% Topical Gel is a carefully compounded semisolid formulation designed to deliver targeted treatment through a convenient pump mechanism. This formulation combines the antimicrobial properties of metronidazole with the protective and soothing effects of zinc oxide. The gel-like consistency ensures that the active ingredients are evenly distributed across the affected area, promoting optimal absorption and efficacy.
Metronidazole is a nitroimidazole antibiotic that works by inhibiting the nucleic acid synthesis of bacteria and protozoa, effectively reducing inflammation and infection in the skin. By reducing the bacterial load and inflammation, metronidazole helps to alleviate symptoms such as redness, swelling, and discomfort.
Zinc oxide, on the other hand, is a mineral that provides a protective barrier on the skin. It is known for its soothing and anti-inflammatory properties, which help to calm irritated skin and promote healing. Zinc oxide also acts as a mild astringent, reducing excess oil and moisture on the skin's surface, which can be beneficial in managing conditions like diaper rash, minor abrasions, and other forms of dermatitis. Its inclusion in the formulation enhances the overall therapeutic effect by providing additional protection and comfort to the affected area.
The semisolid gel formulation is dispensed through a pump mechanism, allowing for precise and controlled application. This ensures that the correct amount of medication is delivered to the skin, minimizing waste and maximizing therapeutic outcomes. The gel's consistency allows for easy spreading and absorption, ensuring that the active ingredients penetrate effectively to exert their beneficial effects.
For patients and prescribers considering this formulation, it is important to understand the dual action of metronidazole and zinc oxide in addressing both the microbial and inflammatory components of skin conditions. This combination not only targets the underlying causes of the condition but also provides symptomatic relief, making it a comprehensive treatment option. As always, if you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy. We are here to assist you with any inquiries you may have.
This topical gel is used for targeted treatment of skin conditions, leveraging the antibacterial properties of Metronidazole and the protective benefits of Zinc Oxide to reduce inflammation and promote healing.
Dispense a small amount of the gel through the pump mechanism and apply it directly to the affected area of the skin. Gently rub it in until fully absorbed.
Follow your healthcare provider's instructions regarding frequency of use. Typically, it may be applied once or twice daily, but your specific regimen may vary.
Yes, this gel can be used on the face, but avoid contact with the eyes, mouth, and other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
Some users may experience mild skin irritation, redness, or dryness. If you experience severe reactions or persistent irritation, discontinue use and consult your healthcare provider.
Consult your healthcare provider before using this gel if you are pregnant or breastfeeding to ensure it is safe for your specific situation.
Yes, but it is advisable to apply this gel first and allow it to fully absorb before applying other products. Consult your healthcare provider for specific recommendations.
Store the gel at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.
This gel is generally suitable for most skin types, but individuals with sensitive skin should perform a patch test before full application to ensure no adverse reactions occur.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)
