Check out our most popular compounded medications! Get Started
Dashboard
Formulas

Amitriptyline 3%/Gabapentin 3%/Lidocaine 5% Transdermal Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Amitriptyline Hydrochloride
Gabapentin
Lidocaine Hydrochloride

This formulation is a combination of Amitriptyline 3%, Gabapentin 3%, and Lidocaine 5% in a transdermal gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is designed to treat various disease states. Amitriptyline, a tricyclic antidepressant, is used to manage chronic pain conditions, including neuropathic pain. Gabapentin, an anticonvulsant, is also used for pain management, particularly in conditions like postherpetic neuralgia and diabetic neuropathy. Lidocaine, a local anesthetic, provides immediate relief from pain and discomfort by numbing the affected area.

View more
For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Get started as a patient
Get Started
This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
Check if we ship to your state
No prescription yet?

Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Amitriptyline Hydrochloride
Gabapentin
Lidocaine Hydrochloride
Topical Gel
65302371f72d137c7b4e5526
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

Check your state

Available in

Tap a state to check it.

Our current service area

Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

Select a state on the map or use the checker.

Formula Information

A small arrow pointing down

This formulation combines three active ingredients: Amitriptyline, Gabapentin, and Lidocaine, each at different concentrations. Amitriptyline is a tricyclic antidepressant that is often used in pain management for conditions such as neuropathic pain. It works by increasing the levels of certain chemicals in the brain that help elevate mood and reduce the sensation of pain.

Gabapentin is an anticonvulsant that is also used to manage various forms of chronic pain, particularly neuropathic pain. It works by stabilizing electrical activity in the brain and affecting the way the nerves send messages to the brain about pain.

Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It is used to relieve pain and discomfort from various conditions such as skin irritations and minor burns.

The combination of these three ingredients in a transdermal gel allows for targeted treatment of specific areas of the body. The gel is dispensed through a pump mechanism, which allows for easy and precise application. The transdermal delivery system allows for the active ingredients to be absorbed directly through the skin, providing localized relief from pain and discomfort.

This formulation is particularly useful in treating disease states that involve chronic or neuropathic pain, such as postherpetic neuralgia, diabetic neuropathy, and fibromyalgia. It can also be used to manage pain from minor skin irritations and burns.

As with any medication, it is important to use this formulation as directed by a healthcare provider. Potential side effects may include skin irritation at the application site, dizziness, drowsiness, or changes in mood or behavior. If any of these side effects persist or worsen, or if you experience any other unusual symptoms, contact your healthcare provider immediately.

If you have any questions about this formulation, its uses, or its potential side effects, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

A small arrow pointing down

This formulation combines three active ingredients: Amitriptyline, Gabapentin, and Lidocaine, each with its own mechanism of action and potential for drug interactions. It is important to consider these interactions when prescribing or using this medication.

Amitriptyline is a tricyclic antidepressant that works by increasing the levels of certain chemicals in the brain that help improve mood, sleep, and pain. It can interact with a number of medications including MAO inhibitors, SSRIs, anticholinergics, and certain antihypertensives. These interactions can lead to serious side effects such as serotonin syndrome, increased heart rate, and elevated blood pressure. It is also important to avoid alcohol while using this medication as it can increase drowsiness and dizziness.

Gabapentin is an anticonvulsant and nerve pain medication. It can interact with antacids containing aluminum or magnesium, as they can decrease the absorption of gabapentin and reduce its effectiveness. It is also advised to avoid alcohol while on this medication as it can increase the risk of side effects such as drowsiness and dizziness.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. It has fewer drug interactions, but it can interact with certain heart medications and other local anesthetics. It is important to inform your healthcare provider if you are taking any heart rhythm medication as lidocaine can affect heart function.

This formulation is primarily used for the management of neuropathic pain conditions. Amitriptyline and Gabapentin work by changing the way the body senses pain, while Lidocaine provides local numbing effect. This combination can provide significant relief for conditions such as post-herpetic neuralgia, diabetic neuropathy, and other nerve-related pain conditions.

It is crucial to inform your healthcare provider of all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements, to avoid potential drug interactions. Also, inform your healthcare provider if you have any existing medical conditions as this can affect how the medication works and its safety.

If you have any questions or concerns about this medication, its use, or potential interactions, please do not hesitate to reach out to us.

How Does it Work

A small arrow pointing down

The Amitriptyline 3%/Gabapentin 3%/Lidocaine 5% Transdermal Gel is a unique formulation that combines three active ingredients, each with its own mechanism of action, to provide targeted relief from various disease states. This formulation is designed to be applied topically, directly to the skin, where it can be absorbed into the body to exert its therapeutic effects.

Amitriptyline is a tricyclic antidepressant that works by increasing the levels of certain chemicals in the brain that help improve mood, relieve pain, and promote sleep. In this formulation, it is used for its analgesic properties to help manage chronic pain conditions.

Gabapentin is an anticonvulsant that is often used to treat seizures and nerve pain. It works by affecting the way the nerves send messages to the brain, thereby reducing the sensation of pain. In this formulation, it is used to help manage neuropathic pain and provide relief from conditions such as postherpetic neuralgia and diabetic neuropathy.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. It is used to reduce pain or discomfort caused by skin irritations such as sunburn, insect bites, poison ivy, poison oak, poison sumac, and minor cuts, scratches, or burns. In this formulation, it provides immediate, localized relief from pain and discomfort.

The gel formulation allows for easy and precise application of the medication directly to the affected area. This targeted approach helps to maximize the therapeutic effects of the active ingredients while minimizing potential side effects. The gel is also designed to be absorbed quickly and efficiently into the skin, providing rapid relief from symptoms.

It's important to note that while this formulation can provide significant relief from various disease states, it should be used as part of a comprehensive treatment plan under the guidance of a healthcare provider. Always follow the prescribed dosage and application instructions to ensure the safe and appropriate use of this medication.

If you have any questions about the Amitriptyline 3%/Gabapentin 3%/Lidocaine 5% Transdermal Gel, or if you would like more information about how it works, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Frequently Asked Questions

A small arrow pointing down

What is this formulation: Amitriptyline 3%/Gabapentin 3%/Lidocaine 5% Transdermal Gel?

This is a semisolid formulation that contains Amitriptyline, Gabapentin, and Lidocaine. These substances are mixed in a gel-like consistency that is dispensed through a pump mechanism for ease of application and targeted treatment.

How do I use this transdermal gel?

Apply a thin layer of the gel to the affected area of skin as directed by your healthcare provider. The pump mechanism makes it easy to dispense just the right amount for each application.

What should I do if I miss a dose?

If you miss a dose, apply the gel as soon as you remember. However, if it is close to the time of your next dose, skip the missed dose and resume your regular dosing schedule. Do not apply more gel to try to make up for a missed dose.

What should I do in case of an overdose?

In case of an overdose, immediately get medical help or contact a Poison Control Center. Symptoms of overdose may include severe drowsiness, seizures, rapid or slow heartbeat, and difficulty breathing.

What are the potential side effects?

Common side effects can include redness, itchiness, or irritation at the application site. Some people may also experience drowsiness or dizziness. Please seek medical attention if these persist or if any severe side effects occur.

Can I use the gel if I have known allergies?

Do not use this product if you have known allergies to Amitriptyline, Gabapentin, or Lidocaine. Stop use and seek immediate assistance if you experience symptoms like body rash, difficulty breathing, or swelling of the face, tongue, or throat.

Are there other medications I should avoid while using this gel?

Before starting this medication, inform your healthcare provider about all the other medications you're taking. Certain medications can interact with the active ingredients, causing undesirable effects.

Why does the formulation contain three active ingredients?

Each ingredient serves a different therapeutic purpose. Amitriptyline is an antidepressant, Gabapentin is an anti-epileptic drug also used to relieve nerve pain, and Lidocaine is a local anesthetic. Together, they help to manage various symptoms more effectively.

Can I use this gel while pregnant?

Consult your healthcare provider before using this gel if you are pregnant, planning to become pregnant, or are breastfeeding. These active ingredients may affect your infant.

How should I store this formulation?

Store this medication at room temperature, away from heat and light. Keep it out of the reach of children and pets. Do not freeze. Discard when no longer needed or expired.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Amitriptyline 3%/Gabapentin 3%/Lidocaine 5% Transdermal Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily