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Carbamazepine 4%/Doxepin 4%/Gabapentin 4%/Ketoprofen 4%/Lidocaine 1% Transdermal Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Carbamazepine
Gabapentin
Ketoprofen
Doxepin Hydrochloride
Lidocaine Hydrochloride

This formulation is a combination of Carbamazepine 4%, Doxepin 4%, Gabapentin 4%, Ketoprofen 4%, and Lidocaine 1% in a transdermal gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is designed to treat a variety of disease states. Carbamazepine is an anticonvulsant and mood stabilizer, used primarily in the treatment of epilepsy and bipolar disorder. Doxepin is a tricyclic antidepressant that can also help reduce anxiety and insomnia. Gabapentin is used to treat nerve pain and seizures. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain, swelling, and inflammation. Lastly, Lidocaine is a local anesthetic that causes temporary numbness or loss of sensation in the area of application.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Carbamazepine
Gabapentin
Ketoprofen
Doxepin Hydrochloride
Lidocaine Hydrochloride
Topical Gel
65383c684dae7fb8422dc375

Formula Information

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This formulation is a combination of Carbamazepine, Doxepin, Gabapentin, Ketoprofen, and Lidocaine, all of which are active ingredients with distinct therapeutic properties. The formulation is designed as a transdermal gel, which is a semi-solid preparation that can be easily applied to the skin. The gel is dispensed through a pump mechanism, which allows for precise application and targeted treatment.

Carbamazepine is an anticonvulsant and mood stabilizer, often used in the treatment of epilepsy and bipolar disorder. In this formulation, it can help to manage nerve pain. Doxepin is a tricyclic antidepressant that can help to alleviate symptoms of depression and anxiety. It also has analgesic properties, making it useful in the management of chronic pain conditions.

Gabapentin is an anticonvulsant and nerve pain medication, often used in the treatment of seizures and neuropathic pain. In this formulation, it can help to manage nerve pain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can help to reduce inflammation and pain. Lidocaine is a local anesthetic that can help to numb the area where the gel is applied, providing immediate relief from pain.

This formulation is designed to be applied directly to the skin, allowing for targeted treatment. The active ingredients are absorbed through the skin, providing localized relief from pain and inflammation. This can be particularly beneficial for patients with conditions such as neuropathic pain, arthritis, and other chronic pain conditions.

It's important to note that this formulation should be used under the guidance of a healthcare provider. Patients should follow the prescribed dosage and application instructions to ensure the safe and appropriate use of this medication. Side effects can occur, including skin irritation, dizziness, and drowsiness. If you experience any adverse effects, contact your healthcare provider immediately.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to provide you with the information and support you need.

Drug Interactions

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This formulation contains a combination of Carbamazepine, Doxepin, Gabapentin, Ketoprofen, and Lidocaine. Each of these medications has a unique mechanism of action and potential for drug interactions. It's important to note that this is a transdermal gel, meaning it's applied to the skin and absorbed into the body. This can potentially reduce some systemic drug interactions, but it doesn't eliminate them entirely.

Carbamazepine is an anticonvulsant and mood stabilizer. It can interact with a wide range of medications, including other anticonvulsants, certain antibiotics, antifungal medications, and some antidepressants. It can also interact with grapefruit juice. These interactions can increase the risk of side effects or reduce the effectiveness of Carbamazepine or the interacting drug.

Doxepin is a tricyclic antidepressant. It can interact with other antidepressants, certain antipsychotics, and medications that affect serotonin levels. These interactions can increase the risk of a potentially life-threatening condition called serotonin syndrome. Doxepin can also interact with certain heart medications and can increase the effects of alcohol.

Gabapentin is an anticonvulsant and nerve pain medication. It can interact with antacids, reducing the absorption of Gabapentin. It can also increase the effects of certain pain medications and can increase the risk of side effects if used with other central nervous system depressants, including alcohol.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It can interact with other NSAIDs, increasing the risk of gastrointestinal side effects. It can also interact with certain blood pressure medications, reducing their effectiveness. Ketoprofen can increase the risk of bleeding if used with anticoagulants or antiplatelet drugs.

Lidocaine is a local anesthetic. It has fewer drug interactions than the other medications in this formulation, but it can interact with certain heart medications and can increase the effects of other local anesthetics.

This formulation is used to treat a variety of conditions, including nerve pain, inflammation, and certain types of depression and seizures. The combination of medications works together to target these conditions at multiple levels, providing more comprehensive relief than a single medication could. However, because of the potential for drug interactions, it's important to discuss all medications, supplements, and over-the-counter products you're using with your healthcare provider before starting this treatment.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us.

How Does it Work

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This formulation is a combination of five active ingredients: Carbamazepine, Doxepin, Gabapentin, Ketoprofen, and Lidocaine, each playing a unique role in managing various disease states. The formulation is designed to be applied topically, directly to the skin, where it is absorbed into the body to provide targeted treatment.

Carbamazepine is an anticonvulsant and mood stabilizer. It works by reducing the spread of seizure activity in the brain and restoring the normal balance of nerve activity. In this formulation, it can help to manage nerve pain and certain types of mood disorders.

Doxepin is a tricyclic antidepressant that increases the levels of certain natural substances in the body that are needed for mental balance. It is used in this formulation to help manage anxiety and depression, and it can also help to alleviate itching and hives caused by skin conditions.

Gabapentin is an anticonvulsant that affects chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. It is used in this formulation to help manage nerve pain caused by herpes virus or shingles (herpes zoster).

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. In this formulation, it can help to manage pain and inflammation caused by arthritis, menstrual cramps, or other conditions.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. It is used in this formulation to provide temporary relief of pain and discomfort from skin irritations and minor cuts or burns.

The transdermal gel formulation allows for the active ingredients to be absorbed directly through the skin, providing targeted treatment to the area of application. The gel is dispensed through a pump mechanism, which allows for easy and precise application.

This formulation is a powerful tool in managing a variety of disease states, providing relief from symptoms and improving the quality of life for patients. As with any medication, it is important to use this formulation as directed by a healthcare provider, and to communicate any side effects or concerns immediately.

If you have any questions about this formulation, or if you would like more information, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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This formulation, which comprises of Carbamazepine 4%/Doxepin 4%/Gabapentin 4%/Ketoprofen 4%/Lidocaine 1% Transdermal Gel, is primarily used for the management of painful neuropathic conditions, chronic arthritis, and localized myalgia. Its composition allows it to target and ameliorate symptoms like pain, inflammation, and neural neurological dysfunctions by working on multiple pathways in the human body.

Other than its common uses, the combination of ingredients in this formulation might be useful in some other medical conditions. For instance, the Carbamazepine component, which is known for its anticonvulsant properties, may be used in the management of epilepsy. Similarly, Doxepin, being a tricyclic antidepressant, can help in managing certain types of depression and anxiety disorders. Gabapentin is recognized for its efficacy in controlling seizures and relieving neuropathic pain, but it could also be used in treating restless leg syndrome. Ketoprofen acts as a potent nonsteroidal anti-inflammatory drug (NSAID), making the formulation potentially beneficial for reducing fever or minimizing inflammation in conditions such as gout. Lastly, Lidocaine offers local anesthetic properties which can help numb a specific area of the body for minor surgical procedures.

It’s recommended to discuss these potential applications with a healthcare provider before use, as the medication might not be suitable for everyone, and improper dosing could lead to harmful side effects. Not everyone will experience the same benefits or potential risks when using any medication, including this transdermal gel formulation due to individual variability. Therefore, close monitoring by a healthcare professional is necessary. Also, this formulation is designed for external use only and should not be ingested, applied to the eyes, or used internally.

If you have any questions about this formulation or its possible applications, feel free to reach out to us at Bayview Pharmacy. Remember, it's essential to use medications under the direction of a healthcare professional who understands your medical history and current health status.

Frequently Asked Questions

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What is the Carbamazepine 4%/Doxepin 4%/Gabapentin 4%/Ketoprofen 4%/Lidocaine 1% Transdermal Gel?

It is a compounded formulation containing five active ingredients in a gel-like consistency that is designed to be applied directly to the skin using a pump mechanism. The mixture is typically made in a pharmacy and is designed to provide targeted treatment.

What does the percentage in the name mean?

The percentages refer to the concentration of each active ingredient in the formulation. For instance, 'Carbamazepine 4%' refers to the fact that 4% of the formulation consists of Carbamazepine.

How to use the transdermal gel?

This gel is dispensed through a pump mechanism which allows for easy and precise application. Apply it to the affected area as directed by your healthcare provider.

What is a transdermal gel?

A transdermal gel is a semisolid formulation that is designed to transfer the active ingredients within it through the skin and into the bloodstream. This allows for direct, localized treatment or system-wide absorption.

Can everyone use this gel?

As with any medication, its use will depend on an individual's medical history and existing conditions. Always consult with your healthcare professional before beginning any new medication.

Are there any side effects of using this gel?

Yes, potential side effects can range from skin irritation to more serious reactions depending on the specific active ingredients and individual tolerances. Consult your healthcare provider for a comprehensive list of potential side effects.

Can this gel be used with other medications?

Before starting to use this gel, you should consult with your healthcare provider and inform them about any other medications, supplements, or herbal products you are currently taking to avoid possible interactions.

Can the gel be applied anywhere on the body?

Generally, the gel is applied on areas as directed by your healthcare provider. However, it should not be applied on broken skin, near the eyes, mouth, or mucous membranes.

How should the gel be stored?

The gel should be kept in a cool, dry place away from direct light and out of the reach of children. Always refer to the specific storage instructions provided by your pharmacist or healthcare provider.

What should I do if I forget a dose?

If you miss a dose, apply it as soon as you remember. However, if it's close to the time of your next scheduled dose, skip the missed dose and continue as directed. Avoid applying double doses unless instructed by your healthcare provider.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Carbamazepine 4%/Doxepin 4%/Gabapentin 4%/Ketoprofen 4%/Lidocaine 1% Transdermal Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)