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Formulas

Clonidine HCl 0.166%/Diclofenac Sodium 2%/Gabapentin 6%/Lidocaine 2%/Pentoxifylline 5% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Clonidine Hydrochloride
Diclofenac Sodium
Gabapentin
Pentoxifylline Hydrochloride
Lidocaine Hydrochloride

This formulation is a compounded topical gel containing Clonidine HCl 0.166%, Diclofenac Sodium 2%, Gabapentin 6%, Lidocaine 2%, and Pentoxifylline 5%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The combination of these active ingredients is designed to treat a variety of disease states. Clonidine HCl is used for its analgesic properties, Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce pain and inflammation, Gabapentin is used to manage nerve pain, Lidocaine is a local anesthetic that provides numbing effects, and Pentoxifylline is a xanthine derivative that improves blood flow. This formulation is commonly used to manage conditions such as neuropathic pain, inflammation, and circulatory disorders.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Clonidine Hydrochloride
Diclofenac Sodium
Gabapentin
Pentoxifylline Hydrochloride
Lidocaine Hydrochloride
Topical Gel
653f8cf16aa0096209e04384
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This formulation is a compounded topical gel containing Clonidine HCl 0.166%, Diclofenac Sodium 2%, Gabapentin 6%, Lidocaine 2%, and Pentoxifylline 5%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Clonidine HCl is a medication that is primarily used to treat high blood pressure, but in this formulation, it is used for its potential analgesic and anti-inflammatory properties. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and reduce inflammation. Gabapentin is a medication that is primarily used to treat seizures and nerve pain. In this formulation, it is used for its potential analgesic and anti-inflammatory properties. Lidocaine is a local anesthetic that is used to numb the skin and relieve pain. Pentoxifylline is a medication that is used to improve blood flow and reduce inflammation.

This formulation is used to treat a variety of disease states. The combination of these active ingredients can provide relief from pain and inflammation associated with conditions such as arthritis, neuropathic pain, and other musculoskeletal conditions. The gel formulation allows for targeted treatment, which can be beneficial for localized pain and inflammation. The pump mechanism allows for easy and precise application, which can be particularly beneficial for patients who have difficulty applying topical medications.

It is important for patients and prescribers to understand that this is a compounded medication, which means it is made specifically for the patient based on a prescription from a healthcare provider. The strength and combination of the active ingredients can be adjusted based on the patient's specific needs and the disease state being treated. As with any medication, it is important to use this formulation as directed by a healthcare provider and to report any side effects or adverse reactions.

If you have any questions about this formulation or how it can be used to treat specific disease states, please reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to help.

Drug Interactions

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This compounded formulation contains Clonidine HCl, Diclofenac Sodium, Gabapentin, Lidocaine, and Pentoxifylline. Each of these active ingredients can interact with other medications, potentially altering their effects. It's important to inform your healthcare provider about all the medications you're currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements.

Clonidine HCl, a medication primarily used to treat high blood pressure, can interact with beta-blockers, calcium channel blockers, and digitalis. Concurrent use of these medications can lead to a significant drop in blood pressure. Clonidine HCl can also interact with tricyclic antidepressants, potentially reducing its antihypertensive effect.

Diclofenac Sodium, a nonsteroidal anti-inflammatory drug (NSAID), can interact with anticoagulants, antiplatelet drugs, and other NSAIDs, increasing the risk of gastrointestinal bleeding. It can also interact with diuretics and ACE inhibitors, potentially impairing kidney function. Concurrent use with lithium or methotrexate can increase the levels of these drugs in the body, leading to toxicity.

Gabapentin, a medication used to treat nerve pain and seizures, can interact with antacids, reducing its absorption and effectiveness. It's recommended to take gabapentin at least 2 hours after taking an antacid. Gabapentin can also increase the effects of certain central nervous system depressants, including opioids, antihistamines, and alcohol.

Lidocaine, a local anesthetic, can interact with other local anesthetics and antiarrhythmic drugs, potentially leading to additive systemic toxicity. It can also interact with certain antibiotics and antifungal medications, potentially increasing their side effects.

Pentoxifylline, a medication used to improve blood flow, can interact with anticoagulants and antiplatelet drugs, increasing the risk of bleeding. It can also interact with theophylline, potentially increasing the levels of theophylline in the body and leading to toxicity.

This compounded formulation is designed to be applied topically, which can reduce the risk of systemic drug interactions. However, systemic absorption can still occur, especially when applied over large areas of skin or for prolonged periods. Therefore, it's important to use this medication as directed by your healthcare provider.

This formulation is used to treat various disease states. Clonidine HCl can help manage neuropathic pain. Diclofenac Sodium provides anti-inflammatory and analgesic effects. Lidocaine provides local numbing effect, reducing pain and discomfort. Pentoxifylline improves blood flow, aiding in wound healing and reducing inflammation.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us.

How Does it Work

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This formulation combines the therapeutic effects of five active ingredients: Clonidine HCl, Diclofenac Sodium, Gabapentin, Lidocaine, and Pentoxifylline. Each of these ingredients works in a unique way to alleviate pain and inflammation, making this a versatile treatment option for a variety of conditions.

Clonidine HCl is a medication primarily used to treat high blood pressure, but in this formulation, it is used for its pain-relieving properties. It works by stimulating alpha-2 adrenergic receptors in the brain, which helps to decrease nerve signal transmission and thus reduce pain sensation.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. It is commonly used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis.

Gabapentin is a medication used to treat nerve pain. It works by stabilizing electrical activity in the nervous system and reducing the release of neurotransmitters that transmit pain signals from the nerves to the brain. This helps to decrease the perception of pain.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. It is used to reduce pain or discomfort caused by skin irritations such as sunburn, insect bites, poison ivy, poison oak, poison sumac, and minor cuts, scratches, or burns.

Pentoxifylline is a xanthine derivative that improves blood flow and reduces inflammation. It works by increasing the flexibility of red blood cells, which allows them to deliver more oxygen to muscles and other tissues. This can help to alleviate pain and inflammation associated with poor circulation.

The semisolid formulation dispensed through a pump mechanism allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively into the skin for targeted treatment. This formulation is designed to provide relief from pain and inflammation associated with a variety of conditions, including arthritis, nerve pain, skin irritations, and conditions associated with poor circulation.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Frequently Asked Questions

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What is the consistency of this compounded formulation?

The compounded formulation of Clonidine HCl 0.166%/Diclofenac Sodium 2%/Gabapentin 6%/Lidocaine 2%/Pentoxifylline 5% Topical Gel is a semi-solid formulation. It has a gel-like consistency that is easy to apply to the skin.

How is this compounded formulation applied?

The compounded formulation is applied topically. It can be easily and precisely dispensed through a pump mechanism onto the skin.

What is the purpose of using this compounded formulation?

This formulation contains active ingredients that are targeted for treatment or absorption through the skin when applied. The composition of active ingredients is designed for its intended medical use.

Is this formulation safe to use on all skin types?

Generally, Yes. However, if you have a history of skin allergies or sensitive skin, you should consult a health care provider before using any new topical product. This applies to this compounded formulation as well.

Can this formulation be used along with other medications?

Before using this formulation with other medications, it's recommended to consult your healthcare provider. They can advise on the potential interactions and precautions – if any – between this formulation and other medicines you are taking.

How often should I use this compounded formulation?

The frequency of the application should be as recommended by your healthcare provider. It's important to adhere to these directions to achieve the intended therapeutic effect.

How should I store this compounded formulation?

Store this formulation in a cool and dry place, away from direct sunlight. Always replace the cap tightly after use and make sure the pump mechanism is clean.

Can this compounded formulation be used by pregnant or breastfeeding women?

Before using the formulation during pregnancy or while breastfeeding, it's essential to consult a health care provider. They will consider the potential benefits and risks before recommending usage.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up the dose to make up for the missed one.

What happens if I apply too much of this formulation?

Applying more than the recommended amount will not enhance the therapeutic effects. On the contrary, it might increase the risks of side effects. If you've applied too much, rinse the area with water and contact your healthcare provider if any adverse effects are noticed.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Clonidine HCl 0.166%/Diclofenac Sodium 2%/Gabapentin 6%/Lidocaine 2%/Pentoxifylline 5% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily