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Formulas

Cyclobenzaprine HCl 3%/Ketoprofen 15%/Lidocaine 5% Transdermal Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Cyclobenzaprine Hydrochloride
Ketoprofen
Lidocaine Hydrochloride

This formulation is a combination of Cyclobenzaprine HCl 3%, Ketoprofen 15%, and Lidocaine 5% in a transdermal gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is designed to treat a variety of disease states. Cyclobenzaprine HCl is a muscle relaxant used to alleviate muscle spasms, Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation, and Lidocaine is a local anesthetic that numbs the skin and surrounding tissues.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Cyclobenzaprine Hydrochloride
Ketoprofen
Lidocaine Hydrochloride
Topical Gel
653ecc5b0d914f2541500228

Formula Information

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This formulation is a unique combination of Cyclobenzaprine HCl 3%, Ketoprofen 15%, and Lidocaine 5% in a transdermal gel. Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination of ingredients is designed to provide targeted relief from pain and inflammation.

The transdermal gel formulation allows for the active ingredients to be absorbed directly through the skin, providing localized relief to the affected area. The gel is dispensed through a pump mechanism, which allows for easy and precise application. This is particularly beneficial for patients who may have difficulty swallowing pills or who prefer a non-invasive method of medication administration.

This formulation can be used to treat a variety of disease states. Cyclobenzaprine HCl can be used to relieve muscle spasms caused by conditions such as sprains, strains, or other muscle injuries. Ketoprofen can be used to treat pain or inflammation caused by conditions such as arthritis, bursitis, and gout. Lidocaine can be used to relieve pain and discomfort caused by skin irritations, such as minor cuts, burns, and abrasions, as well as to relieve itching and discomfort due to hemorrhoids.

As with any medication, it's important to use this formulation as directed by your healthcare provider. Side effects may include skin irritation at the application site, dizziness, drowsiness, or dry mouth. If any of these side effects persist or worsen, or if you experience any other side effects, contact your healthcare provider immediately.

It's also important to inform your healthcare provider of all other medications you are currently taking, as there may be potential interactions with this formulation. This includes prescription medications, over-the-counter medications, vitamins, and herbal supplements.

If you have any questions about this formulation, or if you would like more information, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Drug Interactions

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This formulation contains three active ingredients: Cyclobenzaprine HCl, Ketoprofen, and Lidocaine. Each of these ingredients can interact with other medications, potentially altering their effects or increasing the risk of adverse reactions.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It can interact with monoamine oxidase inhibitors (MAOIs), increasing the risk of serious side effects such as high fever, severe headache, stiff muscles, and confusion. It can also interact with other central nervous system depressants, including alcohol, antihistamines, sedatives, tranquilizers, and certain analgesics, potentially leading to increased sedation and respiratory depression.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. It can interact with blood thinners, such as warfarin, increasing the risk of bleeding. It can also interact with other NSAIDs, corticosteroids, and alcohol, increasing the risk of gastrointestinal bleeding. Additionally, it can interact with certain blood pressure medications, potentially reducing their effectiveness.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. It can interact with certain heart medications, potentially leading to heart rhythm problems. It can also interact with other local anesthetics and certain seizure medications, potentially increasing the risk of adverse effects.

This formulation is designed to treat a variety of disease states. Cyclobenzaprine HCl can help to relieve muscle spasms associated with painful musculoskeletal conditions. Ketoprofen can help to reduce pain and inflammation associated with conditions such as arthritis, bursitis, and tendonitis. Lidocaine can help to numb the skin and relieve pain associated with conditions such as post-herpetic neuralgia and other nerve-related pain conditions.

It's important to inform your healthcare provider of all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements, to avoid potential drug interactions. If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy.

How Does it Work

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The Cyclobenzaprine HCl 3%/Ketoprofen 15%/Lidocaine 5% Transdermal Gel is a unique formulation that combines the therapeutic benefits of three active ingredients. Each of these ingredients plays a crucial role in managing pain and inflammation.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. When applied topically in a gel form, it can provide targeted relief to the affected area.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. It is used to treat mild to moderate pain, or inflammation caused by conditions such as arthritis. In this formulation, Ketoprofen is absorbed through the skin to provide localized relief from pain and inflammation.

Lidocaine is a local anesthetic that works by causing temporary numbness in the area where it is applied. It achieves this by blocking the nerve signals in your body. In this formulation, Lidocaine provides immediate relief from pain by numbing the affected area.

The gel formulation allows for easy and precise application of these active ingredients directly to the area of pain or inflammation. The transdermal delivery system ensures that the active ingredients are absorbed through the skin and into the affected area, providing targeted relief. The gel-like consistency also ensures that the formulation stays on the skin for a longer period, allowing for sustained release of the active ingredients.

By combining the muscle relaxant properties of Cyclobenzaprine HCl, the anti-inflammatory properties of Ketoprofen, and the anesthetic properties of Lidocaine, this formulation provides comprehensive relief from pain and inflammation.

If you have any questions about this formulation, or if you would like to know more about how it can benefit you, please do not hesitate to reach out to us. Our team of knowledgeable compounding pharmacists at Bayview Pharmacy is always here to help.

Other Uses

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This specialized formulation of Cyclobenzaprine HCl 3%/Ketoprofen 15%/Lidocaine 5% Transdermal Gel, while often used for the treatment of a variety of conditions, can also provide relief in other contexts as well. It has potential applications beyond the primary usage scenarios. Outside of conventional disease states, it can also be used to manage pain arising from sports injuries or sprains and may be recommended for post-surgical discomfort management due to its ability to provide targeted relief.

Ketoprofen, a primary ingredient in this formulation, is a nonsteroidal anti-inflammatory drug (NSAID), and along with Cyclobenzaprine — a muscle relaxant, and Lidocaine — a local anesthetic, the triple combination works synergistically to relieve pain, reduce inflammation, and relaxing underlying muscles and tissues. Thus, this formulation could be beneficial in treating various other conditions involving inflammation or muscle spasms including but not limited to tendonitis, bursitis, or even relieving pain from minor burns or insect bites.

Furthermore, this transdermal gel can also potentially be used for cases where oral medication administration is not suitable or is inconvenient. Due to its transdermal application, it provides a localized effect and hence, can minimize systemic side effects usually experienced with oral medications. However, as the use of this product extends beyond conventional categories, it is important to consult with a healthcare provider before using the gel for off-label purposes. It’s crucial that users understand the specific characteristics and interactions of the ingredients in order to ensure safe and appropriate use.

This information is provided as a guideline and does not substitute professional medical advice. Unintended side effects may occur with any medication, so it is important to report any adverse events to your healthcare provider immediately. If you have any questions about this formulation or its other potential applications, don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Frequently Asked Questions

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What is Cyclobenzaprine HCl 3%/Ketoprofen 15%/Lidocaine 5% Transdermal Gel?

This is a semisolid formulation of Cyclobenzaprine, Ketoprofen, and Lidocaine. It is dispensed through a pump mechanism, making it easy and precise to apply on the skin for targeted treatment or absorption. The active ingredients are presented in a gel-like consistency.

How does the Cyclobenzaprine HCl 3%/Ketoprofen 15%/Lidocaine 5% Transdermal Gel work?

The gel works by delivering active ingredients directly to the area of pain or discomfort after being applied to the skin. The ingredients, once absorbed, act to provide relief from various forms of pain and inflammation.

What specifically do each of the active ingredients in this formulation do?

Cyclobenzaprine acts as a muscle relaxant, Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce swelling and pain, and Lidocaine is a local anesthetic that numbs the specific area of application.

How should I use this transdermal gel?

You should apply the gel directly to the skin in the area of pain or discomfort as directed by your healthcare provider. The gel is dispensed through a pump for precise and convenient application.

Who can use this transdermal gel?

This formulation is often used by adults or as directed by a healthcare provider. However, it should not be used by individuals who may be sensitive or allergic to any of the active ingredients.

Can I use this transdermal gel with other medications?

Always consult with your healthcare provider prior to combining this gel with other medications, as there may be interactions.

What are the potential side effects of this transdermal gel?

While generally well-tolerated, potential side effects may include skin irritation at the site of application or systemic effects related to the individual active ingredients. If you experience any adverse reactions, consult with your healthcare provider immediately.

What should I do if I miss a dose of this transdermal gel?

If you miss a dose, apply it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

How should I store this transdermal gel?

The gel should be stored in a cool, dry place, away from heat and direct light. Make sure to keep the container tightly closed when not in use.

Are there any safety precautions I should be aware of when using this gel?

Do not apply the gel on broken or irritated skin, mucous membranes, or in the eyes. If the gel does come in contact with these areas, rinse with cool water. Avoid sun exposure or use sunscreen while using this medication as it could cause photosensitivity.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Cyclobenzaprine HCl 3%/Ketoprofen 15%/Lidocaine 5% Transdermal Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)