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Diphenhydramine HCl 1%/Naltrexone HCl 0.5% Topical Cream

FDA-approved generic
Dose form
Topical Cream
Active ingredients
Diphenhydramine Hydrochloride
Naltrexone Hydrochloride

Bayview Pharmacy's Diphenhydramine HCl 1%/Naltrexone HCl 0.5% Topical Cream is a specially compounded medication designed to treat a variety of skin conditions including Atopic Dermatitis, Psoriasis, Pruritus, Acne, and Eczema. This semisolid preparation is dispensed via a pump mechanism for easy and controlled application, ensuring localized treatment and effective absorption of active ingredients.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Diphenhydramine Hydrochloride
Naltrexone Hydrochloride
Topical Cream
6427079ea6432414e95189e1
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Formula Information

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Bayview Pharmacy is pleased to present a specialized topical cream formulation of Diphenhydramine HCl 1%/Naltrexone HCl 0.5%. This unique combination of active ingredients is designed to address a range of conditions, including allergic reactions, itching, and pain.

Diphenhydramine HCl is an antihistamine that functions to mitigate the effects of histamine, a substance released by the body during an allergic reaction. On the other hand, Naltrexone HCl is an opioid antagonist that works to alleviate pain and inflammation.

This compounded formulation is a potent treatment for a variety of conditions, including allergic reactions, itching, and pain. The cream is dispensed in a pump mechanism, designed for convenient and controlled application on the skin. This allows for localized treatment or absorption of the active ingredients, making it an easy-to-use option for regular symptom relief.

If you have any inquiries about this formulation or how it can be utilized to manage your condition, please do not hesitate to contact us at Bayview Pharmacy. We are committed to assisting you in finding the most suitable treatment option for your specific needs.

Drug Interactions

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This Diphenhydramine HCl 1%/Naltrexone HCl 0.5% Topical Cream is a compounded formulation designed for localized treatment of various skin conditions and opioid dependence. The cream is a semisolid preparation dispensed in a pump mechanism, which allows for convenient and controlled application on the skin.

It can help reduce inflammation and itching associated with these conditions. The inclusion of naltrexone, an opioid antagonist, also makes this formulation useful in the treatment of opioid dependence. However, it should not be used as a standalone treatment for opioid dependence and should be used in conjunction with counseling and behavioral therapy.

Patients should be aware that this formulation may cause skin irritation, redness, or burning at the site of application. If these side effects occur, discontinue use and contact your healthcare provider. This formulation may also interact with other medications, including anticholinergics, antihistamines, and opioids. Therefore, it is crucial to inform your healthcare provider of all medications you are currently taking before using this formulation.

Prescribers should note that this formulation should not be used in patients with a known hypersensitivity to any of the ingredients. It should also not be used in patients with a history of opioid abuse or dependence. If you have any questions about this formulation or its use, please consult with your healthcare provider.

How Does it Work

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Diphenhydramine HCl 1%/Naltrexone HCl 0.5% Topical Cream is a compounded formulation designed to treat a variety of skin conditions. This semisolid preparation is dispensed in a pump mechanism for convenient and controlled application on the skin. The cream is formulated with two active ingredients, diphenhydramine hydrochloride and naltrexone hydrochloride, which work synergistically to alleviate inflammation and itching.

Diphenhydramine hydrochloride is an antihistamine that functions by blocking the action of histamine, a substance released by the body during an allergic reaction. On the other hand, naltrexone hydrochloride is an opioid antagonist that works by blocking the action of opioid receptors in the body, thereby reducing inflammation and itching.

When using Diphenhydramine HCl 1%/Naltrexone HCl 0.5% Topical Cream, it is crucial to adhere to the instructions provided by your healthcare provider. The medication should be applied to the affected skin area as directed. Avoid contact with the eyes, nose, and mouth. If contact occurs, rinse the area thoroughly with water. It is also important to avoid ingesting the medication.

Like all medications, Diphenhydramine HCl 1%/Naltrexone HCl 0.5% Topical Cream may cause side effects such as skin irritation, burning, stinging, redness, or dryness. If these or any other side effects occur, it is important to contact your healthcare provider. Always inform your healthcare provider of any other medications, vitamins, or herbal supplements you are taking to avoid potential interactions.

If you have any questions or concerns about Diphenhydramine HCl 1%/Naltrexone HCl 0.5% Topical Cream, do not hesitate to reach out to your healthcare provider or pharmacist. They are equipped with the knowledge and expertise to assist you with your medication needs.

Frequently Asked Questions

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What is Diphenhydramine HCl 1%/Naltrexone HCl 0.5% Topical Cream?

This is a compounded formulation of two active ingredients, Diphenhydramine HCl and Naltrexone HCl, in a semisolid preparation. It is designed for topical application on the skin for localized treatment.

How is this cream dispensed?

The cream is dispensed in a pump mechanism, which allows for convenient and controlled application on the skin.

What is the purpose of the Diphenhydramine HCl in this formulation?

Diphenhydramine HCl is an antihistamine that is used to relieve symptoms of allergy, hay fever, and the common cold. These symptoms include rash, itching, watery eyes, itchy eyes/nose/throat, cough, runny nose, and sneezing.

What is the purpose of the Naltrexone HCl in this formulation?

Naltrexone HCl is used to prevent relapse in people who became dependent on opioid medicine and then stopped using it. It can help keep you from feeling a "need" to use the opioid.

How should I apply this cream?

Apply a thin layer of the cream to the affected area as directed by your healthcare provider. The pump mechanism allows for controlled application.

Can I use this cream on any part of my body?

This cream is designed for localized treatment, so it should only be applied to the area of skin directed by your healthcare provider. Avoid contact with eyes, mouth, and other mucous membranes.

What should I do if I experience any side effects?

If you experience any side effects such as redness, irritation, or worsening of your symptoms, stop using the cream and contact your healthcare provider immediately.

Can I use this cream if I am pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should consult your healthcare provider before using this cream. The active ingredients may be absorbed through the skin and could potentially affect the baby.

Can I use this cream with other medications?

Before using this cream, inform your healthcare provider about any other medications you are currently taking, including over-the-counter drugs and supplements. Some medications may interact with the active ingredients in this cream.

How should I store this cream?

Store this cream at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children and pets.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Diphenhydramine HCl 1%/Naltrexone HCl 0.5% Topical Cream
Topical Cream
30 g
controlled

Apply topically to affected area(s)

Twice daily