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Ketamine HCl 10%/Amitriptyline HCl 5% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Ketamine Hydrochloride
Amitriptyline Hydrochloride

Bayview Pharmacy's Ketamine HCl 10%/Amitriptyline HCl 5% Topical Gel is a semisolid formulation dispensed through a pump mechanism. This design allows for easy and precise application on the skin, facilitating targeted treatment or absorption of active ingredients. The gel-like consistency of the medication is specifically compounded to treat conditions such as neuropathic pain, fibromyalgia, migraine, complex regional pain syndrome, and trigeminal neuralgia.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Ketamine Hydrochloride
Amitriptyline Hydrochloride
Topical Gel
6427079ea64324cc57518cbd
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Formula Information

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Bayview Pharmacy is pleased to present a specially compounded topical gel formulation of Ketamine HCl 10%/Amitriptyline HCl 5%. This unique formulation is specifically designed to provide targeted relief from a range of chronic pain conditions, including neuropathic pain, fibromyalgia, migraines, and complex regional pain syndrome.

Ketamine, a well-established anesthetic agent, has been utilized in clinical settings for many years. Amitriptyline, a tricyclic antidepressant, has demonstrated efficacy in treating neuropathic pain, fibromyalgia, and migraines.

The innovative combination of these two medications in a topical gel formulation allows for the direct delivery of both medications to the pain site. This targeted approach to pain relief is facilitated by the gel's semisolid formulation, which is dispensed through a pump mechanism for easy and precise application. The gel-like consistency ensures optimal absorption of the active ingredients.

Furthermore, the topical gel formulation significantly reduces the risk of systemic side effects often associated with oral medications. This makes it an excellent treatment option for patients suffering from chronic pain, neuropathic pain, fibromyalgia, migraines, and complex regional pain syndrome.

If you have any questions or require further information about this unique compounded formulation, please do not hesitate to contact us at Bayview Pharmacy.

Drug Interactions

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This compounded formulation of Ketamine HCl 10%/Amitriptyline HCl 5% Topical Gel is a semisolid preparation that is dispensed through a pump mechanism. This design allows for easy and precise application on the skin, targeting the treatment area directly and facilitating the absorption of the active ingredients in a gel-like consistency. This formulation has been utilized in the management of various chronic pain conditions, including neuropathic pain, fibromyalgia, migraines, and complex regional pain syndrome.

The therapeutic action of this combination is believed to be due to the modulation of neurotransmitters such as serotonin and norepinephrine, which play a crucial role in the transmission of pain signals.

It is crucial to note that this formulation should not be used by patients with a history of glaucoma, as it may lead to an increase in intraocular pressure. Additionally, patients should be closely monitored for signs of serotonin syndrome, as the combination of ketamine and amitriptyline may heighten the risk of this condition. For any queries or concerns regarding this formulation or its use in treating chronic pain conditions, please consult with a healthcare professional.

How Does it Work

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Ketamine HCl 10%/Amitriptyline HCl 5% Topical Gel is a compounded formulation specifically designed to address chronic pain, neuropathic pain, fibromyalgia, migraines, and complex regional pain syndrome. This unique combination of active ingredients works synergistically to block pain signals to the brain, reduce inflammation, and provide a calming effect.

The gel is dispensed through a pump mechanism, which allows for easy and precise application directly to the affected area. This targeted treatment ensures that the active ingredients are absorbed exactly where they are needed, maximizing their effectiveness. The gel-like consistency ensures that the medication stays in place, providing continuous relief.

It can be applied up to four times a day, depending on the severity of the pain and the recommendation of your healthcare provider. However, it is crucial to avoid applying this medication on open wounds or broken skin to prevent any potential complications.

These may include skin irritation, redness, or a burning sensation. If you experience any of these side effects, discontinue use and contact your healthcare provider immediately.

As with any medication, it is essential to follow the instructions provided by your healthcare provider. If you have any questions or concerns about Ketamine HCl 10%/Amitriptyline HCl 5% Topical Gel, or if you need further information on how it works, do not hesitate to reach out.

Other Uses

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This compounded formulation of Ketamine HCl 10%/Amitriptyline HCl 5% Topical Gel is a semisolid preparation designed for easy and precise application on the skin. The pump mechanism allows for targeted treatment, ensuring the active ingredients are absorbed effectively in a gel-like consistency. This formulation is primarily used for the management of neuropathic pain, fibromyalgia, migraine, complex regional pain syndrome, and trigeminal neuralgia.

It is crucial to understand that this formulation is strictly for topical use and should not be ingested. It is not intended for use in treating other conditions. Additionally, it should not be used concurrently with other topical medications, as this could potentially increase the risk of adverse effects.

Patients should be aware that this formulation may cause skin irritation and should be used with caution. If any adverse effects occur, such as redness, itching, or swelling, it is recommended to discontinue use immediately and consult with a healthcare provider. This formulation should be used with caution in patients with a history of skin allergies or sensitivities.

Prescribers should be aware of the patient's medical history and potential skin sensitivities before recommending this formulation. If there are any questions or concerns about this formulation, it is advised to consult with a healthcare provider for further information and guidance.

Frequently Asked Questions

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What is the Ketamine HCl 10%/Amitriptyline HCl 5% Topical Gel?

This is a semisolid formulation that contains 10% Ketamine HCl and 5% Amitriptyline HCl. It is dispensed through a pump mechanism for easy and precise application on the skin.

What is the consistency of this topical gel?

The gel has a semisolid, gel-like consistency that allows for targeted treatment or absorption of the active ingredients.

How is the Ketamine HCl 10%/Amitriptyline HCl 5% Topical Gel applied?

The gel is applied topically on the skin. It is dispensed through a pump mechanism, which facilitates easy and precise application.

What is the purpose of the pump mechanism?

The pump mechanism is designed to facilitate easy and precise application of the gel on the skin. It ensures that the right amount of gel is dispensed each time.

Can this gel be used for any skin condition?

Not necessarily. The use of this gel should be as per the prescription of a healthcare provider. It is primarily used for targeted treatment or absorption of its active ingredients.

What are the active ingredients in this gel?

The active ingredients in this gel are Ketamine HCl and Amitriptyline HCl.

What is the role of Ketamine HCl in this gel?

Ketamine HCl is a potent analgesic that provides relief from pain. It is one of the active ingredients in this gel.

What is the role of Amitriptyline HCl in this gel?

Amitriptyline HCl is an antidepressant that can also help relieve certain types of pain. It is one of the active ingredients in this gel.

Can this gel be used on all skin types?

Generally, this gel can be used on all skin types. However, if you have sensitive skin or any specific skin condition, it is advisable to consult your healthcare provider before using this gel.

What should I do if I experience any side effects?

If you experience any side effects after using this gel, you should immediately stop using it and consult your healthcare provider.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Ketamine HCl 10%/Amitriptyline HCl 5% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily as needed