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Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Ketoprofen
Lidocaine Hydrochloride

The Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel is a specialized semisolid formulation designed for targeted pain relief. This gel is dispensed through a pump mechanism, which allows for easy and precise application directly onto the skin. The consistency of the gel ensures that the active ingredients, ketoprofen and lidocaine, are absorbed efficiently at the site of application.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that provides relief by reducing inflammation and pain in the affected area. Lidocaine HCl is a local anesthetic that numbs the skin, offering immediate relief from pain. It is commonly used for conditions such as arthritis, tendonitis, bursitis, and other similar disease states where inflammation and pain are present.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Ketoprofen
Lidocaine Hydrochloride
Topical Gel
65aedb59a3ceab5d48876d09
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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The Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel is a specialized medication designed for topical application to provide targeted relief from pain and inflammation. This semisolid formulation is dispensed through a pump mechanism, which ensures that patients can apply a consistent and precise dose of the medication to the affected area. The gel base allows for the active ingredients to be absorbed through the skin, offering a localized effect while minimizing systemic exposure and potential side effects.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzymes responsible for producing prostaglandins, which are compounds that contribute to inflammation, pain, and fever. By reducing the levels of prostaglandins, ketoprofen effectively alleviates inflammation and pain. This makes the gel particularly useful for treating conditions such as arthritis, muscle sprains, strains, and other musculoskeletal injuries where inflammation is a primary concern.

Lidocaine HCl, on the other hand, is a local anesthetic that provides temporary relief from pain by blocking the transmission of pain signals along the nerves. When combined with ketoprofen, lidocaine enhances the analgesic effects of the formulation. This combination is beneficial for patients who require both the anti-inflammatory properties of an NSAID and the rapid pain relief provided by a local anesthetic.

The transdermal gel is designed to be applied to the skin over the affected area, allowing for direct delivery of the active ingredients to the site of pain and inflammation. The pump dispenser aids in applying the medication cleanly and conveniently, reducing the risk of contamination and ensuring that the correct dosage is administered each time. Patients should follow the prescribed dosing instructions and apply the gel as directed by their healthcare provider.

It is important for patients and prescribers to be aware of potential contraindications, such as hypersensitivity to ketoprofen, lidocaine, or other components of the gel, as well as the possibility of systemic absorption leading to adverse effects in certain individuals. Additionally, the use of this medication should be monitored in patients with a history of gastrointestinal ulcers or bleeding, renal impairment, or those taking anticoagulants or other medications that may interact with NSAIDs.

For further information, guidance on prescribing, or to address any questions regarding the Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is dedicated to providing comprehensive support to ensure the safe and appropriate use of this medication for the benefit of our patients.

Drug Interactions

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The combination of Ketoprofen 15% and Lidocaine HCl 2% in a transdermal gel is designed to provide localized relief from pain and inflammation. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. Lidocaine is a local anesthetic that provides temporary relief of pain by blocking nerve signals in the body.

However, it is important to consider potential drug interactions when using this formulation. Ketoprofen, being an NSAID, can interact with various medications. For instance, concurrent use with other NSAIDs, including over-the-counter aspirin, ibuprofen, and naproxen, can increase the risk of gastrointestinal bleeding or ulcers. Combining ketoprofen with anticoagulants (such as warfarin) or antiplatelet agents (like clopidogrel) can also enhance the risk of bleeding. Patients should be cautious when using ketoprofen with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs), as these can also increase bleeding risk.

Lidocaine, on the other hand, may interact with certain medications that affect cardiac function due to its local anesthetic properties. Caution is advised when using this medication with antiarrhythmic drugs (such as tocainide or mexiletine), as there may be an additive effect on cardiac conduction. Patients taking other local anesthetics or medications that can increase blood levels of lidocaine, such as cimetidine or beta-blockers, should also be monitored closely for signs of toxicity.

It is also important to note that the application of the transdermal gel should be limited to intact skin to avoid systemic absorption that could potentially lead to higher plasma levels of the active ingredients, thereby increasing the risk of systemic side effects and interactions. Patients should avoid using heating pads, electric blankets, heat lamps, saunas, hot tubs, heated water beds, or other heat sources on the treated area as they can increase the absorption of the active ingredients, potentially leading to increased side effects.

Patients with renal or hepatic impairment should use this formulation with caution, as these conditions can affect the metabolism and excretion of ketoprofen and lidocaine, potentially leading to increased systemic exposure and risk of adverse effects. Additionally, patients with a history of allergic reactions to NSAIDs or local anesthetics should avoid using this product.

As with any medication, it is essential to inform your healthcare provider of all the medications, supplements, and herbal products you are currently taking to avoid potential interactions. If you have any questions or concerns about using this transdermal gel formulation, please reach out to us at Bayview Pharmacy for personalized advice and support.

How Does it Work

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The Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel is a specialized medication designed for topical application to provide localized relief from pain and inflammation. This semisolid formulation is dispensed through a pump mechanism, which ensures that patients can apply a consistent and precise dose of the medication to the affected area. The gel base allows for the active ingredients to be delivered directly to the site of pain or inflammation, offering targeted treatment without the systemic side effects often associated with oral medications.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the synthesis of prostaglandins. Prostaglandins are chemical messengers that play a key role in the inflammation process. By reducing their production, ketoprofen effectively decreases inflammation and pain in the tissues where the gel is applied. This makes it particularly useful for treating conditions such as arthritis, strains, sprains, and other musculoskeletal injuries.

Lidocaine HCl is an amide-type local anesthetic that provides rapid numbing of the skin and surrounding tissues. It achieves this by blocking the sodium channels in the neuronal cell membranes, which are necessary for the initiation and conduction of nerve impulses. When applied topically, lidocaine can reduce pain by preventing the nerves in the affected area from sending pain signals to the brain. This can be especially beneficial for patients experiencing sharp, shooting, or burning types of pain.

The combination of ketoprofen and lidocaine in a transdermal gel allows for the synergistic effects of both an anti-inflammatory and an analgesic. The transdermal delivery system also offers the advantage of bypassing the gastrointestinal tract, minimizing the risk of gastrointestinal irritation or other systemic side effects associated with oral NSAIDs.

Patients and prescribers should note that this formulation is intended for external use only and should be applied to intact skin. It is important to follow the dosing instructions provided by the healthcare provider or pharmacist to ensure safe and appropriate use of the medication. The gel should be applied to the affected area and gently massaged until absorbed, usually not exceeding the recommended frequency of application.

For those interested in using the Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel, or if you have any questions regarding this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to effectively manage your condition.

Frequently Asked Questions

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What is Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel used for?

Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel is used for the relief of pain and inflammation in a localized area. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and swelling, while Lidocaine is a topical anesthetic that provides numbing to reduce the sensation of pain. This combination is often used for conditions such as arthritis, muscle pain, or other types of acute pain.

How do I use the gel effectively?

To use this gel effectively, apply a small amount to the affected area as directed by your healthcare provider. The pump mechanism allows for precise dosing. Rub the gel gently into the skin for full absorption. Do not cover with a bandage or heating pad unless advised by a medical professional.

How often can I apply the gel?

The frequency of application depends on your healthcare provider's recommendation, typically it might be applied 2-4 times a day. Do not exceed the prescribed amount or frequency, as this could increase the risk of side effects.

Can I use this gel if I’m pregnant or breastfeeding?

If you are pregnant or breastfeeding, you should discuss the use of Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel with your healthcare provider. They will determine if the potential benefits outweigh the risks to you and your baby.

Are there side effects associated with Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel?

As with all medications, there may be side effects. Common side effects can include skin irritation at the application site. More serious side effects, such as allergic reactions, are less common. If you experience any severe side effects or signs of an allergic reaction, seek medical attention immediately.

Can I apply the gel on broken or damaged skin?

No, do not apply Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel on wounds, cuts, or irritated skin. Use the medication only on intact skin and as directed by your healthcare provider.

How should I store the gel?

Store the gel at room temperature away from direct sunlight and heat. Do not freeze. Keep the cap on when not in use to prevent the product from drying out, and keep out of reach of children and pets.

What should I do if I miss a dose?

If you miss a dose of the gel, apply it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose and proceed with your regular dosing schedule. Do not apply extra gel to make up for the missed dose.

Can I use other topical products along with this gel?

You should consult your healthcare provider before using other topical products in conjunction with Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel. They may advise against it or monitor your treatment more closely.

Will the gel stain my clothes?

The gel should be fully absorbed into the skin before putting on clothes. However, as with many gel products, there is a potential to stain clothing if the product has not completely dried or if it is applied excessively. To avoid staining, allow the gel to dry completely before dressing.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Ketoprofen 15%/Lidocaine HCl 2% Transdermal Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily