Check out our most popular compounded medications! Get Started
Dashboard
Formulas

Spironolactone 5%/Niacinamide 2.5%/Clindamycin 1% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Spironolactone
Niacinamide
Clindamycin Hydrochloride

Bayview Pharmacy's Spironolactone 5%/Niacinamide 2.5%/Clindamycin 1% Topical Gel is a specially compounded medication. This semisolid formulation is dispensed through a pump mechanism, ensuring easy and precise application on the skin. It is designed for targeted treatment or absorption of active ingredients in a gel-like consistency. It is used to treat various skin conditions including Acne Vulgaris, Rosacea, Seborrheic Dermatitis, Perioral Dermatitis, and Folliculitis.

View more
For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Get started as a patient
Get Started
This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
Check if we ship to your state
No prescription yet?

Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Spironolactone
Niacinamide
Clindamycin Hydrochloride
Topical Gel
6427079ea643240f155191e8
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

Check your state

Available in

Tap a state to check it.

Our current service area

Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

Select a state on the map or use the checker.

Formula Information

A small arrow pointing down

Bayview Pharmacy's Spironolactone 5%/Niacinamide 2.5%/Clindamycin 1% Topical Gel is a specially compounded formulation designed to treat a range of skin conditions such as Acne Vulgaris, Rosacea, Seborrheic Dermatitis, Hidradenitis Suppurativa, and Perioral Dermatitis. This unique blend of active ingredients offers a multi-faceted approach to skin care treatment.

Spironolactone, an anti-androgen, works to reduce sebum production and inflammation, two key factors in many skin conditions. Niacinamide is included for its ability to alleviate redness and irritation, further enhancing the soothing properties of the formulation. Clindamycin, an antibiotic, is added to the mix to combat the bacteria that often contribute to these skin conditions. Together, these ingredients synergistically work to reduce inflammation, control sebum production, and combat bacteria, providing a comprehensive treatment strategy.

This semisolid formulation is dispensed through a pump mechanism, facilitating easy and precise application on the skin. The gel-like consistency allows for targeted treatment and efficient absorption of the active ingredients, ensuring optimal effectiveness.

While this formulation is generally safe and well-tolerated, it may cause skin irritation in some individuals. Patients are advised to use this product as directed and to contact their healthcare provider if they experience any adverse effects. It is important to remember that individual responses to medications can vary, and what works best for one person may not work as well for another.

If you have any questions about this Spironolactone 5%/Niacinamide 2.5%/Clindamycin 1% Topical Gel or how it can be used to treat your specific skin condition, please do not hesitate to contact us at Bayview Pharmacy. Our team of compounding pharmacists is always ready to assist and provide the information you need to make informed decisions about your health.

Drug Interactions

A small arrow pointing down

This Spironolactone 5%/Niacinamide 2.5%/Clindamycin 1% topical gel is a semisolid formulation designed for easy and precise application on the skin. It is dispensed through a pump mechanism, ensuring targeted treatment or absorption of active ingredients in a gel-like consistency. This formulation is indicated for the treatment of various skin conditions including Acne Vulgaris, Rosacea, Seborrheic Dermatitis, Hidradenitis Suppurativa, and Perioral Dermatitis.

Spironolactone, an anti-androgen, is included in the formulation to help reduce sebum production and inflammation. Niacinamide is added to help reduce inflammation and redness. Clindamycin, an antibiotic, is incorporated to help reduce the number of Propionibacterium acnes, a bacteria associated with acne.

For Acne Vulgaris, this formulation can be used as a monotherapy or in combination with other topical or systemic treatments. However, it should not be used in combination with other topical antibiotics to avoid antibiotic resistance.

Similarly, for Rosacea, Seborrheic Dermatitis, Hidradenitis Suppurativa, and Perioral Dermatitis, this formulation can be used as a monotherapy or in combination with other topical treatments. Again, it should not be used in combination with other topical antibiotics to prevent antibiotic resistance.

If you have any questions about this formulation or its use in treating any of the above-mentioned disease states, please reach out for further information. It is important to use this formulation as directed by a healthcare professional to ensure its effectiveness and safety.

How Does it Work

A small arrow pointing down

This compounded formulation of Spironolactone 5%/Niacinamide 2.5%/Clindamycin 1% Topical Gel is a semisolid preparation designed for easy and precise application on the skin. It is dispensed through a pump mechanism, ensuring targeted treatment or absorption of the active ingredients in a gel-like consistency.

The formulation combines three active ingredients: Spironolactone, Niacinamide, and Clindamycin. Spironolactone, an anti-androgen, works by reducing the production of sebum, a primary cause of acne, and by decreasing inflammation and redness associated with acne. Niacinamide, a form of vitamin B3, also helps to reduce inflammation and redness, and contributes to the reduction of sebum production. Additionally, it aids in diminishing the appearance of wrinkles and fine lines. Clindamycin, an antibiotic, targets and reduces the bacteria that can cause acne.

This topical gel is used to treat a variety of skin conditions, including acne vulgaris, rosacea, seborrheic dermatitis, hidradenitis suppurativa, and perioral dermatitis. It is applied to the affected area once or twice daily, as directed. Care should be taken to avoid contact with the eyes, nose, and mouth. If irritation occurs, discontinue use and consult your healthcare provider.

If you have any questions about this formulation or its application, please do not hesitate to reach out for further information.

Other Uses

A small arrow pointing down

This compounded formulation of Spironolactone 5%/Niacinamide 2.5%/Clindamycin 1% Topical Gel is a versatile treatment option for a wide range of skin conditions. Beyond these conditions, it has also been utilized to address hyperpigmentation, melasma, and post-inflammatory erythema, contributing to a more even skin tone and improved complexion.

Notably, this formulation has demonstrated efficacy in reducing the appearance of wrinkles and fine lines, enhancing skin texture, and diminishing acne scars and other skin discolorations. This makes it a valuable addition to anti-aging and skin rejuvenation routines. Furthermore, it is suitable for individuals with sensitive skin, as it contains ingredients known to alleviate inflammation and irritation, promoting healthier and more comfortable skin.

While this formulation has a broad range of applications, it is important to consult with a healthcare professional or dermatologist to determine if it is the right treatment for your specific skin condition or concern. Always follow the recommended usage instructions to ensure optimal results and to avoid potential side effects.

Frequently Asked Questions

A small arrow pointing down

What is Spironolactone 5%/Niacinamide 2.5%/Clindamycin 1% Topical Gel?

This is a compounded formulation of three active ingredients: Spironolactone, Niacinamide, and Clindamycin. It is a semisolid formulation that is dispensed through a pump mechanism for easy and precise application on the skin.

What is the purpose of the pump mechanism in this formulation?

The pump mechanism facilitates easy and precise application of the gel on the skin.

What is the consistency of this topical gel?

The Spironolactone 5%/Niacinamide 2.5%/Clindamycin 1% Topical Gel has a gel-like consistency. This makes it easy to apply and allows for targeted treatment or absorption of the active ingredients.

How should I apply this topical gel?

You should apply this gel to the affected area as directed by your healthcare provider. The pump mechanism allows for easy and precise application.

What are the active ingredients in this formulation?

The active ingredients in this formulation are Spironolactone (5%), Niacinamide (2.5%), and Clindamycin (1%).

What is the role of each active ingredient in this formulation?

Spironolactone is a medication that is often used to treat fluid build-up due to heart failure, liver scarring, or kidney disease. Niacinamide is a form of vitamin B3 that has anti-inflammatory properties, and Clindamycin is an antibiotic that fights bacteria in the body.

Can I use this topical gel for any skin condition?

This topical gel is intended for specific skin conditions as prescribed by your healthcare provider. It is not meant for use on all skin conditions. Always consult your healthcare provider before using any new medication.

Are there any side effects associated with this topical gel?

As with any medication, there may be potential side effects. These can vary from person to person. If you experience any unusual symptoms or reactions after using the gel, contact your healthcare provider immediately.

How should I store this topical gel?

Store this topical gel at room temperature, away from heat and direct light. Do not freeze. Keep out of the reach of children and pets.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Spironolactone 5%/Niacinamide 2.5%/Clindamycin 1% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Apply topically to affected area(s) 2 to 3 times a day or as directed by a doctor.
Three times daily