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Formulas

Amitriptyline HCl 2%/Baclofen 2%/Gabapentin 5%/Ketoprofen 20%/Prilocaine 2% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Amitriptyline Hydrochloride
Gabapentin
Ketoprofen
Prilocaine Hydrochloride
Baclofen

This formulation is a compounded topical gel containing Amitriptyline HCl 2%, Baclofen 2%, Gabapentin 5%, Ketoprofen 20%, and Prilocaine 2%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency aids in the targeted treatment or absorption of the active ingredients.

The combination of these active ingredients is designed to manage various disease states. Amitriptyline HCl is a tricyclic antidepressant used for its analgesic properties, Baclofen is a muscle relaxant and antispasmodic agent, Gabapentin is used for neuropathic pain, Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) for pain and inflammation, and Prilocaine is a local anesthetic. This formulation is commonly used in the management of conditions such as neuropathic pain, fibromyalgia, and musculoskeletal pain.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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Requires a prescription from your own provider. Bayview is a pharmacy and does not prescribe.
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Amitriptyline Hydrochloride
Gabapentin
Ketoprofen
Prilocaine Hydrochloride
Baclofen
Topical Gel
65305bc97509496e6a5b300a
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This formulation is a compounded topical gel containing Amitriptyline HCl 2%, Baclofen 2%, Gabapentin 5%, Ketoprofen 20%, and Prilocaine 2%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

Amitriptyline HCl is a tricyclic antidepressant that is used in this formulation for its analgesic properties. It can help to relieve chronic pain, especially neuropathic pain. Baclofen is a muscle relaxant and antispastic agent that can help to relieve muscle spasms, tightness, and pain. Gabapentin is an anticonvulsant and nerve pain medication that can help to relieve nerve pain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that can help to reduce inflammation and pain. Prilocaine is a local anesthetic that can help to numb the skin and relieve pain.

This formulation can be used to treat various disease states that involve pain and inflammation. It can be particularly useful for conditions such as neuropathic pain, fibromyalgia, musculoskeletal pain, and certain types of arthritis. The combination of these active ingredients can provide a multi-modal approach to pain management, targeting different aspects of pain and inflammation for a more comprehensive treatment.

For patients, it is important to apply this medication as directed by your healthcare provider. Avoid contact with eyes, nose, mouth, and other sensitive areas. If irritation or adverse reactions occur, discontinue use and consult your healthcare provider. For prescribers, it is important to consider the individual patient's condition, pain level, and potential for drug interactions when prescribing this formulation.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to assist you.

Drug Interactions

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This compounded formulation contains Amitriptyline HCl, Baclofen, Gabapentin, Ketoprofen, and Prilocaine. Each of these active ingredients has its own mechanism of action and potential for drug interactions. It's important to note that this formulation is intended for topical use only and should not be ingested or applied to open wounds or mucous membranes.

Amitriptyline HCl is a tricyclic antidepressant that can interact with MAO inhibitors, SSRIs, anticholinergic drugs, and certain heart medications. It can also increase the effects of alcohol and other CNS depressants. Baclofen is a muscle relaxant and antispastic agent that can interact with other CNS depressants, including alcohol, antihistamines, sedatives, and opioids.

Gabapentin, an anticonvulsant and nerve pain medication, can interact with antacids containing magnesium or aluminum, as well as certain drugs for stomach acid. It can also increase the effects of CNS depressants. Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), can interact with blood thinners, other NSAIDs, corticosteroids, and certain high blood pressure and heart medications. It can also increase the risk of stomach bleeding when combined with alcohol or corticosteroids.

Prilocaine is a local anesthetic that can interact with certain heart medications and other local anesthetics. It can also increase the effects of CNS depressants. It's important to note that the risk of interactions may be lower with topical use compared to oral or systemic use, but it's still important to inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs and supplements.

This formulation is commonly used to treat various disease states such as neuropathic pain, fibromyalgia, and certain types of arthritis. Amitriptyline HCl, Baclofen, and Gabapentin work by reducing nerve impulses, which can help to alleviate pain. Ketoprofen reduces inflammation and pain in the body, while Prilocaine works by numbing the skin and blocking pain signals.

As with any medication, it's important to use this formulation as directed by your healthcare provider. Avoid applying it to broken or irritated skin, and wash your hands thoroughly after application. If you experience any unusual symptoms or side effects, contact your healthcare provider immediately.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need.

How Does it Work

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This formulation is a combination of five active ingredients: Amitriptyline HCl, Baclofen, Gabapentin, Ketoprofen, and Prilocaine, each playing a unique role in managing pain and inflammation. The formulation is designed to be applied topically, directly to the area of discomfort, allowing for targeted treatment and absorption through the skin.

Amitriptyline HCl is a tricyclic antidepressant that is used in this formulation for its analgesic properties. It works by increasing the levels of certain chemicals in the brain that help elevate mood and reduce the sensation of pain. When applied topically, Amitriptyline HCl can help to numb the skin and underlying tissues, reducing pain and discomfort in the applied area.

Baclofen is a muscle relaxer and an antispastic agent. It works by restoring the balance of certain natural substances (such as gamma-aminobutyric acid, GABA) in the brain. Baclofen in this formulation helps to relieve muscle spasms, pain, and stiffness.

Gabapentin is an anticonvulsant and nerve pain medication. It works by calming down nerve activity to reduce pain sensations. Gabapentin in this formulation is used to manage nerve pain, especially in conditions like shingles or diabetic neuropathy.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. Ketoprofen in this formulation is used to reduce inflammation and pain in the area where the gel is applied.

Prilocaine is a local anesthetic that works by blocking nerve signals in your body. It is used in this formulation to numb the skin and tissues underneath, providing temporary relief from pain or discomfort.

Together, these five active ingredients work synergistically to provide relief from various types of pain, including neuropathic pain, musculoskeletal pain, and inflammation. The gel formulation allows for easy and precise application, and the pump mechanism ensures that the correct dose is dispensed each time.

If you have any questions about this formulation, how it works, or how it can be used to manage specific disease states, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Frequently Asked Questions

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What is the Amitriptyline HCl 2%/Baclofen 2%/Gabapentin 5%/Ketoprofen 20%/Prilocaine 2% Topical Gel?

This is a compounded formulation, which is a semisolid creation designed for direct application on the skin. The gel contains active ingredients Amitriptyline HCl, Baclofen, Gabapentin, Ketoprofen, and Prilocaine, each at varying percentages. It is dispensed through a pump for easy and targeted application.

What does 'compounded formulation' mean?

A compounded formulation is a custom-made medication, tailored to meet an individual's specific health needs.

How does the pump mechanism work?

The pump mechanism facilitates easy and precise application of the gel on the skin. It needs to be pressed to dispense the medication.

How should I apply the Amitriptyline HCl 2%/Baclofen 2%/Gabapentin 5%/Ketoprofen 20%/Prilocaine 2% Topical Gel?

Apply the gel to the affected area as per the prescribed dosage by your physician. Usually, this medication is applied and rubbed into the skin.

What is the purpose of the different elements in this compound?

The active ingredients in this compound each have different therapeutic properties. Amitriptyline is an antidepressant, Baclofen is a muscle relaxant/spasmodic, Gabapentin is used to treat nerve pain, Ketoprofen is an anti-inflammatory agent, and Prilocaine is a local anesthetic. Combined together, they work to alleviate pain.

What is the consistency of the gel?

The gel has a semi-solid, gel-like consistency, making it easy to apply to the skin.

Is it suitable for everyone?

Not everyone may be suitable to use this medication. You should talk to your physician before starting any new medication, as there may be potential allergic reactions or interactions with other medications you are taking.

Are there any known side effects?

Possible side effects can range from skin irritation to serious side effects like central nervous system effects. Always inform your physician of any adverse reactions after using the medication.

Can I use it on an open wound?

You should not apply this gel to open wounds or broken skin unless directed by your physician, as this may increase the risk of side effects.

How should this medication be stored?

Generally, this medication should be stored at room temperature away from light and moisture. Always check the label or ask your pharmacist for the specific storage instructions.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Amitriptyline HCl 2%/Baclofen 2%/Gabapentin 5%/Ketoprofen 20%/Prilocaine 2% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Before procedure