This formulation is a compounded topical gel containing Amitriptyline HCl 4%, Baclofen 2%, Bupivacaine HCl 2%, Clonidine HCl 0.2316%, Gabapentin 6%, and Ketamine HCl 11.5%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency aids in the targeted treatment or absorption of the active ingredients.
The combination of these active ingredients is designed to manage various disease states. Amitriptyline HCl is a tricyclic antidepressant used for its analgesic properties, Baclofen is a muscle relaxant and antispasmodic agent, Bupivacaine HCl is a local anesthetic, Clonidine HCl is an alpha-2 adrenergic agonist used for its analgesic and sedative properties, Gabapentin is an anticonvulsant used for neuropathic pain, and Ketamine HCl is an NMDA receptor antagonist used for its analgesic and anesthetic properties.
Together, these ingredients work synergistically to provide relief from symptoms associated with various disease states, including neuropathic pain, muscle spasms, and certain types of chronic pain. The topical application allows for targeted treatment, reducing systemic side effects often associated with oral administration of these medications.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
This compounded formulation contains several active ingredients, each with its own potential for drug interactions. It's important to note that while these interactions are possible, they may not always occur. The risk can depend on individual factors such as the patient's overall health, other medications they are taking, and their specific response to medication. Always consult with a healthcare provider for personalized advice.
Amitriptyline HCl can interact with MAO inhibitors, causing an increase in the effects of both drugs. It can also interact with anticholinergic drugs, leading to increased side effects. Additionally, it can interact with thyroid medications, potentially altering their effectiveness.
Baclofen can interact with other central nervous system depressants, including alcohol, antihistamines, and opioids, potentially increasing drowsiness and respiratory depression. It can also interact with antihypertensive drugs, potentially causing an excessive drop in blood pressure.
Bupivacaine HCl can interact with other local anesthetics or sedative medications, potentially causing an increase in side effects such as drowsiness, dizziness, and slow breathing. It can also interact with certain heart medications, potentially affecting heart rhythm.
Clonidine HCl can interact with beta-blockers, potentially causing a rebound hypertension if either drug is discontinued abruptly. It can also interact with CNS depressants, potentially increasing the risk of side effects such as drowsiness and slow breathing.
Gabapentin can interact with antacids, potentially reducing the absorption of gabapentin. It can also interact with opioid pain medications, potentially increasing the risk of side effects such as drowsiness and slow breathing.
Ketamine HCl can interact with CNS depressants, potentially increasing the risk of side effects such as drowsiness, dizziness, and slow breathing. It can also interact with certain medications for Parkinson's disease, potentially causing an increase in side effects.
This formulation is designed to be applied topically, which can reduce the risk of systemic drug interactions. However, some absorption into the bloodstream can still occur, especially if the medication is applied over large areas of skin, on broken or irritated skin, or under occlusive dressings. Always use this medication as directed by your healthcare provider, and inform them of all other medications you are taking, including prescription, over-the-counter, and herbal products.
This formulation is used to manage various disease states, including neuropathic pain, muscle spasms, and certain types of chronic pain. The combination of active ingredients works to block pain signals, relax muscles, and reduce inflammation, providing targeted relief right where it's needed.
If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us. We're here to help.
This topical gel formulation combines several active ingredients, each with its own unique mechanism of action, to provide a comprehensive approach to pain management. The formulation is designed to be applied directly to the skin, allowing for targeted treatment and absorption of the active ingredients.
Amitriptyline HCl is a tricyclic antidepressant that works by increasing the levels of certain chemicals in the brain that help elevate mood and reduce pain sensation. In a topical formulation, it can provide localized pain relief without the systemic side effects associated with oral administration.
Baclofen is a muscle relaxer and an antispastic agent. It works by restoring the normal transmission of nerve signals in certain parts of the spinal cord, thereby reducing muscle spasms and pain.
Bupivacaine HCl is a local anesthetic that works by blocking nerve impulses in the body, thereby numbing the area to pain. It provides immediate, short-term relief from acute pain.
Clonidine HCl is an alpha-2 adrenergic agonist that works by stimulating receptors in the brain that reduce pain signals from the nerves. It also has a sedative effect which can help to reduce discomfort and anxiety associated with chronic pain.
Gabapentin is an anticonvulsant and nerve pain medication. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. In a topical formulation, it can provide localized relief from neuropathic pain.
Ketamine HCl is a powerful anesthetic that works by blocking the NMDA receptors in the brain, which play a key role in pain signaling. It provides potent, rapid relief from severe or chronic pain.
Together, these ingredients work synergistically to provide comprehensive pain relief. The gel formulation allows for easy and precise application, and the active ingredients are absorbed directly through the skin for targeted treatment. This can be particularly beneficial for patients with localized pain who may not respond well to or cannot tolerate oral pain medications.
If you have any questions about this formulation or how it may benefit you, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.
It is a compounded formulation made of multiple active ingredients intended for topical application on the skin. This formulation is helpful for targeted treatment and is dispensed using a pump mechanism for easy and precise application.
This gel is designed to be applied directly to the skin. The pump mechanism facilitates easy and precise application, simply dispense the desired amount onto the skin and rub it in until absorbed.
This formulation has several active ingredients, including Amitriptyline HCl 4%, Baclofen 2%, Bupivacaine HCl 2%, Clonidine HCl 0.2316%, Gabapentin 6%, and Ketamine HCl 11.5%.
The percentage value indicates the weight of an active ingredient in the total weight of the formulation. Higher percentages indicate a higher concentration of that particular ingredient.
The texture of this gel is semisolid, which makes it easy to apply on the skin and allows it to be absorbed effectively.
Each of the ingredients has a specific therapeutic effect and when combined, they work together to provide a targeted treatment for various medical conditions as prescribed by a healthcare professional.
For optimal effectiveness and longevity, it’s best to store the gel at room temperature, away from direct sunlight. Always refer to the product's label for specific storage instructions.
Before starting any new medication, it is advisable to consult your healthcare provider to avoid potential drug interactions.
Generally, it is well-tolerated on most skin types. However, if you experience any adverse reactions such as redness, itching, or rash, stop using it and seek medical advice immediately.
Like any medication, this topical gel may have potential side effects. It is important to read the product label and consult with your healthcare provider for potential side effects and precautions related to this specific formulation.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.
Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.
Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)