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Baclofen 2%/Diclofenac Sodium 3%/Gabapentin 6%/Ketamine 10%/Lidocaine HCl 5% Topical Gel

Customized by Bayview Pharmacy, this expertly compounded topical gel is designed to help manage neuropathic pain, fibromyalgia, osteoarthritis, and more.
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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Diclofenac Sodium
Gabapentin
Lidocaine Hydrochloride
Baclofen
Ketamine Hydrochloride
Topical Gel
6536f539dbbdb94f6ab233c6

Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Diclofenac Sodium 3%, Gabapentin 6%, Ketamine 10%, and Lidocaine HCl 5%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed effectively for targeted treatment.

Baclofen is a muscle relaxant and antispastic agent that works by calming the nerves and reducing pain. Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that reduces substances in the body that cause pain and inflammation. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain caused by shingles or herpes virus. Ketamine is a general anesthetic that provides pain relief by blocking nerve signals to your brain. Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body, providing numbing relief to the area of application.

This formulation is used to treat a variety of disease states. It can be used to manage chronic pain conditions such as neuropathic pain, fibromyalgia, and complex regional pain syndrome (CRPS). It can also be used to treat acute pain conditions such as post-herpetic neuralgia, musculoskeletal pain, and osteoarthritis. The combination of these five active ingredients provides a multi-modal approach to pain management, targeting different pain pathways to provide comprehensive relief.

Patients should apply the gel to the affected area as directed by their healthcare provider. It is important to wash hands before and after application and to avoid contact with eyes, mouth, and other mucous membranes. Side effects may include skin irritation at the application site, dizziness, drowsiness, or changes in mood or mental state. If these side effects persist or worsen, patients should contact their healthcare provider immediately.

Prescribers should consider this formulation for patients who have not responded to other treatments or who cannot tolerate oral medications due to side effects. It is also a good option for patients who prefer a topical treatment over oral or injectable medications. As with all medications, prescribers should consider the patient's overall health status, other medications, and potential drug interactions before prescribing this formulation.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is here to help.

Drug Interactions

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This compounded formulation contains several active ingredients: Baclofen, Diclofenac Sodium, Gabapentin, Ketamine, and Lidocaine HCl. Each of these medications has its own potential for drug interactions, which can be amplified when used in combination. It's important to note that this formulation is intended for topical use, which may reduce some systemic interactions but does not eliminate them entirely.

Baclofen, a muscle relaxant and antispastic agent, can interact with other central nervous system depressants like alcohol, benzodiazepines, and opioids, potentially leading to increased sedation and respiratory depression. It can also interact with antihypertensive drugs, potentially enhancing their effects and leading to hypotension.

Diclofenac Sodium, a nonsteroidal anti-inflammatory drug (NSAID), can interact with other NSAIDs, increasing the risk of gastrointestinal bleeding. It can also interact with antihypertensive drugs and diuretics, potentially reducing their effectiveness. Additionally, it can increase the risk of nephrotoxicity when used with ACE inhibitors or angiotensin II receptor blockers.

Gabapentin, an anticonvulsant and nerve pain medication, can interact with antacids, reducing the absorption of gabapentin. It can also interact with central nervous system depressants like opioids, benzodiazepines, and alcohol, potentially leading to increased sedation and respiratory depression.

Ketamine, an NMDA receptor antagonist, can interact with other central nervous system depressants, potentially leading to increased sedation and respiratory depression. It can also interact with monoamine oxidase inhibitors (MAOIs), potentially leading to a hypertensive crisis.

Lidocaine HCl, a local anesthetic, can interact with other local anesthetics and antiarrhythmic drugs, potentially leading to additive systemic toxicity. It can also interact with protease inhibitors and cimetidine, potentially increasing the levels of lidocaine in the body.

This formulation is typically used to manage various types of pain, including neuropathic pain, musculoskeletal pain, and post-surgical pain. The combination of these medications works to numb the area, reduce inflammation, and alter the perception of pain, providing a multi-modal approach to pain management.

It's crucial for patients and prescribers to consider all potential drug interactions before starting this medication. Always provide your healthcare provider with a complete list of medications you're taking, including prescription drugs, over-the-counter medications, and dietary supplements. If you have any questions about this formulation or potential drug interactions, don't hesitate to reach out to us at Bayview Pharmacy. We're here to help.

How Does it Work

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This formulation is a combination of five active ingredients: Baclofen, Diclofenac Sodium, Gabapentin, Ketamine, and Lidocaine HCl. Each of these ingredients plays a unique role in managing pain and inflammation, and their combined effect can provide significant relief for a variety of disease states.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to reduce muscle spasms, pain, and stiffness.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. It is often used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis.

Gabapentin is an anticonvulsant that is often used to treat nerve pain. It works by stabilizing electrical activity in the brain and also affects the way the body senses pain.

Ketamine is a general anesthetic that provides pain relief by blocking certain receptors in the brain. It has a unique ability to provide analgesia without causing respiratory depression, which is a common side effect of other pain medications.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. It is often used to relieve pain or discomfort caused by skin irritations such as sunburn, insect bites, poison ivy, poison oak, poison sumac, and minor cuts, scratches, or burns.

The semisolid formulation dispensed through a pump mechanism allows for easy and precise application on the skin. This targeted treatment allows for the active ingredients to be absorbed directly into the affected area, providing localized relief without the systemic side effects that can occur with oral medications.

This formulation can be used to treat a variety of disease states that involve pain and inflammation, including but not limited to neuropathic pain, musculoskeletal pain, post-herpetic neuralgia, fibromyalgia, and certain types of chronic pain conditions.

If you have any questions about this formulation, how it works, or how it can be used to treat specific disease states, please don't hesitate to reach out to us. We are here to help and provide you with the information you need to make informed decisions about your health.

Other Uses

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This formulation is primarily recommended to treat various forms of nerve pain and used for its antispasmodic, anti-inflammatory, and anesthetic effects. However, different active ingredients within the formulation make it versatile, having potential applications beyond just nerve-related pain and inflammation. These uses, nevertheless, should always be discussed with a healthcare provider prior to use.

Baclofen, for instance, a potent muscle relaxant and antispasmodic agent, may also have benefits for patients struggling with muscle spasms or cramps outside of a direct nerve injury context. Its ability to lessen muscle stiffness could potentially be beneficial in conditions like cerebral palsy and multiple sclerosis, as well as maintaining muscle mobility in certain muscular disorders.

Diclofenac Sodium is a nonsteroidal anti-inflammatory drug (NSAID), which can lend its anti-inflammatory properties not only to conditions related to nerve inflammation but also to general inflammation or discomfort arising from sprains, strains, arthritis, and more.

Gabapentin contributes to the formula's efficacy against neuropathy, but may also offer pain relief for postherpetic neuralgia, restless leg syndrome, and hot flashes. Ketamine, a well-known NMDA receptor antagonist, can often provide deep pain relief for various kinds of chronic pains extending beyond neuropathy.

Lidocaine HCl doesn't just assist with nerve pain - it also acts as a local anesthetic. This means it may provide temporary numbing relief for skin irritations, burns, bites, and even surface-level pain from certain medical procedures, tattooing, or piercing.

However, it is crucial to keep in mind that these "other uses" are dependent on a variety of factors, including other medications being taken, overall health status, and the specific goals of treatment. Always have any new potential use of this formulation approved by a healthcare professional to ensure appropriate treatment, while minimizing potential adverse effects. For any questions or further information on this or any other formulations, feel free to reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is the compounded formulation of Baclofen 2%/Diclofenac Sodium 3%/Gabapentin 6%/Ketamine 10%/Lidocaine HCl 5% Topical Gel?

This is a semisolid formulation consisting of Baclofen, Diclofenac Sodium, Gabapentin, Ketamine, and Lidocaine HCl. It is designed for easy and precise application on the skin for targeted treatment or absorption of these active ingredients.

How should this topical gel be used?

The gel should be applied directly on the skin. It's a semisolid formulation that can be dispensed through a pump mechanism for easy application.

What are the active ingredients in the topical gel?

The active ingredients in the gel include Baclofen, Diclofenac Sodium, Gabapentin, Ketamine, and Lidocaine HCl. These are combined in specific proportions to ensure maximum effectiveness.

Is the use of this gel painful?

No, the gel includes an agent, Lidocaine HCl, which provides local anesthesia reducing any potential discomfort at the site of application.

How does a pump mechanism aid in application?

The pump mechanism allows for an easy, clean, and precise application of the gel. This ensures that the right amount of gel is applied to the targeted area.

What is the consistency of this gel?

This compounded formulation has a gel-like consistency which renders it easy to apply and fast absorbing into the skin.

What is the purpose of each active ingredient in the formulation?

Baclofen is a muscle relaxant and antispasmodic agent, Diclofenac Sodium is a nonsteroidal anti-inflammatory drug, Gabapentin is used to relieve nerve pain, Ketamine is a potent analgesic, and Lidocaine HCl provides local anesthetic effect.

Can this gel be used for any kind of pain?

The compounded gel formulation is specifically designed for targeted local treatment and may not be suitable for all kinds of pain. Consultation with a healthcare provider is recommended to determine its suitability for specific conditions.

How long does it take for the gel to work?

The onset of action can vary depending upon the specific condition and the individual's response to the medication. However, relief is usually observed shortly after the application.

Are there any side effects of this gel?

Like all medicines, this gel can also cause side effects, though not everybody gets them. Possible side effects may include redness or irritation at the site of application. Always inform your healthcare provider if you experience any adverse reactions after using this gel.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Related Formulas

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
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Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Baclofen 2%/Diclofenac Sodium 3%/Gabapentin 6%/Ketamine 10%/Lidocaine HCl 5% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)