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Cyclobenzaprine 5%/Diclofenac 1%/Gabapentin 5%/Lidocaine 2% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Gabapentin
Cyclobenzaprine Hydrochloride
Diclofenac Sodium
Lidocaine Hydrochloride

This formulation is a combination of Cyclobenzaprine 5%, Diclofenac 1%, Gabapentin 5%, and Lidocaine 2% in a topical gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is designed to treat a variety of disease states. Cyclobenzaprine, a muscle relaxant, is used to relieve muscle spasms and pain. Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID), is used to reduce inflammation and pain. Gabapentin is used to manage nerve pain and seizures, while Lidocaine, a local anesthetic, provides temporary relief from pain and discomfort.

Together, these ingredients work synergistically to provide relief from conditions such as neuropathic pain, musculoskeletal pain, inflammation, and certain types of seizures. This formulation is particularly beneficial for patients seeking targeted, topical relief from these conditions.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Gabapentin
Cyclobenzaprine Hydrochloride
Diclofenac Sodium
Lidocaine Hydrochloride
Topical Gel
653f3fdfedf440d4b30bbd03
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This formulation is a compounded topical gel containing Cyclobenzaprine 5%, Diclofenac 1%, Gabapentin 5%, and Lidocaine 2%. It is designed to be dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed effectively into the skin for targeted treatment.

Cyclobenzaprine is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces substances in the body that cause pain and inflammation. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain caused by shingles (herpes zoster). Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.

The anti-inflammatory properties of Diclofenac can help to reduce inflammation and pain in conditions such as osteoarthritis and rheumatoid arthritis. The muscle relaxant properties of Cyclobenzaprine can help to relieve muscle spasms and associated pain. Gabapentin can help to manage nerve pain, while Lidocaine provides immediate, temporary relief from pain or discomfort.

It's important to note that this formulation is intended for topical use only and should not be ingested or applied to open wounds or damaged skin. As with any medication, it's crucial to use this formulation as directed by your healthcare provider. Side effects can include skin irritation or sensitivity at the application site. If you experience any unusual or severe side effects, contact your healthcare provider immediately.

If you have any questions about this formulation, its uses, or its potential side effects, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Drug Interactions

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This compounded formulation contains four active ingredients: Cyclobenzaprine, Diclofenac, Gabapentin, and Lidocaine. Each of these medications has its own potential for drug interactions, which can be amplified when used in combination. It's important to note that while this is a topical formulation, systemic absorption can still occur, especially with prolonged use or application to large areas of skin.

Cyclobenzaprine is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It may interact with monoamine oxidase inhibitors (MAOIs), increasing the risk of serious side effects such as high fever, severe headache, stiff neck, nausea, vomiting, rapid heartbeat, and changes in blood pressure. It may also interact with other medications that cause drowsiness such as antihistamines, opioids, sleeping pills, and alcohol.

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces substances in the body that cause pain and inflammation. It may interact with other NSAIDs, increasing the risk of stomach ulcers and bleeding. It may also interact with blood thinners, high blood pressure medications, and certain heart medications. Diclofenac should not be used in the last 3 months of pregnancy as it may harm the unborn baby.

Gabapentin is an anticonvulsant and nerve pain medication. It may interact with antacids containing aluminum or magnesium, as they can reduce the amount of gabapentin that the body absorbs. It may also interact with opioids, increasing the risk of serious side effects such as shallow breathing, severe drowsiness, and dizziness.

Lidocaine is a local anesthetic that works by blocking nerve signals in your body. It may interact with other local anesthetics and medications used to treat irregular heart rhythms. Excessive use of lidocaine can lead to systemic toxicity, resulting in symptoms such as seizures, slow heart rate, and low blood pressure.

This formulation is designed to treat conditions such as neuropathic pain, muscle spasms, and inflammation. The combination of these medications allows for targeted treatment, potentially reducing the need for systemic medications and their associated side effects. However, it's important to use this medication as directed by your healthcare provider and to inform them of all other medications you are currently taking, including over-the-counter medications and supplements.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us at Bayview Pharmacy.

How Does it Work

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This unique formulation combines four active ingredients: Cyclobenzaprine, Diclofenac, Gabapentin, and Lidocaine, each with a specific role in managing pain and inflammation. The gel is designed to be applied topically, directly to the skin, where it can be absorbed and exert its effects locally. This method of administration can help to minimize systemic side effects that can occur with oral medications.

Cyclobenzaprine is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that reduces substances in the body that cause pain and inflammation. It is commonly used to treat mild to moderate pain, or signs and symptoms of osteoarthritis or rheumatoid arthritis.

Gabapentin is a medication that is primarily used to treat seizures and neuropathic pain. It is believed to work by altering electrical activity in the brain and influencing the activity of chemicals that send signals in the nervous system. In this formulation, it can help to alleviate nerve pain. Lidocaine is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. It works by blocking nerve signals in your body and is used to reduce pain or discomfort caused by skin irritations.

When combined in a gel formulation, these four ingredients can provide comprehensive pain relief by addressing different aspects of the pain response. The gel formulation allows for targeted application, meaning it can be applied directly to the area of pain. Furthermore, the pump mechanism allows for easy and precise dosing, ensuring that the correct amount of medication is applied each time.

If you have any questions about this formulation, how it works, or how it can be used to treat specific conditions, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is always here to help.

Other Uses

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While primarily prescribed for treating muscle spasms, inflammation, nerve pain, and local pain, this compounding formulation of Cyclobenzaprine, Diclofenac, Gabapentin, and Lidocaine has some other potential therapeutic uses. One of these is in the management of neuropathic pain disorders such as diabetic peripheral neuropathy. Given the gel's targeted nature, it can be applied directly to the area of discomfort, providing potential relief without the systemic side effects common to oral medications.

Some studies suggest a role for this topical formulation in managing certain types of headaches, particularly those with a significant muscular or neuropathic component. Besides, the formulation's anti-inflammatory component, namely Diclofenac, might make it beneficial for conditions such as osteoarthritis or other inflammatory pain conditions. Here the direct application might minimize the risk of gastrointestinal issues, often linked to oral NSAIDs.

As such, both patients and prescribers should note that the formulation's use outside of its primary indications is still evolving. It's crucial to maintain open discussion on the patient’s ongoing symptoms, response to treatment, and any adverse effects.

We might add that all use of this formulation should be under the guidance of a healthcare provider, as these are prescription medications with their own set of possible side effects and interactions. If you have more specific questions or need additional details about this formulation and its potential therapeutic uses, don't hesitate to reach out to us at Bayview Pharmacy.

Frequently Asked Questions

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What is this formulation of Cyclobenzaprine 5%/Diclofenac 1%/Gabapentin 5%/Lidocaine 2% Topical Gel used for?

This compounded formulation is used to deliver targeted relief from various types of pain including muscle pain, nerve pain, and inflammation. These specific active ingredients work in combination to alleviate discomfort and promote healing.

How is this topical gel dispensed and applied?

The gel is dispensed through a pump mechanism which allows for easy and precise application onto the skin. Simply pump the desired amount onto your hand and apply it to the targeted area.

Does the gel leave any residue on the skin?

The gel is formulated to be easily absorbed through the skin, thus minimizing any residue. However, individuals may experience varying rates of absorption due to factors like skin types and the exact location of application.

Can this formulation be applied at any time of the day?

Yes, this topical gel can be applied at any time of the day. However, it is recommended to follow the prescription or advice of a healthcare professional.

Can this formulation be used concurrently with other medications?

Concurrent use of this formulation with other medications depends primarily on the nature of those medicines. Always consult your healthcare professional before starting to use new medication, including topical gels.

Are there any side effects related to the use of this compounded formulation?

As with any medication, side effects may occur. Possible side effects may include skin irritation or allergic reactions. Contact your healthcare provider immediately if you experience any adverse reactions.

Is it necessary to clean the skin before applying this topical gel?

Yes, it is generally advisable to clean the skin before application for the gel to be properly absorbed and to prevent infection or irritation from dirt or debris.

Is this formulation safe for all skin types?

Generally, this formulation is designed to be safe for most skin types. However, individuals with extremely sensitive skin or certain skin conditions should consult a healthcare professional before use.

Can I apply this formulation on broken or irritated skin?

No. You should avoid applying this formulation on broken, damaged or irritated skin as it might cause further irritation or systemic absorption might occur.

How should this formulation be stored?

In general, it should be stored at room temperature, away from heat and direct sunlight. Additionally, keep it out of reach of children and pets.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Cyclobenzaprine 5%/Diclofenac 1%/Gabapentin 5%/Lidocaine 2% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily