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Cyclobenzaprine HCl 2%/Gabapentin 4%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Cyclobenzaprine Hydrochloride
Gabapentin
Ketoprofen
Lidocaine Hydrochloride

This formulation is a combination of Cyclobenzaprine HCl 2%, Gabapentin 4%, Ketoprofen 10%, and Lidocaine HCl 5% in a topical gel. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is used to treat a variety of disease states. Cyclobenzaprine HCl is a muscle relaxant that helps to relieve muscle spasms, Gabapentin is used to manage nerve pain, Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation, and Lidocaine HCl is a local anesthetic that causes temporary numbness or loss of sensation in the area of application.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Cyclobenzaprine Hydrochloride
Gabapentin
Ketoprofen
Lidocaine Hydrochloride
Topical Gel
653fa1b910502d604fa2d79f

Formula Information

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This formulation is a compounded topical gel containing Cyclobenzaprine HCl 2%, Gabapentin 4%, Ketoprofen 10%, and Lidocaine HCl 5%. It is a semisolid formulation that is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency of the formulation ensures that the active ingredients are absorbed effectively into the targeted area.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain conditions. It works by stabilizing electrical activity in the brain and also affects the way the body senses pain. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination of medications in a topical gel form allows for targeted treatment of various disease states.

This formulation is particularly useful in treating conditions such as neuropathic pain, musculoskeletal pain, inflammation, and localized nerve pain. The combination of these medications allows for a multi-modal approach to pain management, addressing different aspects of pain perception and inflammation. The topical application allows for targeted treatment, reducing systemic side effects often associated with oral medications. It is important to use this medication as directed by your healthcare provider, and it should not be used on broken or irritated skin.

As with any medication, there may be potential side effects, and it is important to discuss these with your healthcare provider. These may include skin irritation at the application site, and more rarely, systemic side effects such as dizziness or nausea. It is important to inform your healthcare provider of all medications you are currently taking, as there may be potential interactions.

If you have any questions about this formulation, please do not hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you with any questions or concerns you may have.

Drug Interactions

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This formulation contains a combination of Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. Each of these active ingredients has its own potential for drug interactions, which can be amplified when used in combination. It's important for patients and prescribers to be aware of these potential interactions to ensure safe and appropriate use of this medication.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It may interact with monoamine oxidase inhibitors (MAOIs), increasing the risk of serious side effects such as high body temperature, high blood pressure, muscle rigidity, and severe nervous system problems. It may also interact with other medications that cause drowsiness such as benzodiazepines, opioids, and antihistamines.

Gabapentin is an anticonvulsant and nerve pain medication. It may interact with antacids containing aluminum or magnesium, as they can reduce the amount of gabapentin that the body absorbs. It can also increase the effects of certain drugs that slow brain processes, such as barbiturates, benzodiazepines, and narcotics.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. It may interact with blood thinners, other NSAIDs, and corticosteroids, increasing the risk of gastrointestinal bleeding. It may also interact with ACE inhibitors, angiotensin II receptor blockers, or diuretics, potentially reducing their effectiveness.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. It may interact with other local anesthetics and medications used to treat irregular heart rhythms. It can also interact with certain antibiotics, antifungal medications, and heart or blood pressure medications.

This formulation is designed to treat a variety of disease states. Cyclobenzaprine HCl is used to relieve muscle spasms, Gabapentin is used to treat nerve pain, Ketoprofen is used to reduce inflammation and pain, and Lidocaine HCl is used to numb the skin and relieve pain. The combination of these medications in a topical gel allows for targeted treatment and absorption of the active ingredients.

If you have any questions about this formulation or potential drug interactions, please don't hesitate to reach out to us at Bayview Pharmacy.

How Does it Work

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This formulation is a combination of four active ingredients: Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl, each playing a unique role in managing pain and inflammation. The formulation is designed to be applied topically, directly to the skin, where it can be absorbed to provide targeted relief.

Cyclobenzaprine HCl is a muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. When applied topically, it can provide targeted relief to the affected area.

Gabapentin is a medication primarily used to treat seizures and neuropathic pain. It works by affecting the chemicals and nerves in the body that are involved in the cause of seizures and some types of pain. In this formulation, it helps to reduce the sensation of pain in the area where the gel is applied.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body. When applied topically, Ketoprofen can directly target areas of inflammation, reducing pain and swelling.

Lidocaine HCl is a local anesthetic that works by causing temporary numbness in the area where it is applied. It works by blocking nerve signals in your body and is often used to relieve pain and discomfort caused by skin irritations, sore throats, sunburn, teething pain, vaginal or rectal irritation, ingrown toenails, hemorrhoids, and many other sources of minor pain on the surface of the body.

The gel formulation allows for easy and precise application of these medications directly to the area of pain or inflammation. The gel is absorbed through the skin, allowing the active ingredients to work directly on the affected area. This can provide more targeted relief than oral medications, which must be absorbed through the digestive system and distributed throughout the entire body.

If you have any questions about this formulation, how it works, or how it can be used to treat specific conditions, please don't hesitate to reach out to us. We are here to help and provide you with the information you need to make informed decisions about your health.

Other Uses

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This multi-ingredient compound gel formulation is primarily used to manage localized pain and discomfort arising from various medical conditions. However, beyond this, the formulation possesses other notable uses. The gel's individual components - Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl - all possess their unique therapeutic properties which provide potential additional uses.

Cyclobenzaprine HCl is typically used as a muscle relaxant and can also be applied topically to alleviate muscle spasms or related discomfort. Gabapentin, traditionally administered for nerve pain and seizures, when used in topical form, can potentially soothe neuropathic pain in a target area. Ketoprofen is often employed as an NSAID for relieving inflammation, but may also help diminish pain from other inflammation-associated conditions when applied topically. Lidocaine HCl is commonly recognized as a local anesthetic and might be used in managing pruritus, minor burns or insect bites, by numbing the affected skin area.

The gel's secondary uses are subject to the individual patient's context and health conditions and should ideally be used under a healthcare professional's advice. The delivery system, being a pump mechanism, allows for convenient application and accurate dosage. Also, being a gel, it spreads smoothly, maximizes skin contact, and may offer faster and targeted relief, and potentially be useful in managing localized conditions, beyond the noted uses.

Patient's comfort is crucial, and topically applied formulations are usually well-tolerated and have less systemic side effects. However, skin sensitivity or allergic reactions can occur and should be promptly reported to a healthcare provider. Individuals with specific skin conditions or those on certain medications might need to consult their healthcare provider before using this compound gel to avoid interactions or side effects. All product usage must be as per a healthcare provider's direction, and this formulation is not meant to substitute or sidestep any ongoing therapeutic regimens.

If you have any questions or need further clarification about this formulation, its additional uses or any other related matter, please feel free to reach out to our knowledgeable compounding pharmacists at Bayview Pharmacy. We are here to assist with expert insights and trustworthy advice grounded in science and patient safety.

Frequently Asked Questions

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What exactly is the compounded formulation of Cyclobenzaprine HCl 2%/Gabapentin 4%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel?

This is a specially compounded product that contains four active ingredients: Cyclobenzaprine, Gabapentin, Ketoprofen, and Lidocaine. It's a semisolid formulation that has a gel-like consistency, which is applied on the skin for targeted treatment or absorption of these ingredients.

How does the pump mechanism work?

The pump mechanism on the bottle ensures easy and precise application of the gel. When you press down on the pump, it releases a measured quantity of the formulation, allowing for consistent, accurate dosing.

What are the benefits of this compound formulation?

The combination of these four ingredients can provide greater pain relief than any single ingredient alone. Moreover, by delivering the ingredients transdermally (through the skin), systemic side effects can be significantly reduced.

How should I use this topical formulation?

You apply the gel to your skin in the area as advised by the healthcare provider. The strength and absorption of the gel can vary based on the instructions given by the healthcare provider or pharmacist.

Is it safe to use on broken or damaged skin?

Unless specifically advised by your healthcare provider, avoid applying this compound cream on broken or damaged skin because it might lead to unexpected absorption and side effects.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it's near the time for your next dose, then skip the missed one and go back to your regular schedule. Do not use double doses.

Can I apply this topical gel anywhere on my body?

No. Only apply the gel to the areas advised by your healthcare provider. Avoid contact with areas like your eyes, nose, and mouth.

What should I do if the product gets in my eyes or mouth?

In case the gel gets in your eyes or mouth accidently, rinse with plenty of water and contact your healthcare provider immediately.

Can this compound formulation cause allergic reactions?

Some people may have an allergic reaction to one or more of the ingredients in the compound. If you develop an unusual or allergic reaction, stop using the formulation and contact your healthcare provider immediately.

Can I use this topical gel if I am pregnant or nursing?

If you are pregnant, planning a pregnancy or nursing, consult your healthcare provider before using any new medications including topical formulations.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Cyclobenzaprine HCl 2%/Gabapentin 4%/Ketoprofen 10%/Lidocaine HCl 5% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)