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Ketoprofen 10%/Ketamine HCl 5%/Amitriptyline HCl 2%/Baclofen 2% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Ketoprofen
Ketamine Hydrochloride
Amitriptyline Hydrochloride
Baclofen

This topical gel is a compounded formulation of ketoprofen 10%, ketamine HCl 5%, amitriptyline HCl 2%, and baclofen 2%. It is dispensed through a pump mechanism, allowing for easy and precise application. The gel-like consistency ensures targeted treatment or absorption of the active ingredients. It is commonly used for conditions such as fibromyalgia, neuropathic pain, osteoarthritis, rheumatoid arthritis, and migraine headaches.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Ketoprofen
Ketamine Hydrochloride
Amitriptyline Hydrochloride
Baclofen
Topical Gel
6427079ea643246cdb518cff

Formula Information

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Bayview Pharmacy is pleased to present a specialized topical gel formulation of Ketoprofen 10%/Ketamine HCl 5%/Amitriptyline HCl 2%/Baclofen 2%. This unique blend is specifically designed to alleviate a range of conditions, including musculoskeletal pain, neuropathic pain, and spasticity.

Ketoprofen, a non-steroidal anti-inflammatory drug (NSAID), functions by inhibiting the production of certain body chemicals that trigger inflammation and pain. Ketamine HCl, an anesthetic, operates by blocking the transmission of pain signals to the brain. Amitriptyline HCl, a tricyclic antidepressant, works by preventing the reuptake of specific neurotransmitters, such as serotonin and norepinephrine, which can aid in pain reduction. Baclofen, a muscle relaxant, functions by obstructing the transmission of nerve signals to the muscles, which can help alleviate spasticity.

This topical gel formulation is a semisolid preparation dispensed through a pump mechanism, facilitating easy and precise application on the skin for targeted treatment or absorption of active ingredients in a gel-like consistency. Its ease of application provides relief from pain and spasticity without the necessity for oral medications.

If you have any inquiries about this formulation or how it can assist in treating your condition, please do not hesitate to contact us at Bayview Pharmacy. Our team of experienced compounding pharmacists is always ready to provide the necessary guidance and support.

Drug Interactions

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Ketoprofen 10%/Ketamine HCl 5%/Amitriptyline HCl 2%/Baclofen 2% Topical Gel is a compounded formulation designed for the treatment of pain, inflammation, and muscle spasms associated with various disease states. This semisolid formulation is dispensed through a pump mechanism, allowing for easy and precise application on the skin for targeted treatment or absorption of active ingredients in a gel-like consistency.

The formulation contains four active ingredients: Ketoprofen, Ketamine HCl, Amitriptyline HCl, and Baclofen. Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) that works by blocking the production of prostaglandins, substances in the body that cause inflammation and pain. Ketamine HCl is an anesthetic that works by blocking the transmission of pain signals to the brain. Amitriptyline HCl is a tricyclic antidepressant that works by blocking the reuptake of serotonin and norepinephrine, neurotransmitters that can help reduce pain and inflammation. Baclofen is a muscle relaxant that works by blocking the transmission of nerve signals to the muscles, helping to reduce muscle spasms.

However, this formulation should not be used in patients with known hypersensitivity to any of the components. Additionally, caution should be exercised when using this formulation in patients with a history of cardiovascular disease, as ketoprofen may increase the risk of cardiovascular events.

It is important to consult with a healthcare provider before starting any new medication, including this compounded formulation. If you have any questions about the use of this formulation, please consult with your healthcare provider.

How Does it Work

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Ketoprofen 10%/Ketamine HCl 5%/Amitriptyline HCl 2%/Baclofen 2% Topical Gel is a compounded formulation designed to provide targeted relief from pain and inflammation. This unique blend of four active ingredients works synergistically to address various aspects of pain and discomfort.

Ketoprofen, a potent anti-inflammatory drug, works by inhibiting the production of certain chemicals in the body that trigger inflammation. Ketamine HCl, an anesthetic, functions by blocking the transmission of pain signals to the brain, thereby reducing the perception of pain. Amitriptyline HCl, an antidepressant, enhances the levels of specific chemicals in the brain that help alleviate pain and improve mood. Lastly, Baclofen, a muscle relaxant, operates by blocking nerve signals to the muscles, thereby helping to alleviate muscle spasms and pain.

When applied topically, this compounded formulation can provide relief from pain and inflammation associated with a range of conditions. These include but are not limited to arthritis, bursitis, tendonitis, and other musculoskeletal disorders.

To use this formulation, apply a thin layer of the gel to the affected area and gently massage it in until it is fully absorbed. The gel should be applied two to three times daily, or as directed by your healthcare provider. It is crucial to wash your hands after applying the gel to prevent the inadvertent spread of the medication to other areas of the body.

If you have any questions or concerns about using this formulation, please do not hesitate to reach out.

Other Uses

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This compounded formulation of Ketoprofen 10%/Ketamine HCl 5%/Amitriptyline HCl 2%/Baclofen 2% is a semisolid topical gel that is dispensed through a pump mechanism. This allows for easy and precise application on the skin, targeting the treatment area directly and facilitating the absorption of the active ingredients. The gel-like consistency ensures a smooth application process.

The formulation is a versatile treatment option for a wide range of conditions. It is also beneficial for other musculoskeletal conditions such as tendinitis, bursitis, and myofascial pain.

Moreover, this formulation can be used to treat chronic pain conditions like complex regional pain syndrome (CRPS) and post-herpetic neuralgia. It is also useful in addressing chronic itch conditions such as prurigo nodularis and pruritus ani. The formulation can be used to manage chronic headaches, including tension-type headaches and cluster headaches.

Furthermore, it can be used to treat chronic pelvic pain conditions such as endometriosis and interstitial cystitis. If you have any questions about the use of this formulation for any of these conditions, please reach out to a healthcare professional for guidance.

Frequently Asked Questions

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What is the purpose of this compounded formulation?

This compounded formulation is designed to provide targeted treatment for pain and inflammation. The active ingredients - Ketoprofen, Ketamine HCl, Amitriptyline HCl, and Baclofen - work together to provide relief from symptoms.

How do I use this topical gel?

This gel is dispensed through a pump mechanism for easy and precise application. Simply apply it to the affected area of the skin as directed by your healthcare provider.

What is the consistency of this gel?

The gel has a semisolid formulation, which means it is not as liquid as a lotion but not as solid as a cream. It is designed to be easily spreadable on the skin.

Can this gel be used for any type of pain?

This gel is typically used for localized pain and inflammation. However, it's important to use it as directed by your healthcare provider, who will determine if it's suitable for your specific condition.

What are the active ingredients in this gel?

The active ingredients in this gel are Ketoprofen 10%, Ketamine HCl 5%, Amitriptyline HCl 2%, and Baclofen 2%.

How does the pump mechanism work?

The pump mechanism allows for easy and precise dispensing of the gel. Simply press down on the pump to dispense the gel, then apply it to the skin.

Can I use this gel if I have sensitive skin?

If you have sensitive skin, it's important to discuss this with your healthcare provider before using this gel. They can provide guidance on whether this product is suitable for you.

How often should I apply this gel?

The frequency of application will depend on your specific condition and the instructions provided by your healthcare provider. Always follow their directions for use.

What should I do if I experience any side effects?

If you experience any side effects, such as skin irritation or an allergic reaction, stop using the gel and contact your healthcare provider immediately.

Can I use this gel with other medications?

Before using this gel with other medications, it's important to discuss it with your healthcare provider. They can provide guidance on whether it's safe to use with other treatments.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Ketoprofen 10%/Ketamine HCl 5%/Amitriptyline HCl 2%/Baclofen 2% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)