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Baclofen 1%/Cyclobenzaprine HCl 1%/Gabapentin 3%/Ketoprofen 10%/Lidocaine HCl 4% Topical Gel

Custom-compounded at Bayview Pharmacy, this topical gel combines Baclofen, Cyclobenzaprine, Gabapentin, Ketoprofen, and Lidocaine to help manage neuropathic pain, muscle spasms, and osteoarthritis.
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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Cyclobenzaprine Hydrochloride
Gabapentin
Ketoprofen
Lidocaine Hydrochloride
Baclofen
Topical Gel
65357b2b330c4e2c6515eef4

Formula Information

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This formulation is a compounded topical gel containing Baclofen 1%, Cyclobenzaprine HCl 1%, Gabapentin 3%, Ketoprofen 10%, and Lidocaine HCl 4%. It is a semisolid formulation that is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed directly into the targeted area, providing localized relief.

Baclofen is a muscle relaxant and antispastic agent that helps to relieve muscle spasms, tightness, and pain. Cyclobenzaprine HCl is another muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain conditions. Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that reduces hormones that cause inflammation and pain in the body. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes.

It can be used to manage pain and inflammation associated with conditions such as arthritis, fibromyalgia, neuropathic pain, and musculoskeletal disorders. The muscle relaxants in the formulation can help to alleviate muscle spasms and tightness, while the NSAID and local anesthetic provide relief from pain and inflammation.

It's important to note that this formulation is intended for topical use only and should not be ingested or applied to open wounds or damaged skin. As with any medication, it's crucial to use this formulation as directed by your healthcare provider. Side effects may include skin irritation or sensitivity at the application site. If you experience any unusual or severe side effects, contact your healthcare provider immediately.

If you have any questions about this formulation or how to use it, don't hesitate to reach out to us at Bayview Pharmacy. Our knowledgeable team of compounding pharmacists is always here to help.

Drug Interactions

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This topical gel formulation combines Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. These active ingredients work synergistically to provide pain relief, muscle relaxation, and anti-inflammatory effects. This formulation is particularly useful in treating conditions such as neuropathic pain, muscle spasms, and inflammation associated with conditions like fibromyalgia, post-herpetic neuralgia, and certain types of arthritis.

While this formulation is designed to minimize systemic absorption and thus reduce the risk of drug interactions, it is still important to be aware of potential interactions with other medications you may be taking. Here are some key interactions to be aware of:

Baclofen: May enhance the adverse/toxic effect of other Central Nervous System Depressants. Monitor therapy.

Cyclobenzaprine: May enhance the serotonergic effect of Serotonin Modulators. This could result in serotonin syndrome. Monitor therapy.

Gabapentin: May enhance the adverse/toxic effect of other CNS Depressants. Monitor therapy.

Ketoprofen: May enhance the adverse/toxic effect of other Nonsteroidal Anti-Inflammatory Agents. Monitor therapy.

Lidocaine: May enhance the adverse/toxic effect of other Local Anesthetics. Monitor therapy.

It's important to inform your healthcare provider of all medications you are currently taking, including prescription drugs, over-the-counter medications, and dietary supplements. This will help your healthcare provider to monitor for drug interactions and adjust your treatment plan accordingly.

As with any medication, it's important to use this formulation as directed by your healthcare provider. If you experience any adverse effects or have any concerns, contact your healthcare provider immediately. This formulation should not be used by individuals with known hypersensitivity to any of the active ingredients.

If you have any questions about this formulation or its use, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to provide you with the information and support you need to manage your health effectively.

How Does it Work

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This formulation is a combination of five active ingredients: Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. Each of these ingredients plays a unique role in managing pain and inflammation, and their combined effect can provide significant relief for a variety of disease states.

Baclofen is a muscle relaxant and antispastic agent. It works by inhibiting the transmission of reflexes at the spinal level, which can help to reduce muscle spasms, pain, and stiffness.

Cyclobenzaprine HCl is another muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain.

Gabapentin is an anticonvulsant and nerve pain medication. It works by affecting the chemicals and nerves in your body that are involved in the cause of seizures and some types of pain.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.

Lidocaine HCl is a local anesthetic. It works by blocking nerve signals in your body, which can help to numb the area and reduce pain and discomfort.

When applied topically, this formulation allows for targeted treatment. The active ingredients are absorbed through the skin directly to the area of pain or inflammation.

This formulation can be used to treat a variety of disease states, including but not limited to: muscle spasms, nerve pain, arthritis, and other conditions that involve pain and inflammation. It is important to use this medication as directed by your healthcare provider, and to discuss any questions or concerns you may have with them.

If you have any questions about this formulation, please don't hesitate to reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Other Uses

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This formulation is primarily used to manage and alleviate pain, especially in patients with conditions like fibromyalgia, neuralgia, diabetic neuropathy, and musculoskeletal pain due to the presence of Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. These ingredients work together to reduce nerve pain, inflammation, and muscle spasms.

Apart from these, the formulation may also find off-label use in the management of other forms of chronic and acute pain. For instance, the anti-inflammatory properties of Ketoprofen may help patients with osteoarthritis or rheumatoid arthritis. Lidocaine HCl's local anesthetic properties might be beneficial in relieving pruritus (itching), burning sensation, or pain associated with conditions like shingles. Gabapentin may be used for treating restless legs syndrome and hot flashes.

In terms of patient information, it is essential to note that this medication should be used externally only. It should be applied to the affected area as per the recommendations of the healthcare professional. Patients should thoroughly wash their hands after each application, unless the hands are the area being treated. Instances of adverse reactions or side effects should be reported to a healthcare provider immediately.

For prescribers, it is vital to mention any contraindications or potential interactions that a patient may have with the compounds in this formulation. It is also important to instruct patients on the correct usage, frequency of application, and what to do in case of missed doses to maximize the therapeutic benefits.

Please reach out to us if there are any questions or if more specific information is needed.

Frequently Asked Questions

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What is the purpose of the Baclofen 1%/Cyclobenzaprine HCl 1%/Gabapentin 3%/Ketoprofen 10%/Lidocaine HCl 4% Topical Gel?

This topical gel is a semi-solid formulation designed to provide easy and precise application of active ingredients via a pump mechanism on the skin. It is indicated for the treatment of targeted areas with symptoms such as pain and inflammation.

How does the gel consistency affect application?

The gel-like consistency helps facilitate easy application, allowing for precise and controlled dispensation of medication through the pump mechanism. Its semi-solid form also aids in maintaining contact with the skin for effective absorption of the active ingredients.

How is this medication applied?

This medication is applied topically to the skin, meaning you apply it to the area of your body in need of treatment. The pump mechanism allows for simple and precise dispersion of the gel on the skin.

Does this topical gel have any side effects?

As with any medication, there can be potential side effects. These may include skin irritation or allergic reactions. If you notice any adverse effects, you should contact your healthcare provider immediately.

What are the precautions when using this gel?

This gel should be used exactly as directed by your healthcare professional. Avoid contact with eyes or open wounds. Do not ingest this product as it is intended for topical use only. Always wash your hands thoroughly before and after application.

Can this gel be used with other medications?

Always inform your healthcare provider about all the medications you are currently using, including over-the-counter drugs, prescription medicines, and dietary supplements. They can provide guidance on whether it's safe to use this gel in conjunction with other medications.

Is this gel safe for all age groups?

This information should be provided by your healthcare provider, as suitability can depend on an individual's overall health status, age, and other factors. It is always important to follow the provided directions and to seek professional advice if you have any concerns.

How should this medication be stored?

This gel should be stored in a cool, dry place, away from direct sunlight. Ensure the lid is tightly sealed when not in use to prevent drying out.

What do I do if I miss a dose?

If you miss a dose of this medication, apply it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and return to your normal dosing schedule. Never apply more gel to make up for a missed dose as this could lead to an overdose.

How quickly can I expect to see results?

Response times to topical gels can vary depending on many factors, including the severity of your condition. It is advisable to track your symptoms and communicate any changes - whether improvements or worsening of symptoms - to your healthcare provider.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Related Formulas

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Baclofen 1%/Cyclobenzaprine HCl 1%/Gabapentin 3%/Ketoprofen 10%/Lidocaine HCl 4% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)