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Formulas

Baclofen 2%/Cyclobenzaprine HCl 2%/Gabapentin 6%/Ketoprofen 20%/Lidocaine HCl 2.5% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Cyclobenzaprine Hydrochloride
Gabapentin
Ketoprofen
Lidocaine Hydrochloride
Baclofen

This formulation is a compounded topical gel containing Baclofen 2%, Cyclobenzaprine HCl 2%, Gabapentin 6%, Ketoprofen 20%, and Lidocaine HCl 2.5%. It is a semisolid formulation dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The combination of these active ingredients is designed to treat a variety of disease states. Baclofen is a muscle relaxant and antispastic agent, Cyclobenzaprine HCl is a muscle relaxant, Gabapentin is used to treat nerve pain and seizures, Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation, and Lidocaine HCl is a local anesthetic used to numb the skin and relieve pain.

Together, these ingredients work synergistically to provide relief from conditions such as neuropathic pain, muscle spasms, inflammation, and localized pain. This formulation is particularly beneficial for patients who require targeted, topical treatment for their symptoms.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Cyclobenzaprine Hydrochloride
Gabapentin
Ketoprofen
Lidocaine Hydrochloride
Baclofen
Topical Gel
6535c32a38489b504a447df6

Formula Information

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This formulation is a compounded topical gel containing Baclofen 2%, Cyclobenzaprine HCl 2%, Gabapentin 6%, Ketoprofen 20%, and Lidocaine HCl 2.5%. It is a semisolid formulation that is dispensed through a pump mechanism, allowing for easy and precise application on the skin. The gel-like consistency ensures that the active ingredients are absorbed directly into the targeted area, providing localized relief.

Baclofen is a muscle relaxant and antispastic agent that helps to relieve muscle spasms, tightness, and pain. Cyclobenzaprine HCl is another muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. Gabapentin is an anticonvulsant and nerve pain medication that is often used to treat nerve pain conditions. It works by calming down nerve activity, thereby reducing pain sensation.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. Lidocaine HCl is a local anesthetic that works by causing temporary numbness/loss of feeling in the skin and mucous membranes. This combination of medications in the formulation works synergistically to provide pain relief, reduce inflammation, and relax muscles in the targeted area.

This formulation can be used to treat a variety of disease states that involve pain, inflammation, and muscle spasms. These may include conditions like fibromyalgia, neuropathic pain, musculoskeletal pain, arthritis, and certain types of chronic pain conditions. It is important to note that this is a compounded medication, meaning it is made specifically for you based on a doctor's prescription. The strength and combination of ingredients can be adjusted to best meet your individual needs.

As with any medication, it is important to use this formulation as directed by your healthcare provider. Side effects may include skin irritation at the application site, dizziness, drowsiness, or dry mouth. If any of these effects persist or worsen, or if you experience any other side effects, contact your healthcare provider immediately.

If you have any questions about this formulation, how to use it, or if it is the right treatment for your condition, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to help.

Drug Interactions

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This topical gel formulation combines several active ingredients, each with its own potential for drug interactions. It's important to note that while this formulation is designed for topical use, systemic absorption can still occur, especially with prolonged use or application to large areas of skin. Therefore, drug interactions similar to those seen with oral administration of these medications can potentially occur.

Baclofen, a muscle relaxant and antispasmodic agent, may interact with other central nervous system (CNS) depressants like alcohol, benzodiazepines, opioids, and antihistamines, potentially leading to increased sedation and respiratory depression. It may also interact with antihypertensive drugs, potentially enhancing their effects and leading to hypotension.

Cyclobenzaprine, another muscle relaxant, also has potential interactions with CNS depressants, as well as with monoamine oxidase inhibitors (MAOIs), which can lead to a life-threatening condition called serotonin syndrome. It may also interact with drugs that affect the heart's rhythm, such as certain antibiotics and antipsychotics, potentially leading to arrhythmias.

Gabapentin, an anticonvulsant and nerve pain medication, may interact with antacids, reducing its absorption and effectiveness. It may also interact with opioids, potentially increasing the risk of severe respiratory depression. Additionally, it may interact with certain drugs for stomach acid, such as cimetidine, potentially increasing the levels of gabapentin in the body.

Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), may interact with other NSAIDs, increasing the risk of gastrointestinal bleeding. It may also interact with blood thinners, such as warfarin, potentially increasing the risk of bleeding. Additionally, it may interact with certain blood pressure medications, potentially reducing their effectiveness.

Lidocaine, a local anesthetic, may interact with other local anesthetics and certain heart medications, potentially leading to heart rhythm problems. It may also interact with certain seizure medications, potentially increasing the risk of side effects.

This formulation is primarily used to treat conditions like neuropathic pain, muscle spasms, and inflammation. The combination of these medications works synergistically to provide pain relief, muscle relaxation, and anti-inflammatory effects. However, it's important to use this medication as directed by your healthcare provider and to inform them of all the medications you're currently taking to avoid potential drug interactions.

If you have any questions about this formulation or its potential interactions, please don't hesitate to reach out to us.

How Does it Work

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This formulation is a combination of five active ingredients: Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. Each of these ingredients plays a unique role in the treatment of various disease states.

Baclofen is a muscle relaxant and antispasmodic agent that works by restoring the normal transmission of nerve signals in the central nervous system. It helps to relieve spasms, cramping, and tightness of muscles caused by certain medical conditions.

Cyclobenzaprine HCl is another muscle relaxant that works by blocking nerve impulses (or pain sensations) that are sent to your brain. It is used to treat muscle spasms caused by painful muscle conditions.

Gabapentin is an anticonvulsant and nerve pain medication. It works by calming down nerve activity to reduce pain signals. It is often used to treat nerve pain conditions, such as postherpetic neuralgia and diabetic neuropathy.

Ketoprofen is a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing hormones that cause inflammation and pain in the body. It is used to treat mild to moderate pain, or inflammation caused by arthritis.

Lidocaine HCl is a local anesthetic that works by blocking nerve signals in your body. It is used to relieve pain and discomfort caused by skin irritations, such as minor cuts, burns, and insect bites.

When applied topically, this formulation allows for targeted treatment, delivering the active ingredients directly to the area of discomfort. The gel-like consistency ensures easy and precise application, while the pump mechanism allows for controlled dispensing of the medication.

This formulation is often used to treat conditions such as muscle spasms, nerve pain, inflammation, and localized pain. By combining these five active ingredients, it offers a comprehensive approach to pain management, addressing not only the symptoms but also the underlying causes of pain.

If you have any questions about this formulation, or if you would like to know more about how it can be used to treat specific conditions, please don't hesitate to reach out to us. We are here to help.

Other Uses

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This compounded medication is primarily used for topical pain management, especially in cases where traditional oral medications have proven ineffective or resulted in unwanted side effects. Its unique combination of active ingredients enables it to tackle pain, inflammation, and muscle spasms in an innovative way, providing targeted relief for patients dealing with complex, hard-to-treat conditions.

Besides this, there may be several other potential uses for this medication. For instance, it might benefit people suffering from neuropathic pain – nerve damage often associated with diabetes, shingles, or spinal cord injuries. Baclofen, Gabapentin, and Cyclobenzaprine HCl are all medications that can address these types of nerve problems. Additionally, Ketoprofen could offer anti-inflammatory benefits, which would help in various conditions leading to swelling, redness, and pain.

Another potential application could be for musculoskeletal issues. The formulation contains multiple muscle relaxants which could potentially be beneficial in addressing conditions like fibromyalgia, myofascial pain syndrome, or even certain types of chronic low back pain, this version is believed to provide direct relief to the problem area. Besides, Lidocaine HCl present in the formula could provide rapid, short-term relief by numbing the area temporarily.

Despite these potential additional uses, it's important to note that the efficacy and safety of this medication for such uses may not have been extensively studied and always should be guided by the advice of your healthcare provider. The benefits of this therapy should always be weighed against any potential risks and used under the supervision of a health professional.

If you have any questions or need further information about this formulation, we encourage you to reach out to us. At Bayview Pharmacy, our knowledgeable team of compounding pharmacists is committed to understanding your specific therapeutic needs and providing the best possible solutions.

Frequently Asked Questions

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What is Baclofen 2%/Cyclobenzaprine HCl 2%/Gabapentin 6%/Ketoprofen 20%/Lidocaine HCl 2.5% Topical Gel?

This is a compounded medication that combines various active ingredients in precise proportions within a gel. It is designed to be applied directly to the skin for targeted treatment.

What does the pump mechanism on the bottle do?

The pump mechanism allows for easy and precise dispensing of the gel. It ensures the right amount of medication is used and reduces waste.

What is the consistency of the gel?

The gel has a semi-solid, gel-like consistency, which makes it easy to apply and absorb into the skin.

What are the active ingredients in the gel?

The gel is a combination of Baclofen, Cyclobenzaprine HCl, Gabapentin, Ketoprofen, and Lidocaine HCl. The respective percentages of each ingredient are as indicated.

Why are there so many active ingredients in the gel?

The combination of different substances enhances the therapeutic effect and can address multiple symptoms at once, which can be especially beneficial for certain medical conditions.

How should I apply the gel?

Apply the gel to the affected area as directed by your healthcare provider. The pump mechanism will help assure the correct dose.

Is this gel safe for all skin types?

While the gel is designed for most skin types, everyone's skin reacts differently to products. It is recommended to test a small amount first and to always follow the instructions of your healthcare professional.

How does the gel absorb into the skin?

The gel is designed to absorb quickly into your skin because of its formulation. However, the absorption rate can vary depending on individual skin types and conditions.

Can I use this topical gel with other medications?

It's important to discuss with your healthcare provider any other medications you're taking, as there could potentially be drug interactions, even with topical medications.

How often can I use this gel?

The frequency and duration of use will be determined by your healthcare provider based on your specific condition and needs.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Baclofen 2%/Cyclobenzaprine HCl 2%/Gabapentin 6%/Ketoprofen 20%/Lidocaine HCl 2.5% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)