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Ketamine HCl 10%/Gabapentin 6%/Amitriptyline HCl 5%/Baclofen 2%/Lidocaine 2% Topical Gel

This topical gel is a compounded formulation of Ketamine HCl 10%, Gabapentin 6%, Amitriptyline HCl 5%, Baclofen 2%, and Lidocaine 2%. It is dispensed through a pump mechanism for easy and precise application. The gel-like consistency allows for targeted treatment or absorption of active ingredients. It is used for the management of conditions such as Neuropathic Pain, Fibromyalgia, Migraine, Complex Regional Pain Syndrome, and Trigeminal Neuralgia.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NY, NJ, NH, FL and ME.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor

Licensed to fill prescriptions for patients in RI, MA, CT, NY, NJ, NH, FL and ME.

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Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Ketamine Hydrochloride
Gabapentin
Amitriptyline Hydrochloride
Baclofen
Lidocaine Hydrochloride
Topical Gel
6427079ea643245bbf518ccb

Formula Information

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This compounded formulation is a semisolid topical gel that contains five active ingredients: Ketamine HCl 10%, Gabapentin 6%, Amitriptyline HCl 5%, Baclofen 2%, and Lidocaine 2%. It is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The gel-like consistency ensures targeted treatment or absorption of the active ingredients.

The formulation is designed to treat a variety of conditions including neuropathic pain, fibromyalgia, migraine, trigeminal neuralgia, and complex regional pain syndrome. Each ingredient plays a crucial role in managing these conditions. Ketamine HCl is an NMDA receptor antagonist that has been shown to reduce pain and improve quality of life in patients with neuropathic pain. Gabapentin is an anticonvulsant that has been used to treat neuropathic pain, fibromyalgia, and migraine. Amitriptyline HCl is a tricyclic antidepressant that has been used to treat neuropathic pain, fibromyalgia, and migraine. Baclofen is a GABA agonist that has been used to treat neuropathic pain, fibromyalgia, and trigeminal neuralgia. Lidocaine is a local anesthetic that has been used to treat neuropathic pain, complex regional pain syndrome, and trigeminal neuralgia.

However, it should be used with caution in patients with a history of cardiovascular disease, as some of the active ingredients may increase the risk of arrhythmias. It is always recommended to consult with a healthcare provider before starting any new medication regimen.

If you have any questions about this formulation or how it can be used to treat neuropathic pain, fibromyalgia, migraine, trigeminal neuralgia, and complex regional pain syndrome, please do not hesitate to reach out. Our team of compounding pharmacists is here to provide the necessary information and guidance.

Drug Interactions

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This compounded formulation of Ketamine HCl 10%, Gabapentin 6%, Amitriptyline HCl 5%, Baclofen 2%, and Lidocaine 2% is a semisolid topical gel designed for easy and precise application on the skin. The gel-like consistency allows for targeted treatment or absorption of the active ingredients. This formulation has been studied for its potential use in the treatment of various conditions including Neuropathic Pain, Fibromyalgia, Migraine, Trigeminal Neuralgia, and Complex Regional Pain Syndrome.

The combination of these medications in the formulation is believed to provide analgesic and anti-inflammatory effects, as well as reduce the intensity of pain. Ketamine HCl, an NMDA receptor antagonist, Gabapentin, an anticonvulsant, and Amitriptyline HCl, a tricyclic antidepressant, have all been used in the treatment of neuropathic pain, fibromyalgia, and migraine. Baclofen, a GABA agonist, has been used to treat neuropathic pain, fibromyalgia, and trigeminal neuralgia. Lidocaine, a local anesthetic, has been used to treat neuropathic pain, complex regional pain syndrome, and trigeminal neuralgia.

It is important to note that this formulation has not been studied in combination with other medications and may interact with other medications. Therefore, patients should discuss any other medications they are taking with their healthcare provider before using this formulation. This is crucial to ensure the safety and effectiveness of the treatment.

How Does it Work

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This compounded formulation is a topical gel that combines five active ingredients: Ketamine HCl 10%, Gabapentin 6%, Amitriptyline HCl 5%, Baclofen 2%, and Lidocaine 2%. Each ingredient plays a crucial role in managing various chronic pain conditions. The gel is designed to provide targeted treatment by facilitating the absorption of these active ingredients through the skin.

Ketamine HCl works by blocking the transmission of pain signals to the brain, effectively reducing the sensation of pain. Gabapentin is known for its ability to reduce inflammation and nerve pain, making it particularly useful in conditions like neuropathic pain and fibromyalgia. Amitriptyline HCl, an antidepressant, contributes to pain reduction and improved sleep patterns. Baclofen is included for its ability to alleviate muscle spasms and pain. Lastly, Lidocaine serves as a local anesthetic, numbing the area of application to provide immediate pain relief.

The application of this topical gel should be done in accordance with the instructions provided by your healthcare provider. Typically, it should be applied to the affected area twice daily, or as directed. It's crucial to avoid contact with the eyes, nose, and mouth, and to wash your hands after application. The gel should not be used on broken or irritated skin.

It's important to understand that the full effect of this topical gel may take several weeks to manifest. Potential side effects may include skin irritation, itching, burning, or redness. If you experience any of these side effects, it's recommended to contact your healthcare provider immediately.

If you have any questions about this compounded formulation or how it can help manage your chronic pain condition, don't hesitate to reach out. We're here to provide the information and support you need.

Other Uses

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This compounded formulation of Ketamine HCl 10%, Gabapentin 6%, Amitriptyline HCl 5%, Baclofen 2%, and Lidocaine 2% is a topical gel designed for targeted treatment of various pain conditions. It is primarily indicated for the management of Neuropathic Pain, Fibromyalgia, Migraine, Complex Regional Pain Syndrome, and Trigeminal Neuralgia. Additionally, it has been utilized off-label for the treatment of other chronic pain conditions, including chronic low back pain, chronic neck pain, and chronic headaches.

The gel is dispensed through a pump mechanism, which allows for easy and precise application directly to the affected area. The active ingredients are then absorbed through the skin, providing targeted relief.

It is crucial to remember that this topical gel should not be applied to broken or irritated skin. If you have any questions or concerns about the use of this formulation, it is recommended to consult with a healthcare professional. This formulation is a testament to the advancements in pain management, offering a non-invasive, targeted approach to chronic pain relief.

Frequently Asked Questions

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What is this compounded formulation of Ketamine HCl 10%/Gabapentin 6%/Amitriptyline HCl 5%/Baclofen 2%/Lidocaine 2% Topical Gel?

This is a compounded medication that combines several active ingredients into a single topical gel. It is designed to be applied directly to the skin for targeted treatment.

How is this medication dispensed?

This medication is dispensed through a pump mechanism, which allows for easy and precise application on the skin.

What is the consistency of this medication?

This medication has a gel-like consistency, which makes it easy to apply and absorb into the skin.

What are the active ingredients in this medication?

The active ingredients in this medication are Ketamine HCl, Gabapentin, Amitriptyline HCl, Baclofen, and Lidocaine.

What is the purpose of each active ingredient in this medication?

Each active ingredient in this medication serves a specific purpose. Ketamine HCl is used for pain relief, Gabapentin is used to treat nerve pain, Amitriptyline HCl is used to help relieve certain types of nerve pain, Baclofen is used to treat muscle spasms, and Lidocaine is used as a local anesthetic.

How should this medication be stored?

This medication should be stored at room temperature, away from heat and direct light. Do not freeze.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not apply extra doses.

What are the potential side effects of this medication?

Some potential side effects of this medication may include skin irritation, redness, or a burning sensation at the application site. If these symptoms persist or worsen, contact your healthcare provider.

Can I use this medication if I am pregnant or breastfeeding?

Before using this medication, tell your healthcare provider if you are pregnant or breastfeeding. The effects of this medication on unborn babies and nursing infants are not fully known.

Can I use other medications while using this topical gel?

Before starting any new medication, including over-the-counter drugs and supplements, you should discuss it with your healthcare provider. Some medications may interact with the active ingredients in this topical gel.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NY, NJ, NH, FL, and ME. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Ketamine HCl 10%/Gabapentin 6%/Amitriptyline HCl 5%/Baclofen 2%/Lidocaine 2% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)