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Ketamine HCl 10%/Gabapentin 6%/Amitriptyline HCl 5%/Baclofen 2% Topical Gel

FDA-approved generic
Dose form
Topical Gel
Active ingredients
Ketamine Hydrochloride
Gabapentin
Amitriptyline Hydrochloride
Baclofen

Bayview Pharmacy's compounded formulation of Ketamine HCl 10%/Gabapentin 6%/Amitriptyline HCl 5%/Baclofen 2% Topical Gel is a semisolid medication dispensed through a pump mechanism. This allows for easy and precise application on the skin, facilitating targeted treatment or absorption of active ingredients. The gel-like consistency is designed to treat conditions such as neuropathic pain, fibromyalgia, migraine, trigeminal neuralgia, and complex regional pain syndrome.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Get a one-page sheet with everything your doctor needs to prescribe this and send it to Bayview.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Ketamine Hydrochloride
Gabapentin
Amitriptyline Hydrochloride
Baclofen
Topical Gel
6427079ea64324f98f518cc9
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Currently licensed Limited basis, registration pending Not available for this formula Not currently licensed

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Formula Information

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Bayview Pharmacy's compounded formulation of Ketamine HCl 10%/Gabapentin 6%/Amitriptyline HCl 5%/Baclofen 2% Topical Gel is a specialized blend designed to address a range of chronic pain conditions. This unique formulation is specifically tailored to manage neuropathic pain, fibromyalgia, migraines, trigeminal neuralgia, and complex regional pain syndrome.

The combination of ketamine, gabapentin, amitriptyline, and baclofen in this topical gel creates a synergistic effect that aids in reducing pain and inflammation. Ketamine, an NMDA receptor antagonist, and amitriptyline, a tricyclic antidepressant, both contribute to the reduction of pain and inflammation. Gabapentin, an anticonvulsant, specifically targets neuropathic pain, while baclofen, a muscle relaxant, helps to alleviate muscle spasms and pain. This blend of medications not only reduces pain and inflammation but also provides a calming effect.

This semisolid formulation is dispensed through a pump mechanism, facilitating easy and precise application on the skin for targeted treatment or absorption of active ingredients in a gel-like consistency. The topical gel is easy to apply and can be used as needed for pain relief. However, it is crucial to remember that this formulation should not replace other medications prescribed by a healthcare provider. Always consult with your healthcare provider before using this formulation.

If you have any questions about this compounded formulation of Ketamine HCl 10%/Gabapentin 6%/Amitriptyline HCl 5%/Baclofen 2% Topical Gel or how it can help manage neuropathic pain, fibromyalgia, migraines, trigeminal neuralgia, or complex regional pain syndrome, please reach out to us at Bayview Pharmacy.

Drug Interactions

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This compounded formulation of Ketamine HCl 10%, Gabapentin 6%, Amitriptyline HCl 5%, and Baclofen 2% in a topical gel form is a targeted treatment for a variety of chronic pain conditions. The gel is dispensed through a pump mechanism, allowing for easy and precise application on the skin.

Ketamine HCl, an NMDA receptor antagonist, has demonstrated efficacy in reducing neuropathic pain.

This topical gel formulation can be used as an adjunct to other treatments, such as physical therapy, to help reduce pain and improve quality of life. It is important to note that the effectiveness of this formulation can vary depending on the individual and the specific condition being treated. Therefore, it is recommended to consult with a healthcare provider to determine the most appropriate treatment plan. If you have any questions about this formulation or its potential uses, please do not hesitate to reach out.

How Does it Work

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This compounded formulation is a topical gel that combines four potent medications: Ketamine HCl 10%, Gabapentin 6%, Amitriptyline HCl 5%, and Baclofen 2%. Each of these medications plays a unique role in managing pain and inflammation. Ketamine, an anesthetic, functions by blocking nerve signals in the brain. Gabapentin, an anticonvulsant, works by reducing abnormal nerve activity. Amitriptyline, a tricyclic antidepressant, increases the levels of serotonin and norepinephrine in the brain. Lastly, Baclofen, a muscle relaxant, helps in decreasing muscle spasms. The synergistic effect of these medications aids in reducing pain and inflammation in the targeted area.

This topical gel is indicated for a range of chronic pain conditions. It can be used to manage neuropathic pain, a condition caused by nerve damage, by reducing associated pain and inflammation. It is also beneficial for fibromyalgia patients, a chronic pain condition causing widespread pain and fatigue, by alleviating pain and enhancing overall quality of life. For migraine sufferers, who experience intense headaches often accompanied by nausea and sensitivity to light and sound, this gel can help lessen the severity of the pain. Lastly, it can be used to manage complex regional pain syndrome, a chronic pain condition caused by nerve damage, by reducing the associated pain and inflammation.

The topical gel should be applied directly to the affected area as per the instructions of your healthcare provider. The dosage and frequency of application may vary depending on the severity of your condition. It is crucial to adhere to the instructions provided by your healthcare provider. If you have any queries about the usage of this topical gel, it is recommended to consult with your healthcare provider.

Other Uses

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This compounded formulation of Ketamine HCl 10%, Gabapentin 6%, Amitriptyline HCl 5%, and Baclofen 2% in a topical gel form is designed for targeted treatment of various pain conditions. It is primarily indicated for the management of Neuropathic Pain, Fibromyalgia, Migraine, Trigeminal Neuralgia, and Complex Regional Pain Syndrome. Additionally, it has shown efficacy in treating other conditions such as chronic musculoskeletal pain, post-herpetic neuralgia, and diabetic neuropathy.

The gel is dispensed through a pump mechanism, which allows for easy and precise application on the skin. The active ingredients are absorbed through the skin, directly targeting the affected area. This method of application bypasses the systemic circulation, potentially reducing the risk of systemic side effects.

It is crucial to note that this formulation should not be applied to open wounds or broken skin. Some patients may experience skin irritation, including signs of redness, itching, or burning. If these symptoms occur, discontinue use and consult a healthcare professional. Furthermore, this formulation should not be used concurrently with other topical medications or products, as this may alter the absorption and effectiveness of the active ingredients.

As with all medications, it is important to use this product as directed by a healthcare professional. If you have any questions or concerns about this formulation, please consult your healthcare provider or pharmacist.

Frequently Asked Questions

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What is the Ketamine HCl 10%/Gabapentin 6%/Amitriptyline HCl 5%/Baclofen 2% Topical Gel?

This is a compounded formulation of four active ingredients: Ketamine HCl, Gabapentin, Amitriptyline HCl, and Baclofen. It is a semisolid formulation that is dispensed through a pump mechanism for easy and precise application on the skin.

What is the purpose of this compounded formulation?

This formulation is designed for targeted treatment or absorption of the active ingredients. It is typically used for pain management and muscle relaxation.

How should I apply this topical gel?

This gel should be applied directly to the skin in the area where treatment is needed. The pump mechanism allows for easy and precise application.

What is the consistency of this topical gel?

The gel has a semisolid, gel-like consistency which allows it to be easily spread on the skin for targeted treatment.

Can this gel be used on all skin types?

Generally, this gel can be used on all skin types. However, if you have sensitive skin or known allergies, it is recommended to consult with your healthcare provider before use.

What are the active ingredients in this formulation?

The active ingredients in this formulation are Ketamine HCl, Gabapentin, Amitriptyline HCl, and Baclofen.

What are the potential side effects of this topical gel?

As with any medication, side effects can occur. These may include skin irritation, redness, or an allergic reaction. If you experience any unusual symptoms, discontinue use and consult your healthcare provider.

How should I store this topical gel?

This gel should be stored at room temperature, away from heat and direct sunlight. Keep the container tightly closed when not in use.

Can I use this gel with other medications?

Before using this gel with other medications, it is recommended to consult with your healthcare provider to avoid potential interactions.

What should I do if I miss a dose?

If you miss a dose, apply it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

The conditions listed on this page are indications prescribers have ordered this preparation for. They are not FDA-approved indications, and listing them is not a statement that this preparation is effective for them.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

This preparation is a controlled substance. Additional prescribing, refill, and shipping restrictions apply, and the states Bayview can dispense it to are narrower than for non-controlled preparations.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Ketamine HCl 10%/Gabapentin 6%/Amitriptyline HCl 5%/Baclofen 2% Topical Gel
Topical Gel
60 g
controlled

Apply topically to affected area(s)

Three times daily