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Active pharmaceutical ingredient

Clindamycin Phosphate

Clindamycin Phosphate is a lincosamide antibiotic that Bayview compounds to a prescriber's order.

Compounded to order
Prescription required

About this ingredient

Clindamycin phosphate is an antibiotic belonging to the lincosamide class. It works by binding to the 50S ribosomal subunit and inhibiting bacterial protein synthesis, thereby slowing or stopping the growth of susceptible bacteria.[1][3] Clindamycin is active against many gram-positive cocci and anaerobic bacteria, and it is used in skin and soft tissue infections.[1]

In dermatology, clindamycin phosphate is used in topical products such as solutions, gels, lotions, and foams to treat acne vulgaris.[3][4] Clindamycin is active in vitro against most isolates of Propionibacterium acnes, although the FDA label notes that the clinical significance of this, and the mechanism of action in acne, are unknown.[4] MedlinePlus describes topical clindamycin as working by slowing or stopping the growth of bacteria that cause acne and by decreasing swelling.[3] Clindamycin phosphate is also the salt form used in injectable clindamycin.[1]

Systemically administered clindamycin is widely distributed in body fluids and tissues, including bone, while topical application produces very low serum levels.[2][4] Diarrhea, bloody diarrhea, and colitis, including pseudomembranous colitis, have been reported with both topical and systemic clindamycin.[4] Healthcare providers should consider the patient's medical history and the potential for antibiotic resistance when prescribing clindamycin phosphate. Bayview compounds clindamycin phosphate on a prescriber's order.

Compounded at Bayview

How we prepare this ingredient

Patient guides for the preparations we make most often. Each one is compounded to order and requires a prescription.

For prescribers

Full formulary with this ingredient

Every preparation in our formulary that contains this ingredient. Strength, base and dose form are set by the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.