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Active pharmaceutical ingredient

Aminolevulinic Acid Hydrochloride

Aminolevulinic Acid Hydrochloride is a versatile active pharmaceutical ingredient commonly utilized in dermatological and oncological treatments.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Aminolevulinic Acid Hydrochloride is a pivotal active pharmaceutical ingredient utilized in various compounded formulations, primarily for its role in photodynamic therapy. This compound is a prodrug that, upon topical application, is metabolized into protoporphyrin IX, a photosensitizer that accumulates in abnormal cells. When exposed to specific wavelengths of light, it generates reactive oxygen species, leading to targeted cytotoxic effects on dysplastic or neoplastic cells.

Clinically, Aminolevulinic Acid Hydrochloride is employed in the treatment of actinic keratosis, superficial basal cell carcinoma, and other dermatological conditions where selective phototoxicity is beneficial. Its mechanism of action allows for precision in targeting abnormal cells while sparing surrounding healthy tissue, making it a valuable tool in dermatological oncology. The efficacy of this API is enhanced by its ability to penetrate the stratum corneum and localize within the epidermis, ensuring optimal therapeutic outcomes.

Prescribers should be aware of the photosensitivity associated with Aminolevulinic Acid Hydrochloride, necessitating patient education on light exposure post-application. The compound's pharmacokinetics and safety profile are well-documented, with a favorable balance between therapeutic benefits and manageable side effects. As a versatile component in compounded formulations, it offers customizable treatment options tailored to individual patient needs, enhancing the scope of personalized medicine in dermatology.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.