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Active pharmaceutical ingredient

Clobazam Hydrochloride

Clobazam Hydrochloride is a benzodiazepine derivative primarily used for its anticonvulsant and anxiolytic properties.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Clobazam Hydrochloride is a benzodiazepine derivative primarily used for its anticonvulsant properties, making it a valuable component in the management of seizure disorders. It functions by enhancing the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, which results in a calming effect on the brain and nervous system. This mechanism of action is particularly beneficial in reducing the frequency and severity of seizures, especially in conditions like Lennox-Gastaut syndrome.

In addition to its anticonvulsant effects, Clobazam Hydrochloride also exhibits anxiolytic properties, which can be advantageous in patients who experience anxiety as a comorbid condition with epilepsy. The pharmacokinetics of Clobazam Hydrochloride involve its metabolism in the liver, primarily through the cytochrome P450 enzyme system, which can lead to interactions with other medications metabolized by the same pathway. Therefore, careful consideration and monitoring are essential when prescribing this medication, especially in polypharmacy scenarios.

Clobazam Hydrochloride is generally well-tolerated, but like all benzodiazepines, it carries a risk of dependence and withdrawal symptoms if used long-term. Common side effects may include drowsiness, dizziness, and fatigue, which should be communicated to patients to ensure adherence and safety. Its use in compounded formulations allows for tailored dosing and delivery methods, enhancing patient-specific treatment plans and improving therapeutic outcomes.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.