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Active pharmaceutical ingredient

Loperamide Hydrochloride

Loperamide Hydrochloride is a potent antidiarrheal agent commonly utilized in compounded formulations to manage symptoms of acute and chronic diarrhea.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Loperamide Hydrochloride is a synthetic opioid receptor agonist primarily used to manage and treat diarrhea by slowing down gut movement. It acts on the mu-opioid receptors in the gastrointestinal tract, reducing peristalsis and increasing the transit time of intestinal contents, which allows for greater absorption of fluids and electrolytes.

This mechanism of action makes Loperamide Hydrochloride an effective agent in reducing the frequency of bowel movements and improving stool consistency. It is particularly beneficial in cases of acute nonspecific diarrhea and chronic diarrhea associated with inflammatory bowel disease or irritable bowel syndrome.

While Loperamide Hydrochloride is generally well-tolerated, it is important for prescribers to be aware of potential side effects, such as constipation, dizziness, and, in rare cases, more severe cardiac events when used in high doses. It is crucial to adhere to recommended dosages and consider patient-specific factors, such as existing medical conditions and concurrent medications, to minimize risks.

In the context of compounding, Loperamide Hydrochloride can be formulated into various dosage forms to meet the specific needs of patients who may require tailored therapy. This flexibility allows healthcare providers to optimize treatment regimens, ensuring effective symptom management while enhancing patient compliance and comfort.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.