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Active pharmaceutical ingredient

Medroxyprogesterone Acetate

Medroxyprogesterone Acetate is a synthetic progestin commonly used in hormone replacement therapy and various gynecological treatments.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Medroxyprogesterone Acetate is a synthetic progestin, a derivative of progesterone, widely used in various therapeutic applications. It plays a crucial role in hormone replacement therapy, particularly for managing symptoms associated with menopause, such as hot flashes and osteoporosis prevention. Its efficacy in regulating menstrual cycles and treating amenorrhea and abnormal uterine bleeding is well-documented, making it a valuable component in gynecological treatments.

In addition to its gynecological uses, Medroxyprogesterone Acetate is also employed in oncology for its antineoplastic properties, particularly in the treatment of endometrial and renal cancers. Its mechanism of action involves binding to progesterone receptors, which modulates gene expression and inhibits the growth of hormone-sensitive tumors. This API is also utilized in contraceptive formulations, providing long-term birth control through its ability to suppress ovulation.

Medroxyprogesterone Acetate is known for its favorable pharmacokinetic profile, with a long half-life that supports sustained therapeutic effects. It is metabolized primarily in the liver and excreted via the kidneys, necessitating careful consideration in patients with hepatic or renal impairment. The safety and efficacy of Medroxyprogesterone Acetate have been established through extensive clinical trials, although it is important for prescribers to monitor for potential side effects, such as weight gain, mood changes, and thromboembolic events.

When considering Medroxyprogesterone Acetate for compounded formulations, it is essential to tailor the dosage and delivery method to the individual patient's needs, ensuring optimal therapeutic outcomes. Its versatility and effectiveness make it a staple in personalized medicine, offering solutions for a range of hormonal and oncological conditions. As with any medication, a thorough understanding of the patient's medical history and concurrent medications is vital to minimize interactions and maximize benefits.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.