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Active pharmaceutical ingredient

Poloxamer

Poloxamer is a versatile nonionic triblock copolymer widely utilized in pharmaceutical formulations for its unique thermoreversible gelation properties.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Poloxamer is a versatile nonionic triblock copolymer widely utilized in pharmaceutical compounding due to its unique thermoreversible gelation properties. This characteristic allows poloxamer to transition from a liquid at low temperatures to a gel at body temperature, making it an ideal excipient for topical, ophthalmic, and injectable formulations. Its ability to enhance the solubility and stability of active pharmaceutical ingredients (APIs) further underscores its importance in compounding applications.

In addition to its solubilizing capabilities, poloxamer acts as an effective emulsifying and stabilizing agent, which is crucial for maintaining the homogeneity and efficacy of compounded formulations. Its biocompatibility and low toxicity profile make it suitable for a wide range of therapeutic applications, including those requiring sustained or controlled drug release. Poloxamer's role in enhancing the bioavailability of poorly soluble drugs is particularly beneficial in optimizing therapeutic outcomes.

Moreover, poloxamer's surfactant properties facilitate the dispersion of hydrophobic compounds, improving the delivery and absorption of active ingredients. This makes it a valuable component in formulations designed for mucosal delivery, where rapid and efficient drug absorption is desired. Its use in compounding extends to veterinary medicine as well, where it aids in the formulation of palatable and effective treatments for animals.

Overall, poloxamer's multifunctional properties and adaptability in various pharmaceutical formulations make it an indispensable ingredient in the compounding pharmacy sector. Its ability to improve drug solubility, stability, and delivery ensures that compounded medications meet the specific needs of patients, providing tailored therapeutic solutions. As a result, poloxamer continues to be a critical component in the development of innovative and effective compounded medications.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.