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Active pharmaceutical ingredient

Tramadol Hydrochloride

Tramadol Hydrochloride is a centrally acting synthetic opioid analgesic used in the management of moderate to moderately severe pain.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Tramadol Hydrochloride is a centrally acting synthetic opioid analgesic used in the management of moderate to moderately severe pain. It functions by binding to the mu-opioid receptors in the brain, altering the perception and response to pain, while also inhibiting the reuptake of norepinephrine and serotonin, contributing to its analgesic effects.

Due to its dual mechanism of action, Tramadol Hydrochloride is often considered for patients who require a step up from non-opioid analgesics but may not yet need stronger opioids. It is metabolized in the liver primarily by the CYP2D6 enzyme, and its efficacy can be influenced by genetic variations in this enzyme, affecting the conversion to its active metabolite, O-desmethyltramadol.

Tramadol Hydrochloride is available in various formulations, allowing for flexible dosing tailored to individual patient needs. It is important for prescribers to consider the potential for abuse and dependence, as well as the risk of serotonin syndrome, especially when used in combination with other serotonergic drugs.

When prescribing Tramadol Hydrochloride, careful assessment of the patient's pain management needs, history of substance use, and potential drug interactions is crucial. Monitoring for adverse effects such as dizziness, nausea, constipation, and CNS depression is essential to ensure safe and effective use.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

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Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.