Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo is a liquid formulation designed for cleansing and conditioning the hair and scalp. It is typically used during bathing or showering, providing a lathering and rinsing action to effectively remove dirt, oil, and impurities. This shampoo is specifically formulated to treat inflammatory scalp conditions such as psoriasis and seborrheic dermatitis, promoting healthy hair and scalp conditions.

Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
This medicated shampoo combines Clobetasol Propionate 0.5 mg/mL and Pyrithione Zinc 2 mg/mL in a liquid formulation designed for cleansing and conditioning the hair and scalp. Used during bathing or showering, it provides a lathering and rinsing action to remove dirt, oil, and impurities while promoting healthy hair and scalp conditions.
Clobetasol Propionate is a potent topical corticosteroid that works by reducing inflammation, itching, and redness associated with various scalp conditions. It inhibits the release of inflammatory mediators, effectively alleviating symptoms of conditions such as psoriasis, eczema, and dermatitis affecting the scalp.
Pyrithione Zinc is an antifungal and antibacterial agent that helps control and reduce the symptoms of dandruff and seborrheic dermatitis. It works by inhibiting the growth of yeast and bacteria on the scalp, thereby reducing flaking, scaling, and irritation.
The combination of Clobetasol Propionate and Pyrithione Zinc in this shampoo provides a synergistic effect, targeting both the inflammatory and microbial components of scalp conditions. This dual-action approach offers comprehensive relief from symptoms, promoting healthier scalp and hair.
This formulation is commonly prescribed for the treatment of inflammatory scalp conditions such as psoriasis, seborrheic dermatitis, and severe dandruff. It is especially useful in cases where symptoms are resistant to standard therapies, providing a more potent treatment option.
Patients should apply the shampoo to wet hair and scalp, massaging gently to create a rich lather. Allow the shampoo to remain on the scalp for a few minutes to maximize therapeutic effects before rinsing thoroughly. The frequency of use should be as directed by the prescribing healthcare
Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo is a topical formulation designed to treat inflammatory and pruritic manifestations of moderate to severe scalp psoriasis and seborrheic dermatitis. Clobetasol propionate is a potent corticosteroid that helps reduce inflammation, redness, and itching, while pyrithione zinc is an antifungal and antibacterial agent that helps control the growth of yeast and bacteria on the scalp, contributing to the reduction of flaking and scaling.
When using this shampoo, it is important to consider potential drug interactions, especially for patients who are on other medications. Although the systemic absorption of clobetasol propionate from topical application is generally low, it can still occur, particularly with prolonged use or when applied to large surface areas. This can potentially lead to interactions with other corticosteroids or medications that affect the hypothalamic-pituitary-adrenal (HPA) axis, such as ritonavir or itraconazole, which may increase the risk of systemic corticosteroid effects.
Patients using other topical medications on the scalp should consult with their healthcare provider to ensure compatibility, as concurrent use may alter the absorption or efficacy of either product. Additionally, patients on immunosuppressive therapies should be monitored closely, as the immunosuppressive effects of corticosteroids could be potentiated, increasing the risk of infections.
For prescribers, it is crucial to evaluate the patient's complete medication profile, including over-the-counter products and supplements, to identify any potential interactions. Monitoring for signs of HPA axis suppression, such as fatigue, weakness, or hypotension, is recommended, especially in patients using the shampoo over extended periods or in conjunction with other corticosteroid-containing products.
Patients should be advised to use the shampoo as directed, typically applying it to the affected areas of the scalp, lathering, and rinsing thoroughly. They should be informed about the importance of not using the product more frequently than prescribed to minimize the risk of systemic absorption and potential interactions.
If you have any questions or concerns about using Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo, or if you need further information on potential drug interactions, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.
This liquid formulation combines Clobetasol Propionate and Pyrithione Zinc in a shampoo base, designed to cleanse and condition the hair and scalp effectively. Clobetasol Propionate is a potent topical corticosteroid that works by reducing inflammation, itching, and redness associated with various scalp conditions. It achieves this by inhibiting the release of inflammatory mediators and suppressing the immune response in the affected area. This action helps alleviate symptoms of inflammatory scalp disorders such as psoriasis and seborrheic dermatitis, providing relief from discomfort and irritation.
Pyrithione Zinc, on the other hand, is an antifungal and antibacterial agent that helps control the growth of yeast and bacteria on the scalp. By reducing the proliferation of these microorganisms, Pyrithione Zinc helps to decrease flaking, scaling, and itching, promoting a healthier scalp environment.
When used as a shampoo, this formulation not only targets the underlying causes of scalp conditions but also provides a cleansing action that removes dirt, oil, and impurities from the hair and scalp. The lathering action ensures that the active ingredients are evenly distributed across the scalp, maximizing their therapeutic effects. The conditioning properties of the shampoo help to maintain the hair's moisture balance, leaving it soft and manageable after rinsing.
It is important to follow the prescribed usage instructions to achieve optimal results. For prescribers, this combination of Clobetasol Propionate and Pyrithione Zinc in a shampoo form provides a dual-action approach to treating inflammatory and microbial components of scalp disorders, making it a versatile option for patients with complex scalp issues.
If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries you may have.
This shampoo is used for cleansing and conditioning the hair and scalp, while also treating inflammatory scalp conditions such as psoriasis and seborrheic dermatitis. It helps to reduce itching, redness, and flaking.
Apply the shampoo to wet hair and scalp, lather, and leave it on for a few minutes before rinsing thoroughly. Follow your healthcare provider's instructions regarding the frequency of use.
While this shampoo is generally safe for use on colored or treated hair, it is advisable to consult with your healthcare provider or a hair care professional to ensure it is suitable for your specific hair type and treatment.
Some users may experience mild side effects such as skin irritation, dryness, or a burning sensation. If you experience severe side effects or an allergic reaction, discontinue use and consult your healthcare provider.
Results can vary depending on the individual and the condition being treated. Some users may notice improvements within a few weeks, while others may require longer use. Consistent use as directed is important for optimal results.
It is important to follow your healthcare provider's instructions regarding the frequency of use. Overuse may lead to increased side effects or reduced effectiveness.
The safety and effectiveness of this shampoo in children have not been established. Consult a healthcare provider before using it on children.
Yes, you can use other hair care products, but it is advisable to avoid products that may irritate the scalp or interfere with the effectiveness of the shampoo. Consult your healthcare provider for specific recommendations.
If you miss a dose, use the shampoo as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.
Store the shampoo at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.
This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.
A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.
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Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.
Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.
Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.
Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.
Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.
Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.
Apply topically to affected area(s)