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Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo

FDA-approved generic
Dose form
Shampoo
Active ingredients
Clobetasol Propionate
Pyrithione Zinc

Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo is a liquid formulation designed for cleansing and conditioning the hair and scalp. It is typically used during bathing or showering, providing a lathering and rinsing action to effectively remove dirt, oil, and impurities. This shampoo is specifically formulated to treat inflammatory scalp conditions such as psoriasis and seborrheic dermatitis, promoting healthy hair and scalp conditions.

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For prescribers
Prescription details
RxThis formula
Dose formSee below
Quantity____
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription detailsOrder form
Controlled substance: e-prescribe (EPCS) from your EHR. Faxed and phoned prescriptions cannot be accepted for this preparation.
Send it from your EHR, or fax to (401) 284-4506. How to e-prescribe this formula
Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
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This medication requires a prescription from your doctor
Ships within 1 to 2 business days after pharmacist verification
HSA and FSA eligible
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Licensed to fill prescriptions for patients in RI, MA, CT, NJ, NH, FL, ME and PA. New York patients are served on a limited basis while nonresident registration is pending.

For prescribersSign in for prescription details and order forms.
Compounded preparations are prepared by Bayview pursuant to a prescription for an individual patient. They are not FDA-approved and have not been evaluated by FDA for safety or effectiveness.
Clobetasol Propionate
Pyrithione Zinc
Shampoo
Service area

Can we ship this formula to your state?

Bayview fills prescriptions for patients in Connecticut, Florida, Maine, Massachusetts, New Hampshire, New Jersey, Pennsylvania and Rhode Island. New York patients are served on a limited basis while nonresident pharmacy registration is pending.

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Formula Information

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This medicated shampoo combines Clobetasol Propionate 0.5 mg/mL and Pyrithione Zinc 2 mg/mL in a liquid formulation designed for cleansing and conditioning the hair and scalp. Used during bathing or showering, it provides a lathering and rinsing action to remove dirt, oil, and impurities while promoting healthy hair and scalp conditions.

Clobetasol Propionate is a potent topical corticosteroid that works by reducing inflammation, itching, and redness associated with various scalp conditions. It inhibits the release of inflammatory mediators, effectively alleviating symptoms of conditions such as psoriasis, eczema, and dermatitis affecting the scalp.

Pyrithione Zinc is an antifungal and antibacterial agent that helps control and reduce the symptoms of dandruff and seborrheic dermatitis. It works by inhibiting the growth of yeast and bacteria on the scalp, thereby reducing flaking, scaling, and irritation.

The combination of Clobetasol Propionate and Pyrithione Zinc in this shampoo provides a synergistic effect, targeting both the inflammatory and microbial components of scalp conditions. This dual-action approach offers comprehensive relief from symptoms, promoting healthier scalp and hair.

This formulation is commonly prescribed for the treatment of inflammatory scalp conditions such as psoriasis, seborrheic dermatitis, and severe dandruff. It is especially useful in cases where symptoms are resistant to standard therapies, providing a more potent treatment option.

Patients should apply the shampoo to wet hair and scalp, massaging gently to create a rich lather. Allow the shampoo to remain on the scalp for a few minutes to maximize therapeutic effects before rinsing thoroughly. The frequency of use should be as directed by the prescribing healthcare

Drug Interactions

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Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo is a topical formulation designed to treat inflammatory and pruritic manifestations of moderate to severe scalp psoriasis and seborrheic dermatitis. Clobetasol propionate is a potent corticosteroid that helps reduce inflammation, redness, and itching, while pyrithione zinc is an antifungal and antibacterial agent that helps control the growth of yeast and bacteria on the scalp, contributing to the reduction of flaking and scaling.

When using this shampoo, it is important to consider potential drug interactions, especially for patients who are on other medications. Although the systemic absorption of clobetasol propionate from topical application is generally low, it can still occur, particularly with prolonged use or when applied to large surface areas. This can potentially lead to interactions with other corticosteroids or medications that affect the hypothalamic-pituitary-adrenal (HPA) axis, such as ritonavir or itraconazole, which may increase the risk of systemic corticosteroid effects.

Patients using other topical medications on the scalp should consult with their healthcare provider to ensure compatibility, as concurrent use may alter the absorption or efficacy of either product. Additionally, patients on immunosuppressive therapies should be monitored closely, as the immunosuppressive effects of corticosteroids could be potentiated, increasing the risk of infections.

For prescribers, it is crucial to evaluate the patient's complete medication profile, including over-the-counter products and supplements, to identify any potential interactions. Monitoring for signs of HPA axis suppression, such as fatigue, weakness, or hypotension, is recommended, especially in patients using the shampoo over extended periods or in conjunction with other corticosteroid-containing products.

Patients should be advised to use the shampoo as directed, typically applying it to the affected areas of the scalp, lathering, and rinsing thoroughly. They should be informed about the importance of not using the product more frequently than prescribed to minimize the risk of systemic absorption and potential interactions.

If you have any questions or concerns about using Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo, or if you need further information on potential drug interactions, please reach out to us at Bayview Pharmacy. Our team of knowledgeable compounding pharmacists is here to assist you.

How Does it Work

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This liquid formulation combines Clobetasol Propionate and Pyrithione Zinc in a shampoo base, designed to cleanse and condition the hair and scalp effectively. Clobetasol Propionate is a potent topical corticosteroid that works by reducing inflammation, itching, and redness associated with various scalp conditions. It achieves this by inhibiting the release of inflammatory mediators and suppressing the immune response in the affected area. This action helps alleviate symptoms of inflammatory scalp disorders such as psoriasis and seborrheic dermatitis, providing relief from discomfort and irritation.

Pyrithione Zinc, on the other hand, is an antifungal and antibacterial agent that helps control the growth of yeast and bacteria on the scalp. By reducing the proliferation of these microorganisms, Pyrithione Zinc helps to decrease flaking, scaling, and itching, promoting a healthier scalp environment.

When used as a shampoo, this formulation not only targets the underlying causes of scalp conditions but also provides a cleansing action that removes dirt, oil, and impurities from the hair and scalp. The lathering action ensures that the active ingredients are evenly distributed across the scalp, maximizing their therapeutic effects. The conditioning properties of the shampoo help to maintain the hair's moisture balance, leaving it soft and manageable after rinsing.

It is important to follow the prescribed usage instructions to achieve optimal results. For prescribers, this combination of Clobetasol Propionate and Pyrithione Zinc in a shampoo form provides a dual-action approach to treating inflammatory and microbial components of scalp disorders, making it a versatile option for patients with complex scalp issues.

If you have any questions or need further information about this formulation, please reach out to us at Bayview Pharmacy. Our team of compounding pharmacists is here to assist you with any inquiries you may have.

Frequently Asked Questions

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What is Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo used for?

This shampoo is used for cleansing and conditioning the hair and scalp, while also treating inflammatory scalp conditions such as psoriasis and seborrheic dermatitis. It helps to reduce itching, redness, and flaking.

How should I use Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo?

Apply the shampoo to wet hair and scalp, lather, and leave it on for a few minutes before rinsing thoroughly. Follow your healthcare provider's instructions regarding the frequency of use.

Can I use this shampoo on colored or treated hair?

While this shampoo is generally safe for use on colored or treated hair, it is advisable to consult with your healthcare provider or a hair care professional to ensure it is suitable for your specific hair type and treatment.

Are there any side effects associated with this shampoo?

Some users may experience mild side effects such as skin irritation, dryness, or a burning sensation. If you experience severe side effects or an allergic reaction, discontinue use and consult your healthcare provider.

How long does it take to see results with this shampoo?

Results can vary depending on the individual and the condition being treated. Some users may notice improvements within a few weeks, while others may require longer use. Consistent use as directed is important for optimal results.

Can I use this shampoo every day?

It is important to follow your healthcare provider's instructions regarding the frequency of use. Overuse may lead to increased side effects or reduced effectiveness.

Is this shampoo safe for children?

The safety and effectiveness of this shampoo in children have not been established. Consult a healthcare provider before using it on children.

Can I use other hair care products while using this shampoo?

Yes, you can use other hair care products, but it is advisable to avoid products that may irritate the scalp or interfere with the effectiveness of the shampoo. Consult your healthcare provider for specific recommendations.

What should I do if I miss a dose?

If you miss a dose, use the shampoo as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to catch up.

How should I store Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo?

Store the shampoo at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

About this compounded preparation

This formulation is compounded by Bayview Pharmacy on a prescriber's order for an individual patient. It is not an FDA-approved drug product, and the FDA has not evaluated it for safety, effectiveness, or manufacturing quality.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice. Discuss your situation with a licensed healthcare provider.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.
For prescribers

How to e-prescribe this formula

Controlled substance: e-prescribe only (EPCS). Faxed, phoned, and handwritten prescriptions cannot be filled. Rhode Island law (R.I. Gen. Laws § 21-28-3.18) requires Schedule II to V prescriptions to be transmitted electronically.
1

Find Bayview in your EHR's pharmacy directory

Search by NCPDP 4106882, or by name and ZIP: Bayview Pharmacy, Warwick, RI 02886. Select it as the destination pharmacy and save it as a favorite. Click any value to copy it.

NCPDP4106882NPI1750455143Address3844 Post Rd, Warwick, RI 02886Phone(401) 284-4505Fax(401) 284-4506
2

Enter the formula as a compound

Compounded preparations have no NDC, so this formula will not appear in your EHR's drug search. Use your system's compound, non-formulary, or free-text prescription entry and name the preparation exactly as written in step 3. If your EHR forces you to pick a listed drug, pick the closest entry for the active ingredient and put the full formula in the prescription body (the Sig or directions field), not in Notes to Pharmacy.

Compounded preparations have no NDC and will not appear in your drug search. For EPCS to validate, select a drug entry your EHR recognizes as controlled, usually the bulk powder entry for the active ingredient (for example Ketamine (bulk) powder, not a branded product), then put the full formula from step 3 in the prescription body. A free-text entry that does not validate as controlled will be rejected by your EPCS module.

3

Copy the prescription details

RxFormula name
Dose formDose form
Quantity________
SigAs directed by prescriber
Refills____
PharmacyBayview Pharmacy, Warwick RI, NCPDP 4106882
Copy prescription details

Quantity and directions are starting points for this dose form, not treatment recommendations. Dosing remains the prescriber's responsibility.

4

Send it

Transmit from your EHR. For this non-controlled preparation we also accept fax to (401) 284-4506 and phoned orders at (401) 284-4505. Order forms are on the formulation pages and in the prescriber portal.

Transmit with two-factor authentication through your EPCS-enabled EHR. No order form is offered for this preparation; e-prescribing guides for our controlled preparations are on the formulation pages.

Do not use Notes to Pharmacy for the formula. Some EHRs keep that field internal and never transmit it. A prescription that arrives without the formula is delayed while we call your office.

Licensed to dispense in RI, MA, CT, NJ, NH, FL, ME, and PA; New York is served on a limited basis while nonresident registration is pending. Compounded preparations are not FDA-approved. A valid prescription is required. Full guide, including steps by EHR: How to e-prescribe to Bayview. Questions about this formula: call (401) 284-4505.

Clobetasol Propionate 0.5 mg/mL/Pyrithione Zinc 2 mg/mL Shampoo
Shampoo
150 mL
controlled

Apply topically to affected area(s)

Twice weekly