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Active pharmaceutical ingredient

Clarithromycin Hydrochloride

Clarithromycin Hydrochloride is a macrolide antibiotic renowned for its efficacy in treating a variety of bacterial infections.

Compounded to order
Prescription required
Warwick, Rhode Island

About this ingredient

Clarithromycin Hydrochloride is a macrolide antibiotic that is widely used in compounded formulations for its potent antibacterial properties. It is effective against a broad spectrum of bacterial infections, including those caused by Gram-positive and Gram-negative bacteria. This makes it a versatile choice for treating various infections, particularly those affecting the respiratory tract, skin, and soft tissues.

As a semi-synthetic derivative of erythromycin, Clarithromycin Hydrochloride offers improved acid stability and better oral absorption. This enhances its bioavailability and allows for more consistent therapeutic effects. Its mechanism of action involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and proliferation of bacteria.

Clarithromycin Hydrochloride is often preferred in clinical settings due to its favorable pharmacokinetic profile, which includes a longer half-life and the ability to penetrate tissues effectively. This results in sustained antibacterial activity and allows for less frequent dosing, improving patient compliance. Additionally, it has been shown to have anti-inflammatory properties, which can be beneficial in treating infections with an inflammatory component.

In the context of compounding, Clarithromycin Hydrochloride can be formulated into various dosage forms to meet specific patient needs, such as oral suspensions, capsules, or topical preparations. This flexibility is particularly advantageous for patients who may have difficulty swallowing tablets or require tailored dosing regimens. It is important for prescribers to consider potential drug interactions and contraindications, as Clarithromycin Hydrochloride can interact with other medications metabolized by the cytochrome P450 system.

Available formulations

Compounded formulations containing this ingredient

Each of these is compounded to order at our Warwick, Rhode Island pharmacy and requires a prescription.

We do not have a patient page for this ingredient yet. That does not mean we cannot make it. Bayview compounds this ingredient to a prescriber's order, and our full compounding formulary lists every preparation we make. Viewing the formulary requires a prescriber account.

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Compounding formulary

Formulas we compound with this ingredient

A sample of preparations from our formulary. Strengths and dose forms are customised to the prescription.

Common questions

Frequently asked questions

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Related

Related active ingredients

Other salt forms of this molecule, and ingredients commonly compounded alongside it.

Important information

This page describes an active pharmaceutical ingredient, not a finished drug product. Bayview Pharmacy compounds preparations containing it only on a prescriber's order for an individual patient.

Compounded preparations are not FDA-approved, and the FDA has not evaluated them for safety, effectiveness, or manufacturing quality. Nothing on this page is a claim that any preparation is effective for any condition.

A valid prescription is required. Availability depends on Bayview's licensure in your state. This page is general information, not medical advice — discuss your situation with a licensed healthcare provider.

Talk to a compounding pharmacist

Our pharmacists work with prescribers to build preparations around a patient's dose, form and tolerances. Ask us what is possible with this ingredient.