Sublingual Semaglutide and Tirzepatide are now available! Learn More

Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/Progesterone 50-100 mg/Testosterone 0.125-2 mg Troche

This troche is a compounded formulation of Estriol, Estradiol, and Estrone in an 80%-10%-10% ratio, with dosages ranging from 0.625-2.5 mg. It also contains Progesterone (50-100 mg) and Testosterone (0.125-2 mg). It is primarily used for the treatment of menopausal symptoms, endometriosis, uterine fibroids, polycystic ovary syndrome, and hypogonadism.

Want a different strength?
Click the Text Us button below.
To prescribe, you must be a verified prescriber.
To prescribe, you must be in a state where we hold an active out-of-state pharmacy license.
Starting at
Must be E-Prescribed
Get Started
Generate LeafletShow Leaflet
This medication requires a prescription from your doctor
Are you a prescriber? Sign Up
Trusted by 55,278 patients to date.
A group of faces of our past satisfied patients.
A svg symbol of a mortar and pestle with ingredients going in.
Custom made in our compounding labs.
Sliders that show the customization of ingredients.
Personalized treatment for better results.
User with a gear showing the personalization of the formulation.
All strengths and ingredients are tailored to your needs.
This medication is not available at retail pharmacies. It is compounded, and may be more effective at treating you or your patient.
Troches
6427079ea643249f73518ace
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Dosing Calculator

Get general dosing information for a patient by using this calculator.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
Loading icon rotating.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.

Formula Information

A small arrow pointing down

This troche formulation is a compounded blend of estrogens, namely estriol, estradiol, and estrone, in an 80%-10%-10% ratio. It also contains progesterone and testosterone. The dosage ranges for these hormones are as follows: estrogens are present in a 0.625-2.5 mg range, progesterone in a 50-100 mg range, and testosterone in a 0.125-2 mg range. This formulation is primarily used to manage a variety of conditions, including menopausal symptoms, postmenopausal osteoporosis, and hypoestrogenism.

The combination of estrogens in this formulation works synergistically to alleviate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. The inclusion of progesterone is crucial as it helps to mitigate the risk of endometrial hyperplasia and cancer. Testosterone, on the other hand, is known to enhance libido and energy levels. Collectively, these hormones work together to reduce the risk of postmenopausal osteoporosis, a common condition in women after menopause.

This troche formulation is a square-shaped solid dosage form designed to dissolve slowly in the mouth. The medication is delivered through oral mucosa absorption, allowing for targeted local or systemic effects. This method of delivery ensures a steady release of hormones, providing consistent relief from symptoms.

While this formulation is an effective treatment for a variety of disease states and is generally well-tolerated, patients should be aware that it may cause side effects such as nausea, headaches, and breast tenderness. It is important to use this medication as directed by a healthcare professional and to report any adverse effects promptly. If you have any questions or concerns about this formulation, please do not hesitate to reach out for further information.

Drug Interactions

A small arrow pointing down

This troche formulation of Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/Progesterone 50-100 mg/Testosterone 0.125-2 mg is a compounded medication designed to address a range of health conditions, including menopausal symptoms, hypogonadism, and postmenopausal osteoporosis. The formulation contains Estriol, Estradiol, and Estrone, all of which are forms of estrogen. These hormones can help alleviate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. The inclusion of Progesterone in the formulation helps to counterbalance the effects of estrogen and can potentially reduce the risk of endometrial cancer. Testosterone is included to address hypogonadism, a condition characterized by insufficient testosterone production. It can also help reduce the risk of osteoporosis in postmenopausal women.

It's crucial for patients to be aware that this formulation may interact with other medications. These include anticoagulants, anti-seizure medications, and certain antibiotics. Therefore, it's important for patients to inform their healthcare provider of any other medications they are currently taking before starting this formulation. This formulation may also cause side effects such as nausea, headache, and breast tenderness. If patients experience any of these side effects, they should immediately contact their healthcare provider.

If you have any questions or concerns about this formulation or its potential interactions, please don't hesitate to reach out for further information. It's important to us that you feel fully informed and confident in your healthcare decisions.

How Does it Work

A small arrow pointing down

This troche formulation is a compounded medication that contains estriol, estradiol, and estrone in an 80%-10%-10% ratio, with dosages ranging from 0.625-2.5 mg. It also includes progesterone in doses of 50-100 mg and testosterone in doses of 0.125-2 mg. This combination of hormones is designed to treat a variety of conditions, including menopausal symptoms, postmenopausal osteoporosis, and hypogonadism.

Estriol, estradiol, and estrone are all forms of estrogen, a hormone that plays a crucial role in the regulation of the reproductive system. Estriol, the weakest form of estrogen, is primarily used to alleviate menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. Estradiol, the most potent form of estrogen, is used to treat both menopausal symptoms and postmenopausal osteoporosis. Estrone, the most abundant form of estrogen in postmenopausal women, is also used to manage menopausal symptoms.

Progesterone, another hormone included in this formulation, helps regulate the menstrual cycle and is used to treat menopausal symptoms and postmenopausal osteoporosis. Testosterone, a hormone that regulates the reproductive system, is used to treat hypogonadism, a condition characterized by the body's insufficient production of testosterone.

This troche formulation is designed to be taken orally, typically once or twice a day, and dissolves slowly in the mouth for absorption through the oral mucosa. This method of administration allows for targeted local or systemic effects. It is crucial to follow your doctor's instructions when taking this medication. If you have any questions or concerns about this medication, please consult your healthcare provider.

Other Uses

A small arrow pointing down

This compounded formulation of Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/Progesterone 50-100 mg/Testosterone 0.125-2 mg Troche is a versatile treatment option for a range of conditions. It can be effectively used to manage premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome that can cause significant distress. It is also beneficial in treating postpartum depression, a mood disorder that can occur after childbirth, and postmenopausal depression, which can arise during the transition to menopause.

Furthermore, this formulation can address symptoms of androgen deficiency, such as low libido, fatigue, and depression. It is also useful in managing symptoms of adrenal insufficiency, including fatigue, low blood pressure, and low blood sugar. This formulation can also be used to treat symptoms of hypothyroidism, such as fatigue, weight gain, and depression.

Additionally, this formulation can be beneficial for those suffering from polycystic ovary syndrome (PCOS), a hormonal disorder common among women of reproductive age. It can help manage symptoms such as hirsutism (excessive hair growth), acne, and irregular menstrual cycles. If you have any questions about how this formulation can be used to treat any of these conditions, please reach out for further information.

Frequently Asked Questions

A small arrow pointing down

What is the compounded formulation of Estriol/Estradiol/Estrone [80%-10%-10%] 0.625-2.5 mg/Progesterone 50-100 mg/Testosterone 0.125-2 mg Troche?

This is a compounded medication that contains a combination of hormones including Estriol, Estradiol, Estrone, Progesterone, and Testosterone. It is designed to be taken orally and dissolves slowly in the mouth for absorption through the oral mucosa.

What is the purpose of this compounded formulation?

This formulation is typically used for hormone replacement therapy. It can help to balance hormone levels in the body and alleviate symptoms associated with hormonal imbalances, such as those experienced during menopause.

How should I take this medication?

This medication is a troche, which means it should be placed in the mouth and allowed to dissolve slowly. It is not meant to be swallowed whole or chewed.

What does the dosage form mean?

The dosage form refers to the physical form of a dose of medication. In this case, the medication is a square-shaped solid that dissolves slowly in the mouth.

What is the benefit of oral mucosa absorption?

Oral mucosa absorption allows the medication to enter the bloodstream directly, bypassing the digestive system. This can result in a faster onset of action and potentially fewer gastrointestinal side effects.

What are the potential side effects of this medication?

As with any medication, potential side effects can occur. These may include mood changes, weight changes, headaches, and changes in libido. Always consult with your healthcare provider for a complete list of potential side effects.

Can I take this medication if I am pregnant or breastfeeding?

It is important to consult with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before starting any new medication, including this compounded formulation.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take two doses at the same time.

Can I drink alcohol while taking this medication?

It is generally recommended to avoid alcohol while taking this medication as it may interfere with its effectiveness and can potentially increase the risk of side effects.

How should I store this medication?

This medication should be stored at room temperature, away from light and moisture. Keep out of reach of children and pets.

Related Formulas

Related Products
Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.
NEW PRESCRIPTION ORDER FORM
1
Circle for steps.
Patient Information
2
Circle for steps.
Prescriber and Prescription Information
3
Circle for steps.
Fax order form to Bayview Pharmacy at 401-284-4506.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.